Di--keton-hydrazon | 828-77-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: Di--keton-hydrazon
• 英文别名: Dithiophen-2-ylmethylidenehydrazine；dithiophen-2-ylmethylidenehydrazine
• CAS: 828-77-3
• 化学式: C₉H₈N₂S₂
• 分子量: 208.308
• InChiKey: AYZXIXZRNMDUOD-UHFFFAOYSA-N

物化性质

• 熔点：
  62 °C(Solv: methanol (67-56-1); ligroine (8032-32-4))
• 沸点：
  142-155 °C(Press: 0.15 Torr)
• 密度：
  1.38±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  94.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Di--keton-hydrazon 在 三乙胺 作用下， 以 二甲基亚砜 为溶剂， 生成 di(thiophen-2-yl)diazomethane
  参考文献：
  名称：

  New Applications of Hetaryl Thioketones for the Synthesis of Hetaryl-Substituted Ethenes via ‘Two-Fold Extrusion Reaction’

  摘要：

  A series of aryl/hetaryl thioketones was applied for the reactions with aryl/hetaryldiazomethanes yielding, after elimination of N-2, the corresponding thiiranes. The relatively unstable dihetaryldiazomethanes were generated in situ from the corresponding hydrazones by oxidation with DMSO. The obtained thiiranes were converted into tetraaryl/hetaryl-substituted ethenes in good yields by desulfurization performed with tris(diethylamino)phosphine ((Et2N)(3)P).

  DOI：

  10.3987/com-15-s(t)8
• 作为产物：
  描述：

  双(2-噻吩)酮 在 一水合肼 作用下， 以 乙醇 为溶剂， 生成 Di--keton-hydrazon
  参考文献：
  名称：

  New Applications of Hetaryl Thioketones for the Synthesis of Hetaryl-Substituted Ethenes via ‘Two-Fold Extrusion Reaction’

  摘要：

  A series of aryl/hetaryl thioketones was applied for the reactions with aryl/hetaryldiazomethanes yielding, after elimination of N-2, the corresponding thiiranes. The relatively unstable dihetaryldiazomethanes were generated in situ from the corresponding hydrazones by oxidation with DMSO. The obtained thiiranes were converted into tetraaryl/hetaryl-substituted ethenes in good yields by desulfurization performed with tris(diethylamino)phosphine ((Et2N)(3)P).

  DOI：

  10.3987/com-15-s(t)8

文献信息

• New Applications of Hetaryl Thioketones for the Synthesis of Hetaryl-Substituted Ethenes via ‘Two-Fold Extrusion Reaction’
  作者：Heinz Heimgartner、Grzegorz Mlostoń、Katarzyna Urbaniak、Aneta Pawlak

  DOI：10.3987/com-15-s(t)8

  日期：——

  A series of aryl/hetaryl thioketones was applied for the reactions with aryl/hetaryldiazomethanes yielding, after elimination of N-2, the corresponding thiiranes. The relatively unstable dihetaryldiazomethanes were generated in situ from the corresponding hydrazones by oxidation with DMSO. The obtained thiiranes were converted into tetraaryl/hetaryl-substituted ethenes in good yields by desulfurization performed with tris(diethylamino)phosphine ((Et2N)(3)P).