全氟全氢荧蒽 | 662-28-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 中文名称: 全氟全氢荧蒽
• 英文名称: perfluoroperhydrofluoranthene
• 英文别名: hexacosafluoro-hexadecahydro-fluoranthene；Hexacosafluor-hexadecahydro-fluoranthen；1,1,2,2,3,3,3a,4,4,5,5,6,6,6a,6b,7,7,8,8,9,9,10,10,10a,10b,10c-hexacosafluorofluoranthene
• CAS: 662-28-2
• 化学式: C₁₆F₂₆
• 分子量: 686.134
• InChiKey: YEMLBKSPDFVXEO-UHFFFAOYSA-N

物化性质

• 沸点：
  237 °C
• 密度：
  1.94±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  42
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  26

安全信息

• 海关编码：
  2932999099

反应信息

• 作为反应物：
  描述：

  全氟全氢荧蒽 在 iron(III) oxide 作用下， 以 甲醇 为溶剂， 反应 92.0h， 生成 hexafluoro-1,3,4,6-tetramethoxyfluoranthene
  参考文献：
  名称：

  Burdon, James; Gill, Harpal S.; Parsons, Ian W., Journal of the Chemical Society. Perkin transactions I, 1980, p. 1726 - 1730

  摘要：

  DOI：
• 作为产物：
  描述：

  荧蒽 在 cobalt (III) fluoride 作用下， 以51.9 g的产率得到全氟全氢荧蒽
  参考文献：
  名称：

  Burdon, James; Gill, Harpal S.; Parsons, Ian W., Journal of the Chemical Society. Perkin transactions I, 1980, p. 1726 - 1730

  摘要：

  DOI：

文献信息

• Emulsions of perfluorocarbons in aqueous media
  申请人：ISC CHEMICALS LIMITED

  公开号：EP0196776A1

  公开（公告）日：1986-10-08

  Increased stability is conferred on oil-in-water emulsions of perfluorocarbons by addition of a minor (0.1-5% w/v) amount of a fluorinated compound of higher bailing point than the perfluoracarbon being emulsified. The added fluorinated compound is preferably a perfluorinated saturated polycyclic hydrocarbon. The most preferred additive is perfluoroperhydrofluoranthene.

  在全氟碳化合物的水包油乳液中加入少量（0.1-5% w/v）比被乳化的全氟碳化合物燃点更高的含氟化合物，可提高稳定性。添加的含氟化合物最好是全氟饱和多环烃。最理想的添加剂是全氟全氢荧蒽。
• Patient oxygenation using stabilized fluorocarbon emulsions
  申请人：——

  公开号：US20020065326A1

  公开（公告）日：2002-05-30

  Storage stable fluorocarbon emulsions having a continuous aqueous phase and a discontinuous fluorocarbon phase, in which the fluorocarbon phase comprises a major amount of a first fluorocarbon or fluorocarbon mixture, and a minor amount of a second fluorocarbon or fluorocarbon mixture, in which the second fluorocarbon has a molecular weight greater than that of the first fluorocarbon and the second fluorocarbon includes a lipophilic moiety in its structure, whereby the second fluorocarbon serves to promote particle size stability in the emulsion while simultaneously providing favorably short organ retention times when administered to animals in vivo.

  具有连续水相和不连续碳氟化合物相的贮存稳定的碳氟化合物乳液，其中碳氟化合物相包括主要量的第一碳氟化合物或碳氟化合物混合物，以及少量的第二碳氟化合物或碳氟化合物混合物、其中第二碳氟化合物的分子量大于第一碳氟化合物的分子量，且第二碳氟化合物在其结构中包括亲脂分子，由此，第二碳氟化合物可促进乳液中粒度的稳定性，同时在动物体内给药时，可提供较短的器官滞留时间。 体内。
• System for storing and dispensing a gas-solubilized product
  申请人：——

  公开号：US20040166064A1

  公开（公告）日：2004-08-26

  A packaged gas-solubilized product is described. The gas-solubilized product contains a first gas with a first pressure. The product is placed into a flexible inner container made of a gas-impermeable material. The inner container is hermetically disposed inside an outer container. A space formed between the inner and the outer containers is charged with a second gas with an initial charging pressure. The initial charging pressure is higher than the pressure of the first gas contained in the product. Additionally, a product dispenser in a fluid connection with the product contained in the internal container is included. The present invention also provides a method of packaging a gas-solubilized product to prevent a change in the concentration of the gas dissolved in the product during its storage and dispensing.

  描述了一种包装好的气体溶解产品。气溶胶产品含有具有第一压力的第一种气体。产品被放入一个由气体不透性材料制成的柔性内容器中。内容器密封地置于外容器内。在内容器和外容器之间形成的空间充入具有初始充入压力的第二种气体。初始充注压力高于产品中所含第一种气体的压力。此外，还包括一个与内部容器中的产品流体连接的产品分配器。本发明还提供了一种包装气体溶解产品的方法，以防止产品在储存和分配过程中溶解在产品中的气体浓度发生变化。
• Method of Making Perfluorocarbon Emulsions With Non-Fluorinated Surfactants
  申请人：Creech L. Jeffrey

  公开号：US20060193799A1

  公开（公告）日：2006-08-31

  The present invention provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion. The invention also provides another method of making an FC emulsion, which does not require a solid emulsifying agent. The method comprises mixing an FC immiscible hydrophilic liquid and an emulsifying agent to form a first mixture; mixing a stabilizing agent with the first mixture to form a second mixture; and mixing FC with the second mixture to form a third mixture to disperse droplets of FC in the FC immiscible hydrophilic liquid and to form the FC emulsion, wherein the stabilizing agent reduces ability of the droplets to move within a continuous phase of the FC emulsion.

  本发明提供了一种制造 FC 乳液的方法。该方法包括在高于乳化剂相变温度和低于 FC 不溶亲水液体沸腾温度的温度下，通过搅拌将 FC 不溶亲水液体和固体乳化剂混合，并在步骤（a）的混合物中加入 FC，在升高的温度下搅拌，使 FC 液滴分散在 FC 不溶亲水液体中，形成 FC 乳液。本发明还提供了另一种不需要固体乳化剂的 FC 乳液制造方法。该方法包括混合 FC 不溶性亲水液体和乳化剂以形成第一混合物；将稳定剂与第一混合物混合以形成第二混合物；以及将 FC 与第二混合物混合以形成第三混合物，从而将 FC 液滴分散在 FC 不溶性亲水液体中并形成 FC 乳液，其中稳定剂可降低液滴在 FC 乳液连续相内的移动能力。
• Method of Preparing Gas Delivering Perfluorocarbon Emulsions With Non-Fluorinated Surfactants
  申请人：Creech L. Jeffrey

  公开号：US20060193878A1

  公开（公告）日：2006-08-31

  The present invention provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion. The invention also provides another method of making an FC emulsion, which does not require a solid emulsifying agent. The method comprises mixing an FC immiscible hydrophilic liquid and an emulsifying agent to form a first mixture; mixing a stabilizing agent with the first mixture to form a second mixture; and mixing FC with the second mixture to form a third mixture to disperse droplets of FC in the FC immiscible hydrophilic liquid and to form the FC emulsion, wherein the stabilizing agent reduces ability of the droplets to move within a continuous phase of the FC emulsion.

  本发明提供了一种制造 FC 乳液的方法。该方法包括在高于乳化剂相变温度和低于 FC 不溶亲水液体沸腾温度的温度下，通过搅拌将 FC 不溶亲水液体和固体乳化剂混合，并在步骤（a）的混合物中加入 FC，在升高的温度下搅拌，使 FC 液滴分散在 FC 不溶亲水液体中，形成 FC 乳液。本发明还提供了另一种不需要固体乳化剂的 FC 乳液制造方法。该方法包括混合 FC 不溶性亲水液体和乳化剂以形成第一混合物；将稳定剂与第一混合物混合以形成第二混合物；以及将 FC 与第二混合物混合以形成第三混合物，从而将 FC 液滴分散在 FC 不溶性亲水液体中并形成 FC 乳液，其中稳定剂可降低液滴在 FC 乳液连续相内的移动能力。