ethyl-benzyl-hexyl-amine | 855267-57-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl-benzyl-hexyl-amine
• 英文别名: Aethyl-benzyl-hexyl-amin；N-Ethyl-N-hexylbenzenemethanamine；N-benzyl-N-ethylhexan-1-amine
• CAS: 855267-57-1
• 化学式: C₁₅H₂₅N
• 分子量: 219.37
• InChiKey: BJNRFIHKMNSZCR-UHFFFAOYSA-N

物化性质

• 沸点：
  145 °C(Press: 13 Torr)
• 密度：
  0.895±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  ethyl-benzyl-hexyl-amine 在 platinum(IV) oxide 、 溶剂黄146 作用下， 生成 N-乙基己胺
  参考文献：
  名称：

  72.抗血浆作用和化学成分。第五部分衍生自6-甲氧基喹啉的甲醇胺

  摘要：

  DOI：

  10.1039/jr9420000401
• 作为产物：
  描述：

  溴己烷 在 氢氧化钾 作用下， 生成 ethyl-benzyl-hexyl-amine
  参考文献：
  名称：

  72.抗血浆作用和化学成分。第五部分衍生自6-甲氧基喹啉的甲醇胺

  摘要：

  DOI：

  10.1039/jr9420000401

文献信息

• 3-SUBSTITUTED-6-ARYL PYRIDINES
  申请人：Hutchinson Alan J.

  公开号：US20110281837A1

  公开（公告）日：2011-11-17

  3-substituted-6-aryl pyridines of Formula I are provided: wherein R 1 , R 2 , R 3 , R 8 , R 9 , A and Ar are defined herein. Such compounds are ligands of C5a receptors. Preferred compounds of Formula I bind to C5a receptors with high affinity and exhibit neutral antagonist or inverse agonist activity at C5a receptors. The present invention also relates to pharmaceutical compositions comprising such compounds, and to the use of such compounds in treating a variety of inflammatory, cardiovascular, and immune system disorders. In addition, the present invention provides labeled 3-substituted-6-aryl pyridines, which are useful as probes for the localization of C5a receptors.

  本发明提供了式I的3-取代-6-芳基吡啶化合物：其中R1、R2、R3、R8、R9、A和Ar的定义在此处。这些化合物是C5a受体的配体。式I的优选化合物具有高亲和力结合到C5a受体，并在C5a受体上表现出中性拮抗剂或反向激动剂活性。本发明还涉及包含这些化合物的制药组合物，以及将这些化合物用于治疗各种炎症、心血管和免疫系统疾病的用途。此外，本发明提供了标记的3-取代-6-芳基吡啶，可用作C5a受体定位的探针。
• 3-Substituted-6-Aryl Pyridines
  申请人：Hutchison Alan J.

  公开号：US20090176980A1

  公开（公告）日：2009-07-09

  3-substituted-6-aryl pyridines of Formula I are provided: wherein R 1 , R 2 , R 3 , R 8 , R 9 , A and Ar are defined herein. Such compounds are ligands of C5a receptors. Preferred compounds of Formula I bind to C5a receptors with high affinity and exhibit neutral antagonist or inverse agonist activity at C5a receptors. The present invention also relates to pharmaceutical compositions comprising such compounds, and to the use of such compounds in treating a variety of inflammatory, cardiovascular, and immune system disorders. In addition, the present invention provides labeled 3-substituted-6-aryl pyridines, which are useful as probes for the localization of C5a receptors.

  本发明提供了式I中的3-取代-6-芳基吡啶化合物： 其中R1、R2、R3、R8、R9、A和Ar在此定义。这些化合物是C5a受体的配体。式I的优选化合物具有高亲和力结合C5a受体，并在C5a受体上表现出中性拮抗剂或反向激动剂活性。本发明还涉及包含这些化合物的药物组合物，以及在治疗各种炎症，心血管和免疫系统疾病中使用这些化合物的用途。此外，本发明提供了标记的3-取代-6-芳基吡啶，可用作C5a受体的定位探针。
• METALLIC PIGMENT COMPOSITION
  申请人：Asahi Kasei Chemicals Corporation

  公开号：EP2554608A1

  公开（公告）日：2013-02-06

  Disclosed is a metallic pigment composition that can be used in coating compositions or ink compositions, specifically, in water-based coatings and water-based inks, and exhibits superior coating material storage stability. When formed into a coating material, the metallic pigment composition has superior performance for photoluminescence, concealment, flip-flop color and other properties, and does not change the color of dyes or organic pigments. The metallic pigment composition contains: at least one organic molybdenum compound; a hydrolysate of a compound containing silicon and/or a condensate thereof; and metal particles.

  本发明公开了一种金属颜料组合物，它可用于涂料组合物或油墨组合物中，特别是用于水性涂料和水性油墨中，并具有优异的涂层材料储存稳定性。当形成涂层材料时，金属颜料组合物在光致发光、隐蔽性、翻转颜色和其他性能方面具有优异的表现，并且不会改变染料或有机颜料的颜色。金属颜料组合物包含：至少一种有机钼化合物；含硅化合物的水解物和/或其缩合物；以及金属颗粒。
• METALLIC-PIGMENT COMPOSITION
  申请人：Asahi Kasei Chemicals Corporation

  公开号：EP2565238A1

  公开（公告）日：2013-03-06

  Provided is a metallic-pigment composition which is usable in coating compositions or ink compositions, in particular, in water-based coating compositions or aqueous inks, and which gives coating compositions having excellent storage stability. The metallic-pigment composition gives a coating film having excellent performances with respect to brightness, hiding properties, flip-flop feeling, etc., causes no colorant or organic-pigment discoloration, and has excellent adhesion and chemical resistance. The metallic-pigment composition comprises one or more mixed-coordination-type heteropolyanion compounds, a hydrolyzate of a silicon compound and/or a condensate thereof, and metal particles.

  本发明提供了一种金属颜料组合物，它可用于涂料组合物或油墨组合物，特别是用于水基涂料组合物或水性油墨，并使涂料组合物具有优异的储存稳定性。该金属颜料组合物所制成的涂膜在亮度、遮盖力、翻转感等方面性能优异，不会导致着色剂或有机颜料变色，并具有出色的附着力和耐化学性。金属颜料组合物由一种或多种混合配位型杂多阳离子化合物、硅化合物的水解物和/或其缩合物以及金属颗粒组成。
• US7342115B2
  申请人：——

  公开号：US7342115B2

  公开（公告）日：2008-03-11