2,2-bis(toluene-4-sulfonyloxymethyl)propane-1,3-diol | 104274-81-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2-bis(toluene-4-sulfonyloxymethyl)propane-1,3-diol
• 英文别名: [2,2-Bis(hydroxymethyl)-3-(4-methylphenyl)sulfonyloxypropyl] 4-methylbenzenesulfonate
• CAS: 104274-81-9
• 化学式: C₁₉H₂₄O₈S₂
• 分子量: 444.527
• InChiKey: FLFVRODGGKNSCJ-UHFFFAOYSA-N

物化性质

• 沸点：
  664.0±55.0 °C(Predicted)
• 密度：
  1.373±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  144
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2,2-bis(toluene-4-sulfonyloxymethyl)propane-1,3-diol 在 吡啶 、 4-二甲氨基吡啶 作用下， 以 乙二醇二甲醚 、 二氯甲烷 为溶剂， 反应 168.0h， 生成 spiro bis(1H,4H,7H-hexahydro-3a,6a,9a-triazaphenalene)
  参考文献：
  名称：

  Synthesis of 2,6,10,14,18,22-hexaazaspiro[11.11]tricosane, the first example of a spiro aza crown derived from 2,2-bis(aminomethyl)propane-1,3-diamine

  摘要：

  2,10,14, 18,22-Hexaazaspiro[11.11]tricosane 1 has been prepared in seven steps from pentaerythritol. The key steps include two successive cyclizations by displacement of two tosyloxy groups from the appropriate pentaerythritol derivatives (4: 6) with 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD), each reaction being followed by sodium borohydride reduction. Hydrolysis of the spiro bis(hexahydro-1 H,4H,7H-3a,6a,9a-triazaphenalene) formed 1. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00238-6
• 作为产物：
  描述：

  2-苯基-1,3二恶烷-5,5-二甲氨基)二(亚甲基)二(4-甲基苯磺酸) 在 palladium on activated charcoal 氢气 作用下， 以 乙醇 为溶剂， 20.0 ℃ 、506.62 kPa 条件下， 反应 15.0h， 以99.1%的产率得到2,2-bis(toluene-4-sulfonyloxymethyl)propane-1,3-diol
  参考文献：
  名称：

  Synthesis of 2,6,10,14,18,22-hexaazaspiro[11.11]tricosane, the first example of a spiro aza crown derived from 2,2-bis(aminomethyl)propane-1,3-diamine

  摘要：

  2,10,14, 18,22-Hexaazaspiro[11.11]tricosane 1 has been prepared in seven steps from pentaerythritol. The key steps include two successive cyclizations by displacement of two tosyloxy groups from the appropriate pentaerythritol derivatives (4: 6) with 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD), each reaction being followed by sodium borohydride reduction. Hydrolysis of the spiro bis(hexahydro-1 H,4H,7H-3a,6a,9a-triazaphenalene) formed 1. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00238-6

文献信息

• Process For The Preparation Of Polycarbonate By The Melt Transesterification Process
  申请人：Fischer Peter

  公开号：US20080319156A1

  公开（公告）日：2008-12-25

  The invention provides a process for the preparation of polycarbonate by the melt transesterification process, polycarbonate having a low electrostatic charge obtainable by this process, and mouldings or extrudates, in particular optical data storage media or light-diffusing plates, made from this polycarbonate.
• US7814626B2
  申请人：——

  公开号：US7814626B2

  公开（公告）日：2010-10-19
• Synthesis of 2,6,10,14,18,22-hexaazaspiro[11.11]tricosane, the first example of a spiro aza crown derived from 2,2-bis(aminomethyl)propane-1,3-diamine
  作者：Qi Wang、Satu Mikkola、Harri Lönnberg

  DOI：10.1016/s0040-4039(01)00238-6

  日期：2001.4

  2,10,14, 18,22-Hexaazaspiro[11.11]tricosane 1 has been prepared in seven steps from pentaerythritol. The key steps include two successive cyclizations by displacement of two tosyloxy groups from the appropriate pentaerythritol derivatives (4: 6) with 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD), each reaction being followed by sodium borohydride reduction. Hydrolysis of the spiro bis(hexahydro-1 H,4H,7H-3a,6a,9a-triazaphenalene) formed 1. (C) 2001 Elsevier Science Ltd. All rights reserved.