pentaerythritol dipropionate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: pentaerythritol dipropionate
• 英文别名: [2,2-bis(hydroxymethyl)-3-propanoyloxypropyl] propanoate
• 化学式: C₁₁H₂₀O₆
• 分子量: 248.276
• InChiKey: CEKVYFNTUVJDAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3,9-dibenzyloxy-3,9-diethyl-2,4,8,10-tetraoxaspiro<5,5>undecane 在 水 、 顺丁烯二酸 作用下， 以 1,4-二氧六环 为溶剂， 生成 pentaerythritol dipropionate 、 Propionic acid 2-benzyloxy-2-ethyl-5-hydroxymethyl-[1,3]dioxan-5-ylmethyl ester 、 苯甲醇
  参考文献：
  名称：

  在均质溶液中水解某些聚原酸酯。

  摘要：

  聚原酸酯和单体模型化合物3,9-二苄氧基-3,9-二乙基-2,4,8,10-四氧杂螺[5,5]十一烷的水解反应-d8-二恶烷和随后的1 H-NMR和HPLC。实验结果表明，聚合物的降解在很大程度上是通过随机断裂进行的。酸催化水解。随着酸的含水pKa的降低，催化速率常数可预期地增加。就催化剂浓度和存在的原酸酯键的数目而言，该反应是一级反应，并且在所研究的浓度范围内，该反应与水无关。原酸酯键处的应变可能是影响水解速率的因素。

  DOI：

  10.1002/jps.2600731119

文献信息

• Hydrolysis of Some Poly(ortho-ester)s in Homogeneous Solutions
  作者：Tue Huu Nguyen、Chung Shih、Kenneth J. Himmelstein、Takeru Higuchi

  DOI：10.1002/jps.2600731119

  日期：1984.11

  The hydrolysis of poly(ortho-ester)s and a monomeric model compound, 3,9-dibenzyloxy-3,9-diethyl-2,4,8,10-tetraoxaspiro[5,5]un decane, was carried out in dioxane-d8-dioxane and followed by 1H-NMR and HPLC, respectively. Experimental results suggested that the polymer degradation proceeds to a large extent via random scission. The hydrolysis was catalyzed by the acid; the catalytic rate constant increased

  聚原酸酯和单体模型化合物3,9-二苄氧基-3,9-二乙基-2,4,8,10-四氧杂螺[5,5]十一烷的水解反应-d8-二恶烷和随后的1 H-NMR和HPLC。实验结果表明，聚合物的降解在很大程度上是通过随机断裂进行的。酸催化水解。随着酸的含水pKa的降低，催化速率常数可预期地增加。就催化剂浓度和存在的原酸酯键的数目而言，该反应是一级反应，并且在所研究的浓度范围内，该反应与水无关。原酸酯键处的应变可能是影响水解速率的因素。
• Bioerodible thermoset elastomers
  申请人：MERCK & CO. INC.

  公开号：EP0419156A2

  公开（公告）日：1991-03-27

  Bioerodible, thermoset, covalently crosslinked, elastomeric poly(ortho ester)s are disclosed. These materials are comprised of polymer chains that are interlocked in a covalent, three dimensional network which imparts dimensional stability. Use of these thermoset, covalently crosslinked materials as a drug delivery device is also disclosed

  本发明公开了可生物降解的热固性共价交联弹性聚（原生酯）。这些材料由聚合物链组成，这些聚合物链在共价三维网络中相互交错，从而增强了尺寸稳定性。还公开了这些热固性共价交联材料作为给药装置的用途
• High strain gels, gel composites and artificial muscel actuators made thereform
  申请人：——

  公开号：US20030122446A1

  公开（公告）日：2003-07-03

  Novel gels and articles are formed from one or more copolymers having at least one poly(ethylene) components and high levels of one or more plasticizers, said gels having an amount of crystallinity, glassy components, and selected plasticizers sufficient to achieve improvements in one or more physical properties including improved crack propagation resistance, improved tear resistance, improved resistance to fatigue, resistance to catastrophic failure, and exhibiting high strain under elongations not obtainable in amorphous gels which high strain making the gel suitable for use as film layers for artificial muscles.

  新型凝胶和物品由一种或多种共聚物形成，这些共聚物具有至少一种聚（乙烯）成分和高含量的一种或多种增塑剂，所述凝胶具有一定量的结晶度、玻璃状成分和选定的增塑剂，足以改善一种或多种物理性能，包括改善抗裂纹扩展能力、改善抗撕裂能力、改善抗疲劳能力、抗灾难性破坏能力，并表现出无定形凝胶无法获得的高伸长应变，这种高应变使凝胶适合用作人造肌肉的薄膜层。
• Retention Indices and Sorption Enthalpies of Pentaerythritol and С2–С8 Acid Esters on Nonpolar Stationary Phases
  作者：V. V. Emel’yanov、E. L. Krasnykh、S. V. Portnova

  DOI：10.1134/s003602442010009x

  日期：2020.10

  The retention and sorption enthalpy characteristics of 38 pentaerythritol esters of C-2-C(8)carboxylic acids of different structures were determined by gas-liquid chromatography on a nonpolar phase in the temperature range 433.2-563.2 K. The molecular structure was shown to affect the temperature dependence of the retention indices of the esters. The average change in the sorption enthalpy of pentaerythritol tetraesters per CH(2)group is lower in magnitude than the similar contribution for normal alkanes. The excess mixing enthalpy at 298.2 K was evaluated for four fully substituted pentaerythritol esters.
• POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME
  申请人：Medtronic, Inc.

  公开号：EP2044142A2

  公开（公告）日：2009-04-08