olivetol carboxylic acid dimethyl ether | 52189-65-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: olivetol carboxylic acid dimethyl ether
• 英文别名: 2,4-dimethoxy-6-pentylbenzoic acid；2,4-dimethoxy-6-pentyl-benzoic acid；2,4-Dimethoxy-6-pentyl-benzoesaeure；2.4-Dimethoxy-6-n-pentyl-benzoesaeure；Dimethylaether-olivetolcarbonsaeure；2,4-Dimethoxy-6-pentylbenzoesaeure
• CAS: 52189-65-8
• 化学式: C₁₄H₂₀O₄
• 分子量: 252.31
• InChiKey: ZGQDKQGOSJZNGR-UHFFFAOYSA-N

物化性质

• 熔点：
  53-54 °C(Solvent: Hexane)
• 沸点：
  370.8±37.0 °C(Predicted)
• 密度：
  1.086±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  olivetol carboxylic acid dimethyl ether 在 溴 、 溶剂黄146 作用下， 生成 2,4-dibromo-1,5-dimethoxy-3-pentylbenzene
  参考文献：
  名称：

  Asahina; Yasue, Chemische Berichte, 1937, vol. 70, p. 206,209

  摘要：

  DOI：
• 作为产物：
  描述：

  3,5-二甲氧基苯甲酸 在 tetrafluoroboric acid 、 lithium 、 sodium nitrite 作用下， 以 水 为溶剂， 反应 2.0h， 生成 olivetol carboxylic acid dimethyl ether
  参考文献：
  名称：

  Durrani, Aziz A.; Tyman, John H. P., Journal of the Chemical Society. Perkin transactions I, 1980, p. 1658 - 1666

  摘要：

  DOI：

文献信息

• [EN] METHODS FOR SYNTHESIS OF CANNABINOID COMPOUNDS<br/>[FR] PROCÉDÉS DE SYNTHÈSE DE COMPOSÉS CANNABINOÏDES
  申请人：BEETLEBUNG PHARMA LTD

  公开号：WO2020031179A1

  公开（公告）日：2020-02-13

  The present invention provides simple synthetic routes for the preparation of cannabinoid compounds such as CBD, CBDV, THC, THCV, CBN, HU-308, CBG, CBC, and derivatives thereof, which are stereoselective and provide the desired cannabinoid compound in high yield.

  本发明提供了制备大麻素化合物（如CBD、CBDV、THC、THCV、CBN、HU-308、CBG、CBC以及它们的衍生物）的简单合成途径，这些途径具有立体选择性并且能够高产率地提供所需的大麻素化合物。
• Un marco biológico para entender el fitomejoramiento de los agricultures
  作者：David A. Cleveland、Soleri Daniela、Steven E. Smith

  DOI：10.1007/bf02864788

  日期：2000.7

  We present a framework for understanding farmer plant breeding (including both choice of varieties and populations and plant selection) in terms of the basic biological model of scientific plant breeding, focusing on three key components of that model: 1) genetic variation, 2) environmental variation and variation of genotype-by-envivonment interaction, and 3) plant selection. For each of these concepts we suggest questions for research on fanners' plant breeding (farmers' knowledge, practice, and crop varieties and growing environments). A sample of recent research shows a range of explicit and implicit answers to these questions which are often contradictory, suggesting that generalizations based on experience with specific varieties, environments or farmers may not be valid. They also suggest that farmers' practice reflects an understanding of their crop varieties and populations that is in many ways fundamentally similar to that of plant breeders; yet, is also different, in part because the details of their experiences are different. Further research based on this framework should be valuable for participatory or collaborative plant breeding that is currently bring proposed to reunite farmer and scientific plans breeding.
• Medicinal plants used by latino healers for women’s health conditions in New York City
  作者：Michael J. Balick、Fredi Kronenberg、Andreana L. Ososki、Marian Reiff、Adriane Fugh-Berman、O’Connor Bonnie、Maria Roble、Patricia Lohr、Daniel Atha

  DOI：10.1007/bf02864786

  日期：2000.7

  This paper examines rite use of medicinal plants by Latino healers in New York City to treat various, women's illnesses. Eight Latino healers collaborated on the study through consultations with female patients who had one of the following conditions as diagnosed by biomedically trained physicians: uterine fibroids, hot flashes,,menorrhagia, or endometrosis. The study identified a total of 67 plant species prescribed by the healers in the form of mixtures or as individual plants. Voucher specimens were collected from local botanicas and identified by specialists at The New. York Botanical Garden. Studies of immigrant traditional healers and the plants they use in an urban setting ran provide interesting ethnobotanical data and information to assist in diagnosing conditions and contributing to treatment of patients from Latino as, well as non-Latino communities.
• Asahina; Fujikawa, Chemische Berichte, 1935, vol. 68, p. 634,636, 638
  作者：Asahina、Fujikawa

  DOI：——

  日期：——
• Elix, John A.; Barclay, Caroline E.; David, Feeya, Australian Journal of Chemistry, 1993, vol. 46, # 3, p. 301 - 313
  作者：Elix, John A.、Barclay, Caroline E.、David, Feeya、Griffin, Frank K.、Hill, Alison M.、et al.

  DOI：——

  日期：——