5,5'-di-tert-butyl-6,6'-dihydroxy-3,3'-(propane-2,2-diyl)dibenzaldehyde | 457658-13-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5,5'-di-tert-butyl-6,6'-dihydroxy-3,3'-(propane-2,2-diyl)dibenzaldehyde
• 英文别名: 3-Tert-butyl-5-[2-(3-tert-butyl-5-formyl-4-hydroxyphenyl)propan-2-yl]-2-hydroxybenzaldehyde
• CAS: 457658-13-8
• 化学式: C₂₅H₃₂O₄
• 分子量: 396.527
• InChiKey: UCQDUCGKYXDJMM-UHFFFAOYSA-N

物化性质

• 沸点：
  444.8±40.0 °C(Predicted)
• 密度：
  1.112±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine 、 5,5'-di-tert-butyl-6,6'-dihydroxy-3,3'-(propane-2,2-diyl)dibenzaldehyde 以 乙醇 、 二氯甲烷 为溶剂， 以89%的产率得到5,5-(2',2'-dimethylpropane)-di-[(R,R)-{N-(3-tert-butylsalicylidine)-N'-(3',5'-di-tert-butylsalicylidine)}-1,2-cyclohexanediamine]
  参考文献：
  名称：

  Enantioselective epoxidation of nonfunctionalized alkenes catalyzed by recyclable new homochiral dimeric Mn(III) salen complexes

  摘要：

  Two recyclable dimeric Multi salen complexes with geminal methyl groups on the linking carbon atom at the 5,5' position of the salen units were synthesized. They gave a high epoxide yield (> 99%) and enantiomeric excess up to > 99% in 2 to 11 h at 2 mol% catalyst loading in the enantioselective epoxidation of nonfunctionalized alkenes using NaOCl as the oxidant in the presence of Py N-O as the axial base. The epoxidation reaction was successful even at a catalyst loading of 0.4 mol%, but the reaction took longer. The catalyst was recovered easily and recycled five times in a simple separation process. To understand the mechanism of the catalytic reaction, the kinetic investigation was carried out with different concentrations of the catalyst, the oxidant, and the substrate and with styrene as the representative substrate. The epoxidation of styrene was first order with respect to the catalyst and the oxidant but did not depend on the initial concentration of the substrate. An appropriate mechanism of the epoxidation reaction is proposed. (C) 2004 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.jcat.2004.02.037
• 作为产物：
  描述：

  2-叔丁基苯酚 、 alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 、 硫化氢 、 溶剂黄146 作用下， 以 Petroleum ether 为溶剂， 反应 73.0h， 生成 5,5'-di-tert-butyl-6,6'-dihydroxy-3,3'-(propane-2,2-diyl)dibenzaldehyde
  参考文献：
  名称：

  新型可回收的手性聚salen-Mn（III）配合物催化未官能化烯烃的高度对映选择性环氧化

  摘要：

  合成了一种新的可溶性可循环利用的聚salen-Mn（III）配合物，发现该化合物对未官能化的烯烃的不对称环氧化具有很高的对映选择性（高达ee的97％）。

  DOI：

  10.1039/b201294b

文献信息

• NOVEL BIS(FORMYLPHENYL)ALKANE AND NOVEL POLYNUCLEAR PHENOL DERIVED FROM THE SAME
  申请人：Yoshitomo Akira

  公开号：US20100016633A1

  公开（公告）日：2010-01-21

  Manufacture a novel bis(formylphenyl)alkane according to General Formula (1), as well as a novel polynuclear phenol derived therefrom, by causing a bis(hydroxymethyl-hydroxyphenyl)alkane to react with hexamethylene tetramine in the presence of an acid and hydrolyzing the reaction product, and then using the obtained bis(hydroxy-formylphenyl)alkane as a direct material and causing this material to react with halogenated alkoxycarbonyl hydrocarbon in the presence of a base.

  根据通用公式（1），制造一种新型双(甲醛苯基)烷，并由此制备一种新型多核酚，方法是使双(羟甲基-羟基苯基)烷在酸的存在下与六亚甲基四胺反应并水解反应产物，然后使用得到的双(羟基-甲醛苯基)烷作为直接原料，使其在碱的存在下与卤代烷氧羰基碳氢化合物反应。
• Enantioselective epoxidation of nonfunctionalized alkenes catalyzed by recyclable new homochiral dimeric Mn(III) salen complexes
  作者：Rukhsana I. Kureshy、Noor-ul H. Khan、Sayed H.R. Abdi、Surendra Singh、Irshad Ahmad、Raksh V. Jasra、Amish P. Vyas

  DOI：10.1016/j.jcat.2004.02.037

  日期：2004.6.10

  Two recyclable dimeric Multi salen complexes with geminal methyl groups on the linking carbon atom at the 5,5' position of the salen units were synthesized. They gave a high epoxide yield (> 99%) and enantiomeric excess up to > 99% in 2 to 11 h at 2 mol% catalyst loading in the enantioselective epoxidation of nonfunctionalized alkenes using NaOCl as the oxidant in the presence of Py N-O as the axial base. The epoxidation reaction was successful even at a catalyst loading of 0.4 mol%, but the reaction took longer. The catalyst was recovered easily and recycled five times in a simple separation process. To understand the mechanism of the catalytic reaction, the kinetic investigation was carried out with different concentrations of the catalyst, the oxidant, and the substrate and with styrene as the representative substrate. The epoxidation of styrene was first order with respect to the catalyst and the oxidant but did not depend on the initial concentration of the substrate. An appropriate mechanism of the epoxidation reaction is proposed. (C) 2004 Elsevier Inc. All rights reserved.
• A NOVEL TRANSITION METAL BASED PRO-CATALYST AND A PROCESS FOR ITS PREPARATION
  申请人：RELIANCE INDUSTRIES LIMITED

  公开号：US20160108146A1

  公开（公告）日：2016-04-21

  The present disclosure relates to a transition metal based pro-catalyst represented by Formula I: wherein, the substituents have the meaning as defined in the specification. The present disclosure also relates to a process for preparing the transition metal based pro-catalyst represented by Formula I and the catalyst composition obtained therefrom. Further, the present disclosure relates to a process for polymerizing olefins by employing the catalyst composition comprising the transition metal based pro-catalyst represented by Formula I.
• US7875743B2
  申请人：——

  公开号：US7875743B2

  公开（公告）日：2011-01-25
• US9611345B2
  申请人：——

  公开号：US9611345B2

  公开（公告）日：2017-04-04