ethyl-norborn-5-en-2-yl sulfide | 100145-49-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: ethyl-norborn-5-en-2-yl sulfide
• 英文别名: Aethyl-norborn-5-en-2-yl-sulfid；2-Aethylmercapto-bicyclo<2.2.1>hept-5-en；5-Ethylsulfanylbicyclo[2.2.1]hept-2-ene
• CAS: 100145-49-1
• 化学式: C₉H₁₄S
• 分子量: 154.276
• InChiKey: GDWGBBXYDRZTMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  环戊二烯 、 乙基乙烯基硫醚 生成 ethyl-norborn-5-en-2-yl sulfide
  参考文献：
  名称：

  Coffee and Alcohol Intake and Risk of Ovarian Cancer: An Italian Case-Control Study

  摘要：

  The relation between coffee and alcohol intake and ovarian cancer risk was analyzed in a case-control study conducted in Italy between 1992 and 1999. Cases were 1,031 women, aged 18-79 years, with incident, histologically confirmed invasive epithelial ovarian cancer, and controls were 2,411 women, aged 17-79 years, admitted to the hospital for acute nonneoplastic non-hormone-related diseases. Coffee intake (mostly espresso and mocha) was not associated with ovarian cancer risk, with an odds ratio (OR) of 0.93 [95 % confidence interval (CI) = 0.69-1.27] in drinkers of greater than or equal to4 cups/day compared with drinkers of <1 cup/day. No meaningful relation was observed with cappuccino (OR = 1.06, 95% CI = 0.85-1,32 for drinkers compared with nondrinkers), decaffeinated coffee (OR = 0.64, 95% CI 0.42-0.96), and tea intake (OR = 0.90, 95% CI = 0.75-1,08). Total alcohol intake was not associated with ovarian cancer risk (OR = 1.09, 95 % CI = 0.76-1.57 in drinkers of greater than or equal to 36 g/day compared with never drinkers), No relationship was found with wine (OR = 1.03, 95% CI = 0.70-1.50 for > 39 g/day compared with never drinkers), beer, amari, grappa, and spirits. No significant heterogeneity was found for coffee or total alcohol intake across strata of age, education, parity, oral contraceptive use, family history of ovarian/breast cancer, body mass index, and calorie intake, This study, based on a large data set, provides no support for a causal association between invasive epithelial ovarian cancer risk and coffee and alcohol intake.

  DOI：

  10.1207/s15327914nc391_4

文献信息

• Vinyl compounds in diene synthesis
  作者：M. F. Shostakovskii、A. V. Bogdanova、T. M. Ushakova、B. V. Lopatin

  DOI：10.1007/bf00909413

  日期：1961.1
• Film Comprising Norbornene Compound Addition Polymer
  申请人：Ishiguro Atsushi

  公开号：US20090275719A1

  公开（公告）日：2009-11-05

  [Problems] To provide a film comprising a norbornene (NB) compound addition polymer that is excellent in chemical resistance, optical properties and the like, has a high Tg, a low water absorption ratio and a low linear expansion coefficient, and is soluble in an ordinary solvent. [Means for Solving Problems] A film comprising a NB compound addition polymer essentially consisting of repeating units derived from NB compound monomers, wherein the addition polymer has a specific Mw and has a sum of the units (A1) and (A2) of 70% by mol or more based on the total units, wherein the molar number of each unit satisfies the following equations: 70/30≦[(A1)+(A2)}/(B)]≦100 and 10/90≦(A1)/(A2)≦98/2, or the addition polymer has a specific Mw and Mn and essentially consists of the units (A1) and (B), wherein the molar number of each unit satisfies the following equation: 70/30≦[(A1)/(B)]≦98/2: (A1) a unit derived from a NB compound monomer (a1) consisting of carbon atoms and hydrogen atoms with all the carbon atoms being involved in constitution of a condensed ring skeleton; (A2) a unit derived from a monomer having a structure wherein a part of hydrogen atoms of the monomer (a1) is substituted with only a hydrocarbon group having 2 or less carbon atoms; and (B) a unit derived from a monomer having a structure wherein a part of hydrogen atoms of the monomer (a1) is substituted with only a functional group having 2 or less carbon atoms, or with only a functional group having 2 or less carbon atoms and a hydrocarbon group having 2 or less carbon atoms.
• US4033982A
  申请人：——

  公开号：US4033982A

  公开（公告）日：1977-07-05
• US8013090B2
  申请人：——

  公开号：US8013090B2

  公开（公告）日：2011-09-06
• Coffee and Alcohol Intake and Risk of Ovarian Cancer: An Italian Case-Control Study
  作者：Alessandra Tavani、Silvano Gallus、Luigino Dal Maso、Silvia Franceschi、Silvia Maurizio Montella、Ettore Conti、Carlo La Vecchia

  DOI：10.1207/s15327914nc391_4

  日期：2001.1

  The relation between coffee and alcohol intake and ovarian cancer risk was analyzed in a case-control study conducted in Italy between 1992 and 1999. Cases were 1,031 women, aged 18-79 years, with incident, histologically confirmed invasive epithelial ovarian cancer, and controls were 2,411 women, aged 17-79 years, admitted to the hospital for acute nonneoplastic non-hormone-related diseases. Coffee intake (mostly espresso and mocha) was not associated with ovarian cancer risk, with an odds ratio (OR) of 0.93 [95 % confidence interval (CI) = 0.69-1.27] in drinkers of greater than or equal to4 cups/day compared with drinkers of <1 cup/day. No meaningful relation was observed with cappuccino (OR = 1.06, 95% CI = 0.85-1,32 for drinkers compared with nondrinkers), decaffeinated coffee (OR = 0.64, 95% CI 0.42-0.96), and tea intake (OR = 0.90, 95% CI = 0.75-1,08). Total alcohol intake was not associated with ovarian cancer risk (OR = 1.09, 95 % CI = 0.76-1.57 in drinkers of greater than or equal to 36 g/day compared with never drinkers), No relationship was found with wine (OR = 1.03, 95% CI = 0.70-1.50 for > 39 g/day compared with never drinkers), beer, amari, grappa, and spirits. No significant heterogeneity was found for coffee or total alcohol intake across strata of age, education, parity, oral contraceptive use, family history of ovarian/breast cancer, body mass index, and calorie intake, This study, based on a large data set, provides no support for a causal association between invasive epithelial ovarian cancer risk and coffee and alcohol intake.