4(n-Dodecylthio)thiophenol | 56056-60-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 英文名称: 4(n-Dodecylthio)thiophenol
• 英文别名: 4-(Dodecylsulfanyl)benzene-1-thiol；4-dodecylsulfanylbenzenethiol
• CAS: 56056-60-1
• 化学式: C₁₈H₃₀S₂
• 分子量: 310.568
• InChiKey: ATWXOWSCVHZPII-UHFFFAOYSA-N

物化性质

• 沸点：
  419.2±28.0 °C(Predicted)
• 密度：
  0.98±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  26.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4(n-Dodecylthio)thiophenol 在 吡啶 、 氢氧化钾 、 氯化亚砜 、 铜 、 红铝 作用下， 生成 2-(4-n-Dodecylthiophenylthio)benzylchlorid
  参考文献：
  名称：

  8-Alkylthio-10-piperazinodibenzo[b,f]thiepins

  摘要：

  DOI：

  10.1135/cccc19743338
• 作为产物：
  描述：

  (n-dodecylthio)benzene 生成 4(n-Dodecylthio)thiophenol
  参考文献：
  名称：

  8-Alkylthio-10-piperazinodibenzo[b,f]thiepins

  摘要：

  DOI：

  10.1135/cccc19743338

文献信息

• PROOXIDATIVE CHAIN-TRANSFER AGENTS FOR USE IN THE TREATMENT OF MALIGNANT TUMOUR OR INFECTIOUS DISEASES
  申请人：Universitätsmedizin der Johannes Gutenberg-Universität Mainz

  公开号：EP3827816A1

  公开（公告）日：2021-06-02

  The present invention relates to prooxidative chain-transfer agents for use in the treatment of a malignant tumour disease, or infectious disease. The prooxidative chain-transfer agents are selected from lipophilic thiols, lipophilic trithiocarbonates, lipophilic, aromatic dithioesters, and lipophilic, aromatic thiols. The compounds amplify the prooxidative activity at the target site and are therefore highly efficient and specific for their targets.

  本发明涉及用于治疗恶性肿瘤疾病或传染性疾病的促氧化链转移剂。促氧化链转移剂选自亲脂性硫醇、亲脂性三硫代碳酸盐、亲脂性芳香族二硫代酯和亲脂性芳香族硫醇。这些化合物能放大目标部位的促氧化活性，因此对其目标具有高效和特异性。
• Prooxidative chain-transfer agents for use in the treatment of malignant tumour or infectious diseases
  申请人：Universitätsmedizin der Johannes Gutenberg-Universität Mainz

  公开号：US20220387369A1

  公开（公告）日：2022-12-08

  Prooxidative chain-transfer agents for use in the treatment of a malignant tumour disease, or infectious disease. The prooxidative chain-transfer agents are selected from lipophilic thiols, lipophilic trithiocarbonates, lipophilic, aromatic dithioesters, and lipophilic, aromatic thiols. The compounds amplify the prooxidative activity at the target site and are therefore highly efficient and specific for their targets.
• [EN] PROOXIDATIVE CHAIN-TRANSFER AGENTS FOR USE IN THE TREATMENT OF MALIGNANT TUMOUR OR INFECTIOUS DISEASES<br/>[FR] AGENTS DE TRANSFERT DE CHAÎNE PRO-OXYDANTS DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT DE TUMEURS MALIGNES OU DE MALADIES INFECTIEUSES
  申请人：UNIV DER JOHANNES GUTENBERG UNIV MAINZ

  公开号：WO2021105435A1

  公开（公告）日：2021-06-03

  The present invention relates to prooxidative chain-transfer agents for use in the treatment of a malignant tumour disease, or infectious disease. The prooxidative chain-transfer agents are selected from lipophilic thiols, lipophilic trithiocarbonates, lipophilic, aromatic dithioesters, and lipophilic, aromatic thiols. The compounds amplify the prooxidative activity at the target site and are therefore highly efficient and specific for their targets.
• 8-Alkylthio-10-piperazinodibenzo[b,f]thiepins
  作者：J. O. Jílek、J. Metyšová、J. Pomykáček、M. Protiva

  DOI：10.1135/cccc19743338

  日期：——