3-溴-2,3-二甲基-丁-1-烯 | 109929-23-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机溴化物
• 中文名称: 3-溴-2,3-二甲基-丁-1-烯
• 英文名称: 3-bromo-2,3-dimethyl-but-1-ene
• 英文别名: 3-Brom-2,3-dimethyl-but-1-en；γ-Brom-β.γ-dimethyl-α-butylen；3-Bromo-2,3-dimethylbut-1-ene
• CAS: 109929-23-9
• 化学式: C₆H₁₁Br
• 分子量: 163.057
• InChiKey: RBRSOGGJRXZNKY-UHFFFAOYSA-N

物化性质

• 沸点：
  84-86 °C(Press: 100 Torr)
• 密度：
  1.2201 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  3-溴-2,3-二甲基-丁-1-烯 在 potassium carbonate 作用下， 生成 2,3-二甲基-3-丁烯-2-醇
  参考文献：
  名称：

  Preference to have used a medically supervised injecting centre among injecting drug users in Kings Cross, Sydney

  摘要：

  Objective: To assess factors affecting preference to have last injected in a medically supervised injecting centre (MSIC) among injecting drug users (IDUs) attending a needle syringe program (NSP) in Kings Cross, Sydney. Methods: All NSP attenders over a two-day period in August 1999 were asked where they last injected, whether they injected alone and if they would have preferred to use an MSIC. This was in addition to the routine data collected, which included age, gender and last drug injected. Results: Among the 178 respondents, 52 (29%) last injected in a public place and 77 (44%) last injected alone. Seventy-one per cent of all respondents would have preferred to use an MSIC. Of those who injected in public, 83% would have preferred to use an MSIC compared to 66% of those who injected in private, which was significant (p = 0.03). Age, gender, last drug injected and having injected alone did not affect preference to use an MSIC. Conclusions: Respondents' high preference to use an MSIC suggests that it may well achieve its public order and public health objectives. Implications: An MSIC may significantly shift current patterns of illicit drug use in Kings Cross, the community impact of which should be monitored and managed.

  DOI：

  10.1111/j.1467-842x.2000.tb00507.x
• 作为产物：
  描述：

  2,3-二甲基-1,3-丁二烯 在 氢溴酸 、 溶剂黄146 作用下， 生成 3-溴-2,3-二甲基-丁-1-烯
  参考文献：
  名称：

  Preference to have used a medically supervised injecting centre among injecting drug users in Kings Cross, Sydney

  摘要：

  Objective: To assess factors affecting preference to have last injected in a medically supervised injecting centre (MSIC) among injecting drug users (IDUs) attending a needle syringe program (NSP) in Kings Cross, Sydney. Methods: All NSP attenders over a two-day period in August 1999 were asked where they last injected, whether they injected alone and if they would have preferred to use an MSIC. This was in addition to the routine data collected, which included age, gender and last drug injected. Results: Among the 178 respondents, 52 (29%) last injected in a public place and 77 (44%) last injected alone. Seventy-one per cent of all respondents would have preferred to use an MSIC. Of those who injected in public, 83% would have preferred to use an MSIC compared to 66% of those who injected in private, which was significant (p = 0.03). Age, gender, last drug injected and having injected alone did not affect preference to use an MSIC. Conclusions: Respondents' high preference to use an MSIC suggests that it may well achieve its public order and public health objectives. Implications: An MSIC may significantly shift current patterns of illicit drug use in Kings Cross, the community impact of which should be monitored and managed.

  DOI：

  10.1111/j.1467-842x.2000.tb00507.x

文献信息

• Process for Production of 5-Alkoxy-4-Hydroxymethylpyrazole Compound
  申请人：Uchida Yukio

  公开号：US20090036688A1

  公开（公告）日：2009-02-05

  The present invention relates to a process for producing a 5-alkoxy-4-hydroxymethylpyrazole compound represented by the general formula (3) which comprises reacting a pyrazole compound represented by the general formula (1) (wherein R 1 is a substituent such as alkyl group, substituted or unsubstituted group or the like, and R 2 is an electron withdrawing group) with a compound represented by the general formula (2) L-R 3 (2) (wherein L is a leaving group and R 3 is a substituent such as substituted or unsubstituted alkyl group or the like) in the presence of a base and formaldehyde.

  本发明涉及一种制备5-烷氧基-4-羟甲基吡唑化合物的方法，该化合物由通式（3）表示，其中，该方法包括在碱和甲醛的存在下，将通式（1）所表示的吡唑化合物（其中，R1是取代基，例如烷基，取代或未取代基或类似基团，而R2是电子提取基团）与通式（2）所表示的化合物L-R3（2）（其中，L是离去基团，而R3是取代或未取代的烷基或类似基团）反应。
• PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND
  申请人：IHARA CHEMICAL INDUSTRY CO., LTD.

  公开号：EP1990336B1

  公开（公告）日：2012-02-08
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  公开号：US8445016B2

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