2-十二烷硫醇 | 14402-50-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 中文名称: 2-十二烷硫醇
• 英文名称: 2-dodecanethiol
• 英文别名: dodecane-2-thiol；Dodecan-2-thiol；sec-dodecyl mercaptan；2-dodecyl mercaptan；2-Mercapto-dodecan；2-Mercaptododecan
• CAS: 14402-50-7
• 化学式: C₁₂H₂₆S
• 分子量: 202.404
• InChiKey: UROXMPKAGAWKPP-UHFFFAOYSA-N

物化性质

• 熔点：
  -17°C
• 沸点：
  270.55°C (estimate)
• 密度：
  0.8366

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  13
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  2-十二烷硫醇 在 臭氧 作用下， 生成 十二烷-2-磺酸
  参考文献：
  名称：

  Asinger et al., Chemische Berichte, 1956, vol. 89, p. 1233,1236

  摘要：

  DOI：
• 作为产物：
  描述：

  2-溴十二烷 在 甲醇 、 sodium hydrogensulfide 、 异丙醇 作用下， 生成 2-十二烷硫醇
  参考文献：
  名称：

  Asinger et al., Chemische Berichte, 1956, vol. 89, p. 1233,1236

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING ESTER COMPOUND
  申请人：Imazeki Shigeaki

  公开号：US20100324314A1

  公开（公告）日：2010-12-23

  PROBLEM To provide an environmentally-friendly method for producing industrially an ester compound. SOLUTION The present invention is a method for producing an ester compound which comprises subjecting a carboxylic acid and an alcohol to dehydration-condensation reaction using an involatile acid catalyst and then removing the residual acid catalyst by bringing a weak basic substance into contact with the residual acid catalyst.

  问题提供一种生产工业酯化合物的环保方法。 解决方案是一种生产酯化合物的方法，包括将羧酸和醇经过脱水缩合反应，使用一种不挥发的酸催化剂，然后通过将弱碱性物质与残留的酸催化剂接触来去除残留的酸催化剂。
• Continuous photochemical production of high purity linear mercaptan and sulfide compositions
  申请人：Arkema Inc.

  公开号：US11161810B1

  公开（公告）日：2021-11-02

  Continuous photochemical production of high purity linear mercaptan and sulfide-containing compositions.

  连续光化学生产高纯度的直链硫醇和含硫化物的化合物。
• Iodine/iodide-containing hot melt coatable adhesive, methods and uses therefor
  申请人：Wang Danli

  公开号：US20050202070A1

  公开（公告）日：2005-09-15

  An iodine/iodide-containing hot melt coatable adhesive is provided. This adhesive is prepared by mixing iodine and an iodide salt, individually or in combination, with solubilizing liquids. The iodine and iodide salt are combined with a pre-adhesive composition in a hot melt mixer, with an iodine/iodide complexing agent being present in the mixture. The mixture is mixed at a temperature from about 130° C. to about 200° C. and sufficiently to form an iodine/iodide-containing hot melt coatable adhesive. Alternatively, the iodide may be generated in situ. The adhesive so prepared may be packaged for coating on a substrate at a later time, or may be immediately coated to form an adhesive composite. Adhesive composites, particularly surgical incise drapes, are provided incorporating this hot melt coatable adhesive.

  提供了一种含碘/碘化物的热熔涂层粘合剂。该粘合剂是通过将碘和碘化物单独或组合与溶解液混合而制备的。碘和碘化物与预粘合剂组合在热熔混合器中，其中碘/碘化物络合剂存在于混合物中。混合物在温度从约130℃到约200℃之间混合足够长的时间，从而形成含碘/碘化物的热熔涂层粘合剂。或者，碘化物可以在原位生成。这样制备的粘合剂可以打包，以便在以后涂覆在基材上，也可以立即涂覆以形成粘合剂复合材料。提供了包含这种热熔涂层粘合剂的粘合剂复合材料，特别是外科手术切口防护膜。
• Compounds having both peroxy and aliphatic azo groups
  申请人：Pennwalt Corporation

  公开号：US04088642A1

  公开（公告）日：1978-05-09

  I. Compounds having independent peroxidic (X) and aliphatic azo groups of the formula [(R-N.dbd.N-R').sub.m -X].sub.n Example: di-t-butylperoxy ester of cis-4,4'-azobis-(4-cyanovaleric acid). Ii. a method of making a block polymer where vinyl monomer is initiated sequentially to produce in one instance: a polymer having azo-carbon linkages present, which is then reacted with vinyl monomer under conditions to rupture the azo-carbon linkages, and in another instance: a polymer having peroxy-carbon linkages present, which is then reacted with vinyl monomer under conditions to rupture the peroxy carbon linkages.

  I. 具有独立过氧化物（X）和脂肪族偶氮基团的化合物，其化学式为[(R-N.dbd.N-R').sub.m -X].sub.n，例如：顺式4,4'-偶氮双（4-氰基戊酸）二-叔丁基过氧化酯。 II. 一种制备块状聚合物的方法，其中乙烯单体被按顺序引发以在一次反应中产生具有偶氮-碳键的聚合物，然后在条件下与乙烯单体反应以破坏偶氮-碳键，在另一次反应中产生具有过氧-碳键的聚合物，然后在条件下与乙烯单体反应以破坏过氧-碳键。
• HETEROCYCLIC INHIBITORS OF BACTERIAL PEPTIDYL TRNA HYDROLASE AND USES THEREOF
  申请人：Choi Soongyu

  公开号：US20100069380A1

  公开（公告）日：2010-03-18

  Provided herein are compounds that modulate the activity of a bacterial peptidyl tRNA hydrolase, including compositions and dosage forms comprising the compounds. Further provided herein are methods for screening and identifying compounds that modulate the activity of a bacterial peptidyl tRNA hydrolase. In particular, provided herein are assays for the identification of compounds that inhibit or reduce the activity of a bacterial peptidyl tRNA hydrolase. The methods provided herein provide a simple, sensitive assay for high-throughput screening of libraries of compounds to identify pharmaceutical leads useful for preventing, treating, and managing a bacterial infection or one or more symptoms thereof. Further provided herein are methods for preventing or inhibiting bacterial proliferation as well as methods for preventing, treating, and/or managing a bacterial infection using such compounds and compositions.

  本文提供了调节细菌肽基tRNA水解酶活性的化合物，包括含有这些化合物的组合物和剂型。此外，本文还提供了筛选和鉴定调节细菌肽基tRNA水解酶活性的化合物的方法。具体而言，本文提供了用于鉴定抑制或减少细菌肽基tRNA水解酶活性的化合物的测定方法。本文提供的方法为高通量筛选化合物库以识别有用于预防、治疗和管理细菌感染或其一种或多种症状的药物前导化合物提供了简单、敏感的测定方法。此外，本文还提供了使用这些化合物和组合物预防或抑制细菌增殖的方法，以及预防、治疗和/或管理细菌感染的方法。