2-萘胺-1,5-二磺酸 | 117-62-4

• 物质功能分类: 化学试剂 - 有机试剂 - 多环化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 2-萘胺-1,5-二磺酸
• 中文别名: 磺化吐氏酸；异构C酸；2-氨基-1,5-萘二磺酸；1,5酸；2-萘基胺-1,5-二磺酸
• 英文名称: 2-amino-1,5-naphthalenedisulfonic acid
• 英文别名: 2-aminonaphthalene-1,5-disulfonic acid；2-naphthylamine-1,5-disulfonic acid；sulpho tobias acid；1,5-disulfo-2-aminonaphthalene；2-amino-naphthalene-1,5-disulphonic acid
• CAS: 117-62-4
• 化学式: C₁₀H₉NO₆S₂
• mdl: MFCD00021512
• 分子量: 303.317
• InChiKey: YAIKCRUPEVOINQ-UHFFFAOYSA-N

物化性质

• 沸点：
  205.8°C (rough estimate)
• 密度：
  1.6329 (rough estimate)
• LogP：
  -1.85

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  152
• 氢给体数：
  3
• 氢受体数：
  7

安全信息

• 危险等级：
  8
• 危险品标志：
  C
• 安全说明：
  S26,S28A
• 危险类别码：
  R34
• WGK Germany：
  2
• 危险品运输编号：
  1759
• RTECS号：
  QJ6135000
• 海关编码：
  2921499090
• 包装等级：
  III
• 危险类别：
  8

SDS

Name:	2-Amino-1 5-Naphthalenedisulfonic Acid Tech. Material Safety Data Sheet
Synonym:	2-Naphthylamine-1,5-Disulfonic Acid
CAS:	117-62-4

Section 1 - Chemical Product MSDS Name:2-Amino-1 5-Naphthalenedisulfonic Acid Tech. Material Safety Data Sheet
Synonym:2-Naphthylamine-1,5-Disulfonic Acid

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
117-62-4	2-Amino-1,5-Naphthalenedisulfonic Acid	ca 100	204-201-6

Hazard Symbols: C
Risk Phrases: 34

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.
Inhalation:
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. May cause systemic effects.
Chronic:
Effects may be delayed.

---

Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

---

Section 7 - HANDLING and STORAGE
Handling:
Use only in a well-ventilated area. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Discard contaminated shoes.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 117-62-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: beige
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: > 300 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: soluble
Specific Gravity/Density:
Molecular Formula: C10H9NO6S2
Molecular Weight: 303.29

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 117-62-4: QJ6135000 LD50/LC50:
CAS# 117-62-4: Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild; Oral, rat: LD50 = 5430 mg/kg.
Carcinogenicity:
2-Amino-1,5-Naphthalenedisulfonic Acid - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

---

Section 12 - ECOLOGICAL INFORMATION

---

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

---

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: CORROSIVE SOLID, N.O.S.*
Hazard Class: 8
UN Number: 1759
Packing Group: III
IMO
Shipping Name: CORROSIVE SOLID, N.O.S.
Hazard Class: 8
UN Number: 1759
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE SOLID, N.O.S.
Hazard Class: 8
UN Number: 1759
Packing group: III

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with
plenty of water.
WGK (Water Danger/Protection)
CAS# 117-62-4: 1
Canada
CAS# 117-62-4 is listed on Canada's DSL List.
CAS# 117-62-4 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 117-62-4 is listed on the TSCA inventory.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

2-萘胺-1，5-二磺酸

2-萘胺-1，5-二磺酸是制造染料，特别是活性染料的重要中间体。其制备方法是在室温下将2-萘胺-1-磺酸（托拜厄斯酸）在发烟硫酸（“Oleum”）中进行磺化反应。“Oleum”的SO₃含量为15-30%（质量）。所得的反应混合物可通过稀释法沉淀出2-萘胺-1，5-二磺酸。然而，这种方法存在一些缺点：分离出来的2-萘胺-1，5-二磺酸会受到诸如2-萘胺和2-萘胺-5-磺酸等分解产物的污染，并以结晶形式沉淀，同时含有较高比例（约15-20%的质量）的硫酸。

为降低游离酸中硫酸含量，可以采用水洗或使用高度稀释的硫酸进行洗涤处理。但因为2-萘胺-1，5-二磺酸在水中和稀硫酸中的高溶解度，这种操作会带来较大的收率损失。已发现，通过在特定条件下对反应混合物进行稀释沉淀，可避免因游离酸形式沉淀而导致的问题。

用途

用作染料中间体。

类别

有毒物品。

毒性分级

低毒。

急性毒性（口服）

大鼠 LD₅₀: 5430毫克/公斤。

刺激数据

• 皮肤：兔子，500毫克/24小时 轻度
• 眼睛：兔子，20毫克/24小时 中度

可燃性危险特性

可燃；燃烧时产生有毒氮氧化物和硫氧化物烟雾。

储运特性

库房需通风、低温且干燥。

灭火剂

干粉、泡沫、砂土、二氧化碳或雾状水。

反应信息

• 作为反应物：
  描述：

  2-萘胺-1,5-二磺酸 在 氢氧化钾 、 水 作用下， 生成 2,5-二羟基-萘-1-磺酸
  参考文献：
  名称：

  Bucherer; Wahl, Journal fur praktische Chemie (Leipzig 1954), 1921, vol. <2>103, # 131, p. 146

  摘要：

  DOI：
• 作为产物：
  描述：

  2-萘胺-1-磺酸 在 硫酸 作用下， 生成 2-萘胺-1,5-二磺酸
  参考文献：
  名称：

  Bucherer; Wahl, Journal fur praktische Chemie (Leipzig 1954), 1921, vol. <2> 103, p. 135,136, 151, 153

  摘要：

  DOI：

文献信息

• Reactive black dye composition and method for dying fibers using the same
  申请人：Everlight Chemical Industrial Corporation

  公开号：US20190031881A1

  公开（公告）日：2019-01-31

  A reactive black dye composition is disclosed, which comprises: (A) a reactive blue dye represented by the following formula (I) or a salt thereof; and (B) a reactive red dye or a salt thereof, a reactive yellow dye or a salt thereof, or a combination thereof. Herein, R 11 , X 1 , X 2 , X 31 , X 41 and n are defined in the specification. In addition, a method for dying fibers using the aforesaid reactive black dye composition is also disclosed.

  揭示了一种反应性黑色染料组合物，包括：（A）由以下式（I）表示的反应性蓝色染料或其盐；以及（B）反应性红色染料或其盐、反应性黄色染料或其盐，或其组合物。在此，R11、X1、X2、X31、X41和n在规范中有定义。此外，还揭示了使用上述反应性黑色染料组合物染色纤维的方法。
• 一种喷墨印花活性红色染料及其制备方法和应用
  申请人：泰兴锦云染料有限公司

  公开号：CN113150576B

  公开（公告）日：2022-11-25

  本发明涉及一种喷墨印花活性红色染料及其制备方法和应用，属于精细化工领域。本发明提供的式I所示的活性红色染料，具有较高的溶解度，良好的固色率、色牢度，染色后稳定性高，色光鲜艳，可以广泛应用于棉、麻、人造棉纤维织品的浸染、轧染和喷墨印花中，而且生产成本低，可以大规模推广应用。
• 活性橙及其合成方法
  申请人：黄山普米特新材料有限公司

  公开号：CN106009769A

  公开（公告）日：2016-10-12

  本发明涉及化工技术领域，具体公开了一种活性橙，其化学结构式为：其中，n等于2或3；‑R为或本发明还公开了上述活性橙的合成方法，本发明公开的活性橙的色泽佳、溶解度高，且与现有技术的活性橙相比，其配置的溶液长时间接触空气后，溶液与空气接触的接触面未见固体结晶物，因此具有良好的保湿性，使用稳定性好。
• Environmental protection series of reactive dyestuffs and their use
  申请人：Chen Hsiao-San

  公开号：US20050203286A1

  公开（公告）日：2005-09-15

  An environmental protection reactive dyestuff of the following formula (I) is disclosed, wherein R 1 , R 2 , D, M are defined as in the specification. The dyestuff of the invention is distinguished by a high fixation and a very good build-up. It is distinguished also by a green environmental protection and a low salt, a low base, a high exhaustion, non-contain heavy metal and halogen atoms, and it has fiber-reactive properties and is very highly suitable for dyeing and printing of materials containing either cellulose fibers, such as cotton, synthetic cotton, hemp, and synthetic hemp, or amide containing fibers such as wool and nylon.

  揭示了以下化学式(I)的一种环保反应性染料，其中R1、R2、D、M的定义如规范中所述。该发明的染料具有高固定性和非常良好的建立性。它还具有绿色环保、低盐、低碱、高耗尽、不含重金属和卤原子的特点，具有纤维反应性能，非常适合于含有纤维素纤维（如棉花、合成棉、大麻和合成大麻）或含酰胺纤维（如羊毛和尼龙）的材料的染色和印花。
• REACTIVE DYE
  申请人：Chen Chien-Yu

  公开号：US20120264922A1

  公开（公告）日：2012-10-18

  A reactive dye is disclosed. The reactive dye has the structure of formula (I): wherein X, R 1 , R 2 , R 3 , n, Q 1 , Q 2 and (HO 3 S) 1-3 are defined in the specification. The reactive dye of the present invention has great build-up property, reproducibility and fastness.

  揭示了一种活性染料。该活性染料具有如下结构的化学式（I）：其中X、R1、R2、R3、n、Q1、Q2和（HO3S）1-3在说明书中有定义。本发明的活性染料具有良好的上浆性能、可重现性和牢固度。