N-(4-nitrophenyl)-N-(cyanomethyl)amine | 4686-21-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-nitrophenyl)-N-(cyanomethyl)amine
• 英文别名: N-Cyanmethyl-4-nitranilin；2-(4-Nitroanilino)acetonitrile
• CAS: 4686-21-9
• 化学式: C₈H₇N₃O₂
• 分子量: 177.162
• InChiKey: HGEQJRBNWNKPIA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  81.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  三甲基氰硅烷 、 1,3,5-tris(4-nitrophenyl)-1,3,5-hexahydrotriazine 在 四氯化钛 作用下， 以 二氯甲烷 为溶剂， 以90%的产率得到N-(4-nitrophenyl)-N-(cyanomethyl)amine
  参考文献：
  名称：

  TiCl₄induced N-Methyleneamine Equivalents: A New Route to Aminoacetonitriles

  摘要：

  TiCl4 induced N-methyleneamine equivalents from hexahydro-1,3,5-triazines or N-(methoxymethyl)amines were reacted with trimethylsilyl cyanide to give aminoacetonitriles in 40-90% yield.

  DOI：

  10.1080/00397919108020806

文献信息

• Copper-Catalyzed Three- Five- or Seven-Component Coupling Reactions: The Selective Synthesis of Cyanomethylamines, N,N-Bis(Cyanomethyl)Amines and N,N'-Bis(Cyanomethyl)Methylenediamines Based on a Strecker-Type Synthesis
  作者：Norio Sakai、Nobuaki Takahashi、Daiki Inoda、Reiko Ikeda、Takeo Konakahara

  DOI：10.3390/molecules181012488

  日期：——

  We have demonstrated that a cooperative catalytic system comprised of CuCl and Cu(OTf)2 could be used to effectively catalyse the three-, five- and seven-component coupling reactions of aliphatic or aromatic amines, formaldehyde, and trimethylsilyl cyanide (TMSCN), and selectively produce in good yields the corresponding cyanomethylamines, N,N-bis(cyanomethyl)amines and N,N'-bis(cyanomethyl)methylenediamines.

  我们已经证明，由CuCl和Cu(OTf)2组成的协同催化系统可以有效催化脂肪族或芳香族胺、甲醛和三甲基硅基氰化物（TMSCN）的三元、五元和七元偶联反应，并选择性地以良好的产率生成相应的氰甲基胺、N,N-双（氰甲基）胺和N,N'-双（氰甲基）亚甲基二胺。
• Cyclic ether copolymer, coating resin composition, optical devices, and process for production of the devices
  申请人：Araki Takayuki

  公开号：US20060189788A1

  公开（公告）日：2006-08-24

  This invention provides a cyclic ether copolymer such as a cyclic ether copolymer excellent in solubility in solvents and easy to form uniform thin films therefrom. The present invention relates to a cyclic ether copolymer obtained from a 1,3-dioxole ring structure-containing compound represented by the following general formula (I) and an ethylenically unsaturated monomer: (wherein R 1 and R 2 are the same or different and each represents F, H, Cl or a perfluoroalkyl group containing 1 to 5 carbon atoms and X 1 and X 2 are the same or different and each represents F, H, Cl or —OR 3 , and R 3 represents a perfluoroalkyl group containing 1 to 5 carbon atoms, provided that at least one of R 1 and R 2 is F or a perfluoroalkyl group containing 1 to 5 carbon atoms), which compolymer has a glass transition point of 100 to 135° C. and an intrinsic viscosity of 0.01 to 0.4 dl/g as determined at 35° C. in perfluoro-2-butyltetrahydrofuran.

  本发明提供了一种环醚共聚物，如在溶剂中溶解性极佳且易于形成均匀薄膜的环醚共聚物。本发明涉及一种环醚共聚物，由下式通式（I）表示的含 1，3-二恶茂环结构的化合物和乙烯基不饱和单体得到： (其中 R 1 和 R 2 相同或不同，各自代表 F、H、Cl 或含有 1 至 5 个碳原子的全氟烷基，以及 X 1 和 X 2 相同或不同，且各自代表 F、H、Cl 或 -OR 3 和 R 3 代表含有 1 至 5 个碳原子的全氟烷基，条件是 R 1 和 R 2 是 F 或含有 1 至 5 个碳原子的全氟烷基），该共聚物的玻璃化转变点为 100 至 135 摄氏度，在 35 摄氏度的全氟-2-丁基四氢呋喃中测定的固有粘度为 0.01 至 0.4 分升/克。
• 一种胺的氰甲基化方法
  申请人：沈阳化工大学

  公开号：CN117342978A

  公开（公告）日：2024-01-05

  氰甲基胺的结构存在于许多生物活性分子和天然化合物中，是许多农药和医药合成的关键中间体。本发明提供了一种胺的氰甲基化方法。该方法使用胺与甲醛、三甲基氰硅烷进行Strecker反应生成相应的氰甲基化产物，得到的产物收率高、条件温和，适合工业化生产，具有良好的应用前景。
• HA, HYUN-JOON;NAM, GONG-SIL;PARK, KYONG PAE, SYNTH. COMMUN., 21,(1991) N, C. 155-160
  作者：HA, HYUN-JOON、NAM, GONG-SIL、PARK, KYONG PAE

  DOI：——

  日期：——
• Nonlinear optical materials comprising fluorine-containing polymer
  申请人：Araki Takayuki

  公开号：US20050004253A1

  公开（公告）日：2005-01-06

  There is provided a fluorine-containing resin composition which is used for nonlinear optical material and comprises (I) a fluorine-containing prepolymer and (II) an organic compound exhibiting a second- or higher-order nonlinear optical effect, in which the fluorine-containing prepolymer (I): (1) is a non-crystalline polymer having a fluorine content of not less than 25% and (2) has a carbon-carbon double bond in a polymer side chain or at an end of a polymer trunk chain and also there is provided a nonlinear optical waveguide device produced from the fluorine-containing resin composition. A suitable nonlinear optical material having a stable structure with a nonlinear substance is produced, and an excellent nonlinear optical waveguide device is produced by relatively simple steps while maintaining transparency in a near infrared region.