4-(1-methoxyethyl)benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(1-methoxyethyl)benzoic acid
• 英文别名: (+)-4-(1-methoxyethyl)benzoic acid；(-)-4-(1-Methoxyethyl)benzoic acid
• 化学式: C₁₀H₁₂O₃
• 分子量: 180.203
• InChiKey: BNUIDCTVAUCIEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-(氨基甲基)-4,6-二甲基-1,2-二氢吡啶-2-酮 、 4-(1-methoxyethyl)benzoic acid 在 三乙胺 、 Methanaminium,N-[(dimethylamino)(3H-1,2,3-triazolo[4,5-b]pyridin-3-yloxy)methylene]-N-methyl-, hexafluorophosphate(1-) 作用下， 以 二氯甲烷 为溶剂， 以23%的产率得到N-((2-hydroxy-4,6-dimethylpyridin-3-yl)methyl)-4-(1-methoxyethyl)benzamide
  参考文献：
  名称：

  MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

  摘要：

  这里提供了用于调节甲基修饰酶的药剂、组合物及其用途。

  公开号：

  US20150315148A1
• 作为产物：
  描述：

  4-(1-羟基乙基)苯甲酸甲酯 在 水 、 溴化铋 、 lithium hydroxide 作用下， 以 甲醇 、 四氯化碳 为溶剂， 反应 24.5h， 生成 4-(1-methoxyethyl)benzoic acid
  参考文献：
  名称：

  [EN] MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
  [FR] MODULATEURS D'ENZYMES DE MODIFICATION PAR MÉTHYLATION, COMPOSITIONS ET UTILISATIONS ASSOCIÉES

  摘要：

  公开号：

  WO2013075084A8

文献信息

• DIELS-ALDER REACTIONS CATALYZED BY LEWIS ACID CONTAINING SOLIDS: RENEWABLE PRODUCTION OF BIO-PLASTICS
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20140364631A1

  公开（公告）日：2014-12-11

  The present disclosure is related to silica-based Lewis acid catalysts, being essentially devoid of strong Brønsted acid character, and their ability to effect the [4+2] cycloaddition and dehydrative aromatization of dienes and dienophiles containing oxygenated substituents to form substituted benzene products. In some embodiments, the processes comprise contacting biomass-derived substrates with ethylene to form terephthalic acid and its derivatives.

  本公开涉及基于硅的路易斯酸催化剂，基本上不具有强布朗斯特酸特性，以及它们在作用[4+2]环加成和脱水芳构化二烯和二烯酰基含氧取代基的产物形成取代苯方面的能力。在某些实施例中，这些过程包括将生物质衍生底物与乙烯接触，形成对苯二甲酸及其衍生物。
• Optically active aromatic carboxylic acid derivatives and process for
  申请人：Sumitomo Chemical Company, Limited

  公开号：US05019298A1

  公开（公告）日：1991-05-28

  Disclosed are optically active aromatic carboxylic acid derivatives represented by the formula (I): ##STR1## (wherein R.sub.2 represents an alkoxyalkyl group having 1 to 20 carbon atoms or an alkyl group having 1 to 20 carbon atoms, which alkyl group may be substituted with a halogen atom; represents a number of 1 or 2; m represents a number of 0 or 1; and * indicates asymmetric carbon atom) and a process for producing such derivatives through the following reaction steps: ##STR2## The optically active aromatic carboxylic acid derivatives represented by the above-described formula (I) are useful as a liquid crystal material and can be also utilized as an intermeidate for the preparation of pharmaceuticals, agricultural chemicals and the like.

  本发明涉及一种光学活性芳香羧酸衍生物，其化学式为(I)：##STR1## 其中，R.sub.2代表具有1至20个碳原子的烷氧烷基或具有1至20个碳原子的烷基，该烷基可以被卤素原子取代；表示数字1或2；m表示数字0或1；*表示不对称碳原子。本发明还涉及通过以下反应步骤制备这种衍生物的方法：##STR2## 上述化学式(I)所表示的光学活性芳香羧酸衍生物可用作液晶材料，并可用作制备药物、农药等中间体。
• Optically active ether derivatives, preparation process therefor, liquid
  申请人：Sumitomo Chemical Company, Limited

  公开号：US05013479A1

  公开（公告）日：1991-05-07

  Disclosed are herein optically active ether derivatives represented by the formula (I): ##STR1## (wherein X represents --COO-- or --OCO--; A represents an alkyl or alkoxyl group having 3 to 15 carbon atoms; R represents an alkyl or alkyloxyalkyl group having 1 to 20 carbon atoms; l and m each represents a number of 1 to 2; and * indicates an asymmetric carbon atom), preparation processes therefor, liquid crystal materials containing such ether derivatives as active ingredient, and an optical switching element using said liquid crystal materials as liquid crystal element.

  本发明涉及一种光学活性的醚衍生物，其化学式为(I)：##STR1##（其中，X代表--COO--或--OCO--；A代表具有3到15个碳原子的烷基或烷氧基；R代表具有1到20个碳原子的烷基或烷氧基烷基；l和m分别表示1到2的数字；*表示不对称碳原子），以及其制备方法，含有该醚衍生物作为活性成分的液晶材料，以及使用所述液晶材料作为液晶元件的光学开关元件。
• A process for the sequential polymerization of ethylene and propylene
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0176133A2

  公开（公告）日：1986-04-02

  A continuous process for sequential polymerization of ethylene and propylene by first homopolymerizing propylene in a liquid medium comprising propylene monomer as major constituent and in the presence of a magnesiumchloride and titanium containing catalyst and then copolymerizing ethylene and propylene in the presence of a liquid medium, each of these reactions being effected in a stirred tank reactor, characterized in that the homopolymer slurry is transferred from the homopolymerization reactor to the copolymerization reactor through a pipe line reactor in which the residence time of the homopolymer slurry is at least 2.5 min.

  一种乙烯和丙烯顺序聚合的连续工艺，首先在以丙烯单体为主要成分并含有氯化镁和钛的催化剂的液体介质中均聚丙烯，然后在液体介质中共聚乙烯和丙烯、上述反应均在搅拌罐反应器中进行，其特征在于均聚物浆料通过管线反应器从均聚反应器转移到共聚反应器，均聚物浆料在管线反应器中的停留时间至少为 2.5 分钟。
• Optically active aromatic carboxylic acid derivatives and process for producing the same
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0289307A2

  公开（公告）日：1988-11-02

  Disclosed are optically active aromatic carboxylic acid derivatives represented by the formula (I): (wherein R2 represents an alkoxyalkyl group having 1 to 20 carbon atoms or an alkyl group having 1 to 20 carbon atoms, which alkyl group may be substituted with a halogen atom; represents a number of 1 or 2; m represents a number of 0 or 1; and * indicates asymmetric carbon atom) and a process for producing such derivatives through the following reaction steps: The optically active aromatic carboxylic acid derivatives represented by the above-described formula (I) are useful as a liquid crystal material and can be also utilized as an intermediate for the preparation of pharmaceuticals, agricultural chemicals and the like.

  本发明公开了由式(I)代表的具有光学活性的芳香族羧酸衍生物： (其中 R2 代表具有 1 至 20 个碳原子的烷氧基烷基或具有 1 至 20 个碳原子的烷基，该烷基可被卤素原子取代；代表的数目为 1 或 2；m 代表的数目为 0 或 1；* 表示不对称碳原子）以及通过以下反应步骤生产此类衍生物的工艺： 以上述式（I）为代表的光学活性芳香族羧酸衍生物可用作液晶材料，也可用作制备药物、农药等的中间体。