2,3-epoxypropyl m-nitrobenzoate | 95115-20-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3-epoxypropyl m-nitrobenzoate
• 英文别名: Oxiran-2-ylmethyl 3-nitrobenzoate
• CAS: 95115-20-1
• 化学式: C₁₀H₉NO₅
• 分子量: 223.185
• InChiKey: XUMFIVGBGGPDJW-UHFFFAOYSA-N

物化性质

• 熔点：
  78 °C
• 沸点：
  365.8±12.0 °C(Predicted)
• 密度：
  1.399±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  84.6
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,3-epoxypropyl m-nitrobenzoate 在 Lindlar's catalyst 氢气 作用下， 以 甲醇 、 异丙醇 为溶剂， 反应 32.0h， 生成 (3-aminophenyl)-N-[(2,3-dihydroxypropyl)piperidyl]formamide
  参考文献：
  名称：

  Incorporation of carbohydrates and peptides into large triazine-based screening libraries using automated parallel synthesis

  摘要：

  A procedure for the sequential, selective derivatization of cyanuric chloride that allows for the incorporation of carbohydrates and peptides has been elucidated. As a result, large combinatorial arrays of individual derivatives, over 40,000 in all, have been produced in 50 mu mole quantities using automated parallel solution phase synthesis. The use of this technology in a search for protease inhibitors, glycopeptide surrogates and other bioactive compound classes will also be discussed. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00134-3
• 作为产物：
  描述：

  缩水甘油 、 间硝基苯甲酰氯 在 三乙胺 作用下， 以 甲苯 为溶剂， 反应 15.0h， 生成 2,3-epoxypropyl m-nitrobenzoate
  参考文献：
  名称：

  Incorporation of carbohydrates and peptides into large triazine-based screening libraries using automated parallel synthesis

  摘要：

  A procedure for the sequential, selective derivatization of cyanuric chloride that allows for the incorporation of carbohydrates and peptides has been elucidated. As a result, large combinatorial arrays of individual derivatives, over 40,000 in all, have been produced in 50 mu mole quantities using automated parallel solution phase synthesis. The use of this technology in a search for protease inhibitors, glycopeptide surrogates and other bioactive compound classes will also be discussed. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00134-3

文献信息

• Methods and compositions for servicing fluids comprising derivatized cellulose gelling agents
  申请人：Hanes E. Robert

  公开号：US20060196662A1

  公开（公告）日：2006-09-07

  One embodiment of the present invention provides methods of treating a portion of a subterranean formation, comprising providing a treatment fluid comprising a derivatized cellulose gelling agent wherein the derivatized cellulose gelling agent is made by reacting cellulose with an electrophilic agent to form a 1,3-cis diol or an alpha carboxylic acid; and, placing the treatment fluid in the portion of the subterranean formation. Another embodiment of the present invention provides methods of derivatizing cellulose, comprising reacting cellulose with an electrophilic agent to form a 1,3-cis diol or an alpha carboxylic acid. Another embodiment of the present invention provides crosslinkable treatment fluids for use in subterranean formations comprising a derivatized cellulose gelling agent wherein the derivatized cellulose gelling agent comprises a cellulose that has been derivatized to comprise an alpha carboxylic acid or a compound comprising a 1,3-cis diol moiety.

  本发明的一个实施例提供了处理部分地下地层的方法，包括提供一种处理液，该处理液包含一种衍生化纤维素胶凝剂，其中衍生化纤维素胶凝剂是通过纤维素与亲电剂反应形成1,3-顺式二元醇或α-羧酸而制成的；以及，将处理液置于部分地下地层中。本发明的另一个实施方案提供了衍生化纤维素的方法，包括使纤维素与亲电剂反应形成 1,3-顺式二元醇或α-羧酸。本发明的另一个实施方案提供了用于地下地层的可交联处理液，该处理液包含一种衍生化纤维素胶凝剂，其中衍生化纤维素胶凝剂包含一种纤维素，该纤维素已经衍生化，包含一种α-羧酸或一种包含1,3-顺式二元醇分子的化合物。
• Klebanov, M. S.; Kir'yazev, F. Yu.; Chervinskii, A. Yu., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, # 11, p. 2193 - 2196
  作者：Klebanov, M. S.、Kir'yazev, F. Yu.、Chervinskii, A. Yu.、Shologon, I. M.

  DOI：——

  日期：——
• KLEBANOV, M. S.;KIRYAZEV, F. YU.;CHERVINSKIJ, A. YU.;SHOLOGON, I. M., ZH. ORGAN. XIMII, 1984, 20, N 11, 2407-2411
  作者：KLEBANOV, M. S.、KIRYAZEV, F. YU.、CHERVINSKIJ, A. YU.、SHOLOGON, I. M.

  DOI：——

  日期：——
• Incorporation of carbohydrates and peptides into large triazine-based screening libraries using automated parallel synthesis
  作者：Gary R. Gustafson、Carmen M. Baldino、Mary-Margaret E. O'Donnell、Adrian Sheldon、Robert J. Tarsa、Christopher J. Verni、David L. Coffen

  DOI：10.1016/s0040-4020(98)00134-3

  日期：1998.4

  A procedure for the sequential, selective derivatization of cyanuric chloride that allows for the incorporation of carbohydrates and peptides has been elucidated. As a result, large combinatorial arrays of individual derivatives, over 40,000 in all, have been produced in 50 mu mole quantities using automated parallel solution phase synthesis. The use of this technology in a search for protease inhibitors, glycopeptide surrogates and other bioactive compound classes will also be discussed. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.