methoxy-diphenyl-acetic acid | 7475-61-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methoxy-diphenyl-acetic acid
• 英文别名: 2-methoxy-2,2-diphenylacetic acid；methoxydiphenylacetic acid；Methoxy-diphenyl-essigsaeure；α-Methoxy-diphenylessigsaeuer；Methylaetherbenzilsaeure；α-Methoxy-α,α-diphenylessigsaeure
• CAS: 7475-61-8
• 化学式: C₁₅H₁₄O₃
• 分子量: 242.274
• InChiKey: YNDNIPMGZASSRG-UHFFFAOYSA-N

物化性质

• 熔点：
  100 °C
• 沸点：
  377.8±37.0 °C(Predicted)
• 密度：
  1.189±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  methoxy-diphenyl-acetic acid 在 silver hexafluoroantimonate 、 2,6-二甲基苯甲酸 、 dichloro[1,3-di(ethoxycarbonyl)-2,4,5-trimethylcyclopentadienyl]rhodium(III) dimer 、 copper(II) acetate monohydrate 、 potassium carbonate 作用下， 以 二乙二醇二甲醚 为溶剂， 反应 20.0h， 以62%的产率得到9-methoxyfluorene
  参考文献：
  名称：

  Rhodium- and Iridium-Catalyzed Dehydrogenative Cyclization through Double C–H Bond Cleavages To Produce Fluorene Derivatives

  摘要：

  The rhodium-catalyzed cyclization of a series of 2,2-diarylalkanoic acids in the presence of copper acetate as an oxidant smoothly proceeded through double C-H bond cleavages and subsequent decarboxylation to produce the corresponding fluorene derivatives. The direct cyclization of triarylmethanols also took place efficiently by using an iridium catalyst in place of the rhodium, while the hydroxy function was still intact.

  DOI：

  10.1021/jo4000465
• 作为产物：
  描述：

  苯甲酮二甲基缩酮 在 乙醚 、 氢化钾 作用下， 生成 methoxy-diphenyl-acetic acid
  参考文献：
  名称：

  Ziegler; Thielmann, Chemische Berichte, 1923, vol. 56, p. 1741

  摘要：

  DOI：

文献信息

• HERBICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES OF TETRAHYDRO- AND DIHYDROFURANCARBOXAMIDES
  申请人：BAYER AKTIENGESELLSCHAFT

  公开号：US20200216403A1

  公开（公告）日：2020-07-09

  The invention relates to 3-phenylisoxazoline-5-carboxamides of tetrahydro and dihydrofuran carboxamides of general formula (I) and to their agrochemically compatible salts (I) as well as to the use thereof in the field of plant protection.

  这项发明涉及一般式(I)的3-苯基异噁唑啉-5-羧酰胺以及其农药兼容盐(I)，以及它们在植物保护领域中的应用。
• Medicaments for inhalation comprising an anticholinergic and a betamimetic
  申请人：Meade John Montague Christopher

  公开号：US20050025718A1

  公开（公告）日：2005-02-03

  A pharmaceutical composition comprising an anticholinergic and a betamimetic of formula 2 optionally together with a pharmaceutically acceptable excipient, the anticholinergic and the betamimetic optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of asthma, COPD, or other inflammatory or obstructive respiratory complaints.

  一种包括抗胆碱药物和公式2的β-受体激动剂的药物组合物，可选地与药学上可接受的赋形剂一起使用，抗胆碱药物和β-受体激动剂可选地以其对映体、对映体混合物、混合物、溶剂化合物或水合物的形式存在，以及用于制备它们的方法，以及它们在治疗哮喘、COPD或其他炎症性或阻塞性呼吸疾病中的用途。
• SUBSTITUTED 3-HETEROARYLOXY-1H-PYRAZOLES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US20200181117A1

  公开（公告）日：2020-06-11

  A substituted 3-heteroaryloxy-1H-pyrazole of the general formula (I) or salt thereof Substituted 3-heteroaryloxy-1H-pyrazoles of the general formula (I) are described, as is their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants described. The present invention also relates to herbicidal and/or plant growth-regulating compositions comprising one or more compounds of the general formula (I).

  通用式（I）的取代3-杂环氧基-1H-吡唑或其盐已被描述。 通用式（I）的取代3-杂环氧基-1H-吡唑被描述， 以及它们作为除草剂的用途，特别是用于控制作物中的阔叶杂草和/或杂草草，以及作为植物生长调节剂，影响作物生长的用途。 本发明还涉及包含一个或多个通用式（I）化合物的除草剂和/或植物生长调节剂组合物。
• SUBSTITUTED 2-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS
  申请人：Bayer Aktiengesellschaft

  公开号：US20210276974A1

  公开（公告）日：2021-09-09

  Substituted 2-heteroaryloxypyridines and salts thereof and use thereof as herbicidal active substances Substituted 2-heteroaryloxypyridines of the general formula (I) are described, and their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The present invention further relates to herbicidal and/or plant growth-regulating compositions comprising one or more compounds of the general formula (I).

  2-杂环氧基吡啶及其盐的替代物及其作为除草活性物质的用途被描述，一般式(I)的2-杂环氧基吡啶的替代物被描述，并且它们作为除草剂的用途，特别是用于控制作物中的阔叶杂草和/或杂草草本植物，或者作为植物生长调节剂，以影响作物的生长。本发明还涉及包含一种或多种一般式(I)化合物的除草剂和/或植物生长调节剂组合物。
• Herbicidal Compounds Based on N-Azinyl-N-Phenylsulfonylureas
  申请人：Rosinger Christoph Hugh

  公开号：US20110105324A1

  公开（公告）日：2011-05-05

  What is described are compounds of the formula (I) in which the respective substituents have the meanings given in the description. The compounds of the formula (I) can be used as herbicides and plant growth regulators.

  描述的是具有式(I)的化合物，其中各自的取代基具有说明书中给出的含义。式(I)的化合物可以用作除草剂和植物生长调节剂。