4-(4'-pentyl-bicyclohexyl-4-yl)-bromobenzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4'-pentyl-bicyclohexyl-4-yl)-bromobenzene
• 英文别名: 1-Bromo-4-(4'-pentyl[1,1'-bicyclohexyl]-4-yl)benzene；1-bromo-4-[4-(4-pentylcyclohexyl)cyclohexyl]benzene
• 化学式: C₂₃H₃₅Br
• 分子量: 391.435
• InChiKey: WFQXECMAXWKLPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  4-(4'-pentyl-bicyclohexyl-4-yl)-bromobenzene 在 正丁基锂 、 platinum on carbon 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 8.0h， 生成 3-[Dimethyl-[4-[4-(4-pentylcyclohexyl)cyclohexyl]phenyl]silyl]propan-1-ol
  参考文献：
  名称：

  SILICON-CONTAINING COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY USING THE SAME

  摘要：

  提供一种含硅化合物、液晶组合物和使用该含硅化合物的液晶显示器。该含硅化合物具有由式（I）表示的结构： 其中K、R1、A1、A2、A3、A4、Z1、Z2、Z3、L7、L8、L9、X6、X7、n1、n2、n3和n4如规范中定义。

  公开号：

  US20190338190A1

文献信息

• A rapid and efficient catalysis system for the synthesis of 4-vinylbiphenyl derivatives
  作者：Xiaowei Ma、Yan Liu、Ping Liu、Jianwei Xie、Bin Dai、Zhiyong Liu

  DOI：10.1002/aoc.3045

  日期：2013.12

  A series of 4‐vinylbiphenyl derivatives were synthesized by Pd(OAc)2/PCy3‐catalyzed Suzuki–Miyaura reaction in the presence of K3PO4.3H2O as base in toluene at 80°C for only 10–30 min, and the corresponding products achieved 65–98% yields. According to this efficient C―C bond‐forming method, the obtained yields of 4‐vinylbiphenyl liquid crystal compounds were up to 92–96%. Copyright © 2013 John Wiley

  在甲苯中以K 3 PO 4 .3H 2 O为碱的情况下，在80°C下仅10-30分钟的时间内，通过Pd（OAc）2 / PCy 3催化的Suzuki-Miyaura反应合成了一系列4-乙烯基联苯衍生物。，相应的产品可达到65-98％的收率。根据这种有效的CC键形成方法，获得的4-乙烯基联苯液晶化合物的产率高达92-96％。版权所有©2013 John Wiley＆Sons，Ltd.
• Synthesis of 4-Vinylbiphenyl Derivatives by Pd(II)-1,2-Diamino-cyclohexane Complex Catalyzed Suzuki-Miyaura Reaction
  作者：Y. Liu、X.W. Ma、P. Liu、J.W. Xie、B. Dai

  DOI：10.14233/ajchem.2014.16972

  日期：——

  A series of 4-vinylbiphenyl derivatives were synthesized by Pd(II)-1,2-diaminocyclohexane complex catalyzed Suzuki-Miyaura reactions in the presence of K3PO4·3H2O as base in toluene at 80 °C and the corresponding products achieved 39-95 % yields. According to this efficient C-C bond-forming method, the obtained yields of 4-vinylbiphenyl liquid crystal compounds were up to 89 %.

  一系列4-乙烯基联苯衍生物通过Pd(II)-1,2-二氨基环己烷复合催化的铃木-宫浦反应合成，在80℃的甲苯中以K3PO4·3H2O作为碱，得到的产物收率为39-95%。根据这一高效的C-C键形成方法，获得的4-乙烯基联苯液晶化合物的收率高达89%。
• Metallomicelles of palladium(II) complexes as efficient catalysts for the Suzuki-Miyaura reaction in neat water
  作者：Yan Liu、Xiaowei Ma、Jianwei Xie、Ping Liu、Bin Dai、Ren He

  DOI：10.1002/aoc.3021

  日期：2013.8

  Metallomicelles of palladium(II) complex 4 are found to be an efficient catalyst for Suzuki–Miyaura reactions of aryl bromides substituted with a long alkyl chain and arylboronic acids at 80 °C in neat water. The reactions proceed smoothly to generate the corresponding biaryl compounds in moderate to excellent yields. Various biphenyl derivatives were successfully obtained by complex 4 catalysis of the Suzuki–Miyaura

  钯（II）配合物4的金属硅化物是纯水中80℃下被长烷基链取代的芳基溴化物和芳基硼​​酸的Suzuki-Miyaura反应的有效催化剂。反应平稳进行，以中等至优异的产率产生相应的联芳基化合物。在纯净水中不存在任何表面活性剂的情况下，通过Suzuki-Miyaura反应的复合物4催化成功地获得了各种联苯衍生物。版权所有©2013 John Wiley＆Sons，Ltd.
• Bis(imino)pyridine palladium(II) complexes: Synthesis, structure and catalytic activity
  作者：Ping Liu、Li Zhou、Xiaogang Li、Ren He

  DOI：10.1016/j.jorganchem.2009.03.021

  日期：2009.6

  Bis(imino)pyridine palladium(II) complexes 3–6 were synthesized by two different methods. The structure of complexes 3 and 4 has been confirmed by X-ray structure analysis. The catalytic studies show that bis(imino)pyridine palladium(II) complexes are highly efficient catalysts in the Suzuki–Miyaura reaction and the complex 4 was used to catalyze the synthesis of fluorinated liquid crystalline compounds

  双（亚氨基）吡啶钯（II）络合物3 - 6由两个不同的方法来合成。配合物3和4的结构已经通过X射线结构分析得到证实。催化研究表明，双（亚氨基）吡啶钯（II）配合物是Suzuki-Miyaura反应中的高效催化剂，配合物4用于通过Suzuki偶联反应催化氟化液晶化合物的合成。
• Efficient synthesis of fluorinated biphenyl derivatives via Pd-catalyzed Suzuki coupling reactions in aqueous solvents at room temperature
  作者：Mengping Guo、Fangfang Jian、Ren He

  DOI：10.1016/j.jfluchem.2005.09.003

  日期：2006.2

  A variety of fluorinated biphenyl derivatives were obtained in good yields in aqueous solvents at room temperature by Suzuki coupling reaction of aryl bromides and aryl boronic acid in the presence of high activity catalyst—some air-stable hemilabile PO coordinated cyclopalladated complexes. The structures of above catalysts were characterized by element analyses, IR, 1H NMR, 13C NMR and 31P NMR.

  在高活性催化剂的存在下，通过芳烃溴化物和芳基硼​​酸的Suzuki偶联反应，在室温下在水性溶剂中以高收率获得了多种氟化联苯衍生物。一些空气稳定的半不稳定的PO配位的环钯配合物。通过元素分析，IR，1 H NMR，13 C NMR和31 P NMR表征上述催化剂的结构。