1,7-bis(2-(hydrazinocarbonyl)phenyl)-1,4,7-trioxaheptane | 847661-05-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,7-bis(2-(hydrazinocarbonyl)phenyl)-1,4,7-trioxaheptane
• 英文别名: 2,2'-[Oxybis(ethane-2,1-diyloxy)]dibenzohydrazide；2-[2-[2-[2-(hydrazinecarbonyl)phenoxy]ethoxy]ethoxy]benzohydrazide
• CAS: 847661-05-6
• 化学式: C₁₈H₂₂N₄O₅
• 分子量: 374.396
• InChiKey: LCGHSSVREQIFGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  27
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  138
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  copper(II) choride dihydrate 、 1,7-bis(2-(hydrazinocarbonyl)phenyl)-1,4,7-trioxaheptane 在 acetate buffer 作用下， 以 水 、 乙腈 为溶剂， 生成 Cu⁽²⁺⁾*(NH₂NHC(O)C₆H₄OCH₂CH₂)2O=Cu((NH₂NHC(O)C₆H₄OCH₂CH₂)2O)⁽²⁺⁾
  参考文献：
  名称：

  On the relationship between the luminescence of heterometallic terbium-copper-podand complexes and the ligand structure

  摘要：

  The formation conditions and luminescence of heterometallic Tb-Cu complexes with structurally similar podands containing different numbers of oxymethylene fragments were studied (n = 2-7). The component ratio in mono- and different-metal complexes were 1 : 1 and 1 : 1 : 1, respectively. The possibility of complex formation for the carbonyl and enol forms was estimated by molecular mechanics. The results were in good agreement with experimental data. The most pronounced enhancement of luminescence intensity of Tb(III) ions in heterometallic Tb-Cu complexes was observed for podands containing two and three oxymethylene fragments (L1 and L2, respectively) and the probability of complex formation with these podands is higher than with the podands containing four to seven oxymethylene fragments (L3-L5).

  DOI：

  10.1134/s0036023609070079
• 作为产物：
  描述：

  1,7-bis(2-(methoxycarbonyl)phenyl)-1,4,7-trioxaheptane 在 一水合肼 、 sodium carbonate 作用下， 以 乙醇 、 水 为溶剂， 反应 12.0h， 以99%的产率得到1,7-bis(2-(hydrazinocarbonyl)phenyl)-1,4,7-trioxaheptane
  参考文献：
  名称：

  用于识别重金属离子的动态组合库†

  摘要：

  我们目前使用of动态组合库（DCL）来识别对碱土金属离子比碱金属离子具有选择性的大环受体。特别是，有毒重金属离子Sr 2+和Ba 2+会引起DCLs的特征变化。分离出四个大环，并通过LCMS，HRMS，NMR和X射线晶体学进行表征。通过紫外-可见光谱的结合研究证实了在DCL中观察到的选择性。

  DOI：

  10.1039/c1ob05976a

文献信息

• The role of copper ions in Tb(III) luminescence sensitization in heterometallic complexes with podands
  作者：Yu. P. Golovach、A. V. Kiriyak、L. N. Ognichenko、S. S. Basok、I. P. Kovalevskaya、I. M. Rakipov、V. E. Kuz’min、S. B. Meshkova

  DOI：10.1134/s0036023616070068

  日期：2016.7

  It has been demonstrated that copper-induced terbium(III) luminescence sensitization in heterometallic complexes with hydrazine-containing podands is caused by the ligand ring closure and joint coordination of both metal ions to the carbonyl oxygen atoms as well as, mainly, by the reduction with the hydrazine substituents of Cu(II) to Cu(I), which is able to sensitize terbium luminescence.