4-Methyl-methyl phenyl sulfoxide | 132260-80-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Methyl-methyl phenyl sulfoxide
• 英文别名: 1-ethyl-4-(4-ethylphenyl)sulfinylbenzene
• CAS: 132260-80-1
• 化学式: C₁₆H₁₈OS
• 分子量: 258.384
• InChiKey: BNZXXGYQOJEXFD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  36.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Methyl-methyl phenyl sulfoxide 在 ruthenium(III) chloride trihydrate 、 silver carbonate 、 三氟乙酸 作用下， 反应 20.0h， 以84%的产率得到2,8-diethyldibenzo[b,d]thiophene
  参考文献：
  名称：

  一锅铑催化连续脱氢/脱氧：从二芳基亚砜中高效合成二苯并噻吩衍生物

  摘要：

  通过二芳基亚砜的一锅式分子内交叉脱氢偶联反应，然后用 Rh/Ag 催化体系脱氧，建立了一种合成二苯并噻吩衍生物的新策略。获得的产率从好到极好（高达 96%），因此使所描述的协议成为构建二苯并噻吩化合物的有吸引力的选择。

  DOI：

  10.1002/ejoc.201501075
• 作为产物：
  描述：

  乙基苯 在 五氟化锑 、 氟磺酸 作用下， 以 1,1,2-三氯三氟乙烷（CFC-113） 为溶剂， 以90%的产率得到4-Methyl-methyl phenyl sulfoxide
  参考文献：
  名称：

  Reaction of simple arenes with FSO3H.cntdot.SbF5/SO2: one-pot synthesis of aromatic sulfoxides. Mechanistic aspects and synthetic utility

  摘要：

  In a simple one-pot reaction, mono-, di-, tri-, and polyalkylbenzenes, isomeric alkylhalobenzenes, and fluoro-, (trifluoromethyl)-, and 1,3,5-trifluorobenzene were converted to their corresponding diaryl sulfoxides with FSO3H.SbF5 (1:1) (magic acid)/SO2. Dependency of the yields on the acidity (H0) and the arene structure was demonstrated. Reduction of the formed sulfoxide was also observed as a minor pathway to give diaryl sulfide. The reduction is superacid-catalyzed, and protonated sulfoxides are the key intermediates en route to sulfides. Protonation of several functionalized diaryl sulfoxides was also studied in magic acid/SO2 under stable ion conditions. Unlike the parent diphenyl sulfoxide, which is S-protonated, alkyl-, fluoro-, and trifluoromethyl-substituted diaryl sulfoxides O-protonate to give long-lived sulfoxonium ions. The proposed mechanism for the arene/superacid/SO2 system involves sulfination of the arenium ions, O-protonation of the resulting sulfinic acid, dehydration of the oxonium ion ''ArSO+'' and arylation. In the absence of SO2, the fluorosulfonation, ionization, arylation path becomes dominant. The scope of the reaction is sufficiently broad to be synthetically useful. The methodology is also applicable to unsymmetrical (mixed) diaryl sulfoxides.

  DOI：

  10.1021/jo00005a037

文献信息

• Triazole oxime derivatives having antimycotic acitivity
  申请人：MOCHIDA PHARMACEUTICAL CO., LTD.

  公开号：EP0670315A1

  公开（公告）日：1995-09-06

  Triazole oxime derivatives represented by the formula (I): (where Ar is a phenyl group substituted by 1 or 2 halogen atoms; R¹ and R² are typically such that, when taken together with the adjacent carbon atom, they form a cyclopropylidene group; R³ is a straight-chained, branched or cyclic alkyl group having 1 - 4 carbon atoms; R⁴ is typically an optionally substituted straight-chained or branched alkyl group having 1 - 4 carbon atoms; and the wavy line represents either an E- or Z-type bond) or salts thereof. The triazole derivatives exhibit a marked therapeutic effects not only in in vitro experiments but also in in vivo experiments using laboratory animal models such as Aspergillus infected mice. The derivatives are also safe to use. Therefore, they are extremely useful as therapeutics for various superficial dermatomycoses, deep dermatomycoses and deep mycoses (mycoses in internal organs).

  Triazole oxime 衍生物的化学式（I）表示为： （其中 Ar 是一个被 1 或 2 个卤素原子取代的苯基；R¹ 和 R² 通常是这样的，当与相邻的碳原子一起时，它们形成一个环丙烯基团；R³ 是一个直链、支链或环状的含有 1 - 4 个碳原子的烷基团；R⁴ 通常是一个可选择取代的直链或支链烷基团，含有 1 - 4 个碳原子；波浪线代表 E- 或 Z- 类型键）或其盐。这些三唑衍生物不仅在体外实验中表现出显著的治疗效果，而且在使用实验动物模型（如感染曲霉的小鼠）进行体内实验时也表现出显著的治疗效果。这些衍生物也是安全的。因此，它们在治疗各种浅表真菌病、深部真菌病和深部真菌病（内脏器官真菌病）方面非常有用。
• TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER
  申请人：IDEMITSU KOSAN CO.,LTD.

  公开号：US20210198300A1

  公开（公告）日：2021-07-01

  A transition metal compound from Periodic Table Group 3 to 10 or lanthanide, of formula (I): In formula (I), A 1 and A 2 are independently a crosslinker of formula (II) X is a σ or π-bonding ligand, and plural Xs may differ; Y is a Lewis base, and plural Ys may differ and/or crosslink with Y or X; q is an integer from 1 to 5, representing [(valence of M)−2]; r is an integer from 0 to 3; M is a metal from Group 3 to 10 or a lanthanide; n and m are independently an integer from 0 to 4; and plural Rs may differ. In formula (II), E is C, Si, Ge, or Sn; R 1 and R 2 are independently a H, a halogen, or a C1 to C20 hydrocarbon, optionally halogenated, and may bond together to form a ring, and e is an integer from 1 to 4.

  公式（I）表示来自周期表3到10族或镧系元素的过渡金属化合物：在公式（I）中，A1和A2分别是式（II）的交联剂；X是σ或π配体，且复数个X可能不同；Y是路易斯碱基，复数个Y可能不同且/或与Y或X交联；q是整数1到5，表示[M的价-2]；r是整数0到3；M是来自3到10族或镧系的金属；n和m分别是整数0到4；复数个R可能不同。在公式（II）中，E是C、Si、Ge或Sn；R1和R2分别是H、卤素或C1到C20的烃，可选择卤化，并且可以结合形成环，e是整数1到4。
• Novel onium salt, photopolymerization initiator, energy ray-curing composition containing the initiator, and cured product
  申请人：NIPPON KAYAKU KABUSHIKI KAISHA

  公开号：EP0629613A2

  公开（公告）日：1994-12-21

  The composition of the present invention is excellent in compatibility, transparency and curability and give a cured coat of excellent gloss and of less smell, and cured products of excellent properties can be obtained by curing the composition. The present invention relates to an onium salt represented by the following formula (1): wherein Ar is a mono- to tetra-valent aromatic group, X is a bisphenylsulfonio group which may have a substituent, a is 1-4, b is 0 or 1-3, a + b is 1-4, n is 1-4, and Z is a halide represented by the following formula (3): where M is a boron atom, a phosphorus atom, an arsenic atom or an antimony atom, Q is a halogen atom, m is 3-6, ℓ is 0 or 1, and m + ℓ is 4-6; a photopolymerization initiator containing the onium salt as an active ingredient; an energy ray-curable composition containing the initiator; and a cured product.

  本发明的组合物具有极佳的相容性、透明度和固化性，固化后的涂层光泽度极佳且气味较小，通过固化该组合物可以获得性能优异的固化产品。 本发明涉及一种由下式（1）表示的鎓盐： 其中 Ar 是一价至四价芳香族基团，X 是可具有取代基的双苯磺酰基，a 是 1-4，b 是 0 或 1-3，a + b 是 1-4，n 是 1-4，Z 是由下式（3）表示的卤化物： 其中 M 是硼原子、磷原子、砷原子或锑原子，Q 是卤素原子，m 是 3-6，ℓ 是 0 或 1，m + ℓ 是 4-6；含有作为活性成分的鎓盐的光聚合引发剂；含有该引发剂的能量射线固化组合物；以及固化产品。
• PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME
  申请人：NIPPON KAYAKU KABUSHIKI KAISHA

  公开号：EP0844255A1

  公开（公告）日：1998-05-27

  This invention provides an energy ray curable composition which has excellent curability. The composition contains a cationic polymerizable substance, a photopolymerization initiator comprised of a specified onium salt and a pigment as occasion demands. The curable composition is excellent in curability, and cured paint films obtained therefrom shows excellent glossiness. This composition can be blended in white inks, printing inks, paints, resist inks, wood fillers and the like.

  本发明提供了一种能量射线固化组合物，它具有优异的固化性能。该组合物含有一种阳离子可聚合物质、一种由特定鎓盐组成的光聚合引发剂和一种颜料。该固化组合物具有极佳的固化性，由此获得的固化漆膜具有极佳的光泽度。这种组合物可用于调配白墨、印刷油墨、涂料、抗蚀剂油墨、木材填料等。
• INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME
  申请人：China Petroleum & Chemical Corporation

  公开号：EP2481760A1

  公开（公告）日：2012-08-01

  The present invention discloses an initiating system for cationic polymerization and a polymerization process. The present application relates to an initiating system for cationic polymerization of cationic-polymerizable monomers, and a process for cationic polymerization of cationic-polymerizable monomers by using the initiating system. The present invention particular involves an initiating system for cationic polymerization of cationic-polymerizable monomers in an aqueous reaction medium, and a process for cationic polymerization of cationic-polymerizable monomers by using the initiating system in an aqueous reaction medium.

  本发明公开了一种阳离子聚合引发体系和一种聚合工艺。本申请涉及一种用于阳离子可聚合单体阳离子聚合的引发体系，以及使用该引发体系进行阳离子可聚合单体阳离子聚合的工艺。本发明尤其涉及一种在水性反应介质中使可阳离子聚合的单体进行阳离子聚合的引发体系，以及在水性反应介质中使用该引发体系使可阳离子聚合的单体进行阳离子聚合的工艺。