THE TRICHLOROPHENOLS ... CAN PRODUCE REDNESS & EDEMA ON SKIN CONTACT ... . IN THE EYE THEY ... SOMETIMES /CAUSED/ CORNEAL INJURY & IRITIS. ... SYSTEMIC EFFECTS ARE NOT DESCRIBED BUT PRESUMABLY RESEMBLE THOSE OF PHENOL POISONING. /TRICHLOROPHENOLS/
SYMPTOMATOLOGY: 1. Burning pain in mouth and throat. White necrotic lesions in mouth, esophagus and stomach. Abdominal pain, vomiting ... and bloody diarrhea. 2. Pallar, sweating weakness, headache, dizziness, tinnitus. 3. Shock: Weak irregular pulse, hypotension, shallow respirations, cyanosis, pallor, and a profound fall in body temperature. 4. Possibly fleeting excitement and confusion, followed by unconsciousness ... . 5. Stentorous breathing, mucous rales, rhonchi, frothing at nose and mouth and other signs of pulmonary edema are sometimes seen. Characteristic odor of phenol on the breath. 6. Scanty, dark-colored ... urine ... moderately severe renal insufficiency may appear. 7. Methemoglobinemia, Heinz body hemolytic anemia and hyperbilirubinemia have been reported ... 8. Death from respiratory, circulatory or cardiac failure. 9. If spilled on skin, pain is followed promptly by numbness. The skin becomes blanched, and a dry opaque eschar forms over the burn. When the eschar sloughs off, a brown stain remains. /Phenol/
Symptoms and pulmonary function were evaluated in 7 subjects exposed to trichlorophenol. Symptoms from upper airways and chest were more common among exposed than in control subjects (60% and 10%). Significantly reduced forced expiratory flow at 75% of vital capacity and incr closing vol were measured, while other spirometric variables and the transfer factor of the lung for carbon monoxide were normal. Incr elastic recoil pressure of the lung and x-ray signs of lung tissue involvement were noticed in 2 subjects. The findings suggest an irritating effect on the lung of trichlorophenol, and it cannot be excluded that long term exposure may produce pulmonary fibrosis. /Trichlorophenol/
... THE SODIUM SALT (DOWICIDE B) IS MORE TOXIC BY MOUTH & MORE IRRITATING ON THE SKIN THAN THE 2 FREE PHENOLS /2,4,5- & 2,4,6-TRICHLOROPHENOL/. ALL ARE LESS TOXIC THAN SIMPLE PHENOL.
Adverse health effects have been seen in workers exposed to chlorophenols contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin or to products synthesized from trichlorophenol. These effects, probably due to 2,3,7,8-tetrachlorodibenzo-p-dioxin, include persistent chloracne, liver dysfunction, neuromuscular weakness, porphyria and psychological changes. /Trichlorophenols/
THEY APPEAR NOT TO PENETRATE INTACT RABBIT OR GUINEA PIG SKIN (PERCUTANEOUS ABSORPTION) IN SIGNIFICANT AMOUNTS, IN CONTRAST TO PHENOL & ITS TETRA- & PENTA-CHLORO DERIVATIVES ... . /TRICHLOROPHENOLS/
来源:Hazardous Substances Data Bank (HSDB)
吸收、分配和排泄
化合物从胃肠道和注射部位被吸收。/氯酚/
The compounds are absorbed from the gastroenteric tract and from parenteral sites of injection. /Chlorophenols/
Anion variation on a cobalt(iii) complex of salen-type ligand tethered by four quaternary ammonium salts for CO2/epoxide copolymerization
作者：Jina Yoo、Sung Jae Na、Hyeong Cheol Park、Anish Cyriac、Bun Yeoul Lee
DOI：10.1039/b920992a
日期：——
scrambling two X's in 6, 10, or 12 are replaced with the corresponding [X⋯H⋯X]− homoconjugate. These complexes, which adopt an unusual imine uncoordinated structure, are excellent catalysts for CO2/propylene oxide copolymerization (turnover frequency (TOF), 8300–16 000 h−1). In all cases, the complex containing the homoconjugate [X⋯H⋯X]− shows higher activity than the corresponding phenol-free complex.
BF的阴离子交换4 -发生通过搅拌钴（III） 的复合体 Salen四元系链的三型配体 铵盐BF 4 -过的淤浆的盐钠CH 2 Cl 2中的化合物，得到一个含四个X的络合物钴 （X = 2,4,5-三氯酚盐，6 ; X =4-硝基酚盐，10 ; X =2,4-二氯苯酚盐，12）。的1 H和13 C NMR光谱与一个不寻常的亚胺不协调结构一致。他们俩Salen-苯氧基和两个X持续与 钴（III） 形成方形平面 钴酸盐复杂，而另外两个X通过协调和解配向方形平面的轴向位置争夺。复数的另一种形式（X =2,4,5-三氯酚盐，14 ; X =4-硝基酚盐，15 ; X =2,4-二氯苯酚盐，16）也被制备，其中，所述加扰两个X在6，10，或12与相应的[X取代⋯H[X] -同缀物。这些络合物采用不常见的亚胺不协调结构，是CO 2 /的极佳催化剂。环氧丙烷共聚（周转频率（TOF），8300-16 000
Hypervalent Iodine/Triflate Hybrid Benzdiyne Equivalents: Access to Controlled Synthesis of Polycyclic Aromatic Compounds
作者：Tsugio Kitamura、Keisuke Gondo、Juzo Oyamada
DOI：10.1021/jacs.7b04483
日期：2017.6.28
6-trichlorophenoxide. The 1,3-benzdiyne equivalent also underwent the chemoselective stepwise generation of arynes and the double cycloaddition with different arynophiles. These hybrid benzdiyne equivalents provided the double cycloadducts in high yields and enabled the convenient one-pot procedure for synthesis of polycyclic aromatic compounds.
The present invention related to a method of manufacturing a polycarbonate including the process of copolymerizing epoxide compound and CO2 using cobalt(III) or chromium(III), where the ligands contains at least 3 ammonium cations, central metal has formal −1 charge, and conjugated anions of the two cationic ammonium groups are acid-base homoconjugation, as catalyst.
According to the present invention, the initial induction time can be reduced when the said polycarbonate is manufactured and it is possible to improve the activity of the catalyst and the molecular weight of the obtained polymer.
The present invention relates to a method of manufacturing a polycarbonate including the process of copolymerizing epoxide compound and CO2 using cobalt(III) or chromium(III), where the ligands contains at least 3 ammonium cations, central metal has formal −1 charge, and conjugated anions of the two cationic ammonium groups are acid-base homoconjugation, as catalyst. According to the present invention, the initial induction time can be reduced when the polycarbonate is manufactured and it is possible to improve the activity of the catalyst and the molecular weight of the obtained polymer.
Composition for inhibiting the growth of microorganisms in metal working fluid and method for inhibiting the growth of microorganisms in such fluids
申请人：Merck & Co., Inc.
公开号：EP0004610A2
公开（公告）日：1979-10-17
Compositions of 1,3,5-tris-(furfuryl)hexahydro-s-triazine are useful as antimicrobial agents particularly when added to metal-working compositions subject to fungal and bacterial attack.
