Bis-(4-nitrophenyl)cyanomethane | 56577-69-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Bis-(4-nitrophenyl)cyanomethane
• 英文别名: Bis(4-nitrophenyl)cyanomethane；Bis(4-nitrophenyl)-acetonitril；2,2-Bis(4-nitrophenyl)acetonitrile
• CAS: 56577-69-6
• 化学式: C₁₄H₉N₃O₄
• 分子量: 283.243
• InChiKey: HLUVMXKNPIBAJK-UHFFFAOYSA-N

物化性质

• 沸点：
  487.3±45.0 °C(Predicted)
• 密度：
  1.394±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  115
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Bis-(4-nitrophenyl)cyanomethane 、 四甲基胍 以 乙腈 为溶剂， 生成
  参考文献：
  名称：

  Hojatti, Mahmood; Leffek, Kenneth T., Canadian Journal of Chemistry, 1984, vol. 62, p. 2653 - 2656

  摘要：

  DOI：
• 作为产物：
  描述：

  二苯乙腈 在 硝酸 作用下， 生成 Bis-(4-nitrophenyl)cyanomethane
  参考文献：
  名称：

  Pruszynski, Przemyslaw; Leffek, Kenneth T., Canadian Journal of Chemistry, 1991, vol. 69, # 2, p. 205 - 210

  摘要：

  DOI：

文献信息

• Method and composition for the assay of albumin
  申请人：MILES INC.

  公开号：EP0414935A1

  公开（公告）日：1991-03-06

  A method and composition for the assay for albumin at an essentially neutral to an alka­line pH. The method utilizes indicator dyes that, when sufficiently buffered in a pH range of approximately 6 to approximately 8, allows the detection of albumin in urine or serum. The indicator dyes utilized in the method of the present invention have the general formula: wherein R₁ and R₂ are substituted aromatic hetero­cyclic or carbocyclic moieties having one or more electron-withdrawing functionalities present on the aromatic ring; R₃ is a substituted aromatic heterocyclic or carbocyclic moiety having one or more electron-withdrawing functionalities present on the aromatic ring, or R₃ is a non-aromatic electron-withdrawing moiety; R₄ is a substituted quasi-aromatic quinone-like heterocyclic or carbo­cyclic moiety having one or more electron-with­drawing functionalities present on the quasi-­aromatic quinone-like ring; and R₅ is a substi­tuted aromatic heterocyclic or carbocyclic moiety having one or more electron-withdrawing function­alities, including at least one hydroxy function­ality, present on the aromatic ring.

  一种在基本中性至碱性 pH 值条件下检测白蛋白的方法和组合物。该方法利用指示剂染料，在 pH 值约为 6 至 8 的范围内充分缓冲后，可检测尿液或血清中的白蛋白。本发明方法中使用的指示剂染料具有通式： 其中，R₁ 和 R₂ 是取代的芳香杂环或碳环分子，在芳香环上具有一个或多个抽电子官能团；R₃ 是取代的芳香杂环或碳环分子，在芳香环上具有一个或多个抽电子官能团；或者 R₃ 是非芳香族抽电子分子；R₄ 是取代的类芳香醌杂环或碳环分子，在类芳香醌环上具有一个或 多个抽电子官能团；以及 R₅ 是取代的芳香杂环或碳环分子，在芳香环上具有一个或 多个抽电子官能团，包括至少一个羟基官能团。
• Kinetic study of the reactions of various types of C-acids with amine bases in acetonitrile. An unusual effect of common BH<sup>+</sup> cation on the rate constants
  作者：Wlodzimierz Galezowski、Iwona Grzeskowiak、Arnold Jarczewski

  DOI：10.1139/cjc-77-5-6-1042

  日期：——

  The rates of proton transfer reactions between C-acids of different types such as 1-(4-nitrophenyl)-1-nitroalkanes, 4-nitrophenylcyanomethanes, and 2,4,6-trinitrotoluene, and organic bases such as 1,1,3,3-tetrametylguanidine, 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD), and tri-n-butylamine have been measured in acetonitrile at pseudo-first-order conditions. A general equation for the rates of proton transfer reactions between C-acids and bases with product existing in two forms, ions and ion pairs, has been derived and its applicability tested. The equation works well except for reactions of 1-(4-nitrophenyl)-1-nitroalkanes with guanidines for which the second-order rate constant is diminished with concentration of guanidinium cation, while tetrabutylammonium salts accelerate the reactions. Possible reasons for this are discussed.
• Effect of cationic micelles on the acidity of carbon acids and phenols. Electronic and proton nuclear magnetic resonance spectral studies of nitro carbanions in micelles
  作者：M. J. Minch、M. Giaccio、R. Wolff

  DOI：10.1021/ja00846a035

  日期：1975.6
• IMMUNOASSAY METHOD
  申请人：INTERNATIONAL MUREX TECHNOLOGIES CORPORATION

  公开号：EP0643832A1

  公开（公告）日：1995-03-22
• US5194390A
  申请人：——

  公开号：US5194390A

  公开（公告）日：1993-03-16