(4-methoxyphenyl)diphenyl-arsane | 24579-39-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (4-methoxyphenyl)diphenyl-arsane
• 英文别名: 4-(diphenylarsino)anisole；p-anisyldiphenylarsine；<4-Methoxy-phenyl>-diphenyl-arsin；Diphenyl-(4-methoxy-phenyl)-arsin；(4-Methoxy-phenyl)-diphenyl-arsin；(4-Methoxyphenyl)-diphenylarsane
• CAS: 24579-39-3
• 化学式: C₁₉H₁₇AsO
• 分子量: 336.265
• InChiKey: BHMQOVRSEDEUFD-UHFFFAOYSA-N

物化性质

• 熔点：
  120.0-121.5 °C
• 沸点：
  254-255 °C(Press: 20 Torr)

计算性质

• 辛醇/水分配系数(LogP)：
  2.21
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-溴苯甲醚 以60%的产率得到
  参考文献：
  名称：

  ROSSI R. A.; ALONSO R. A.; PALACIOS S. M., J. ORG. CHEM., 1981, 46, NO 12, 2498-2502

  摘要：

  DOI：

文献信息

• Catalytic Solvent-Free Arsination:  First Catalytic Application of Pd−Ar/As−Ph Exchange in the Syntheses of Functionalized Aryl Arsines
  作者：Fuk Yee Kwong、Chi Wai Lai、Kin Shing Chan

  DOI：10.1021/ja005875s

  日期：2001.9.1
• Formation and reactions of diorganophosphinite ions in liquid ammonia. Synthesis of triorganophosphine oxides by the SRN1 mechanism
  作者：Esteban R. N. Bornancini、Roberto A. Rossi

  DOI：10.1021/jo00295a019

  日期：1990.4
• One-Pot Palladium-Catalyzed Cross-Coupling Reaction of Aryl Iodides with Stannylarsanes and Stannylstibanes
  作者：Mariana Bonaterra、Sandra E. Martín、Roberto A. Rossi

  DOI：10.1021/ol0349357

  日期：2003.7.1

  The reaction of Ph3As and Ph3Sb with Na metal in liquid ammonia gives Ph2M- ions (M = As, Sb) that react with n-Bu3SnCl to afford n-Bu3Sn-MPh2 (1). The ammonia was allowed to evaporate, and toluene was added. The Pd-catalyzed cross-coupling reactions of these stannanes with aryl iodides afford functionalized triaryl-arsanes and triaryl-stibanes in high yields in a one-pot procedure (80-99%). The use of the commercially available, air-stable, and inexpensive Ph3M as the initial reagent and the one-pot process make this method a useful approach. This is the first report on the synthesis of 1 and the exploration of its chemistry.