[EN] SMALL MOLECULE INHIBITORS OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE [FR] INHIBITEURS À PETITES MOLÉCULES DE DIHYDROOROTATE DÉSHYDROGÉNASE DE PLASMODIUM FALCIPARUM
SMALL MOLECULE INHIBITORS OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE
申请人:Bastos Cecilia
公开号:US20110130381A1
公开(公告)日:2011-06-02
Inhibitors of dihydroorotate dehydrogenase (DHODH) for the
Plasmodium
enzyme have been identified and characterized. The inhibitors have high specificity, submicromolar efficacy against cultured parasite strains, exhibit drug-like properties, and are not overtly cytotoxic.
[EN] SMALL MOLECULE INHIBITORS OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE<br/>[FR] INHIBITEURS À PETITES MOLÉCULES DE DIHYDROOROTATE DÉSHYDROGÉNASE DE PLASMODIUM FALCIPARUM