二氯硝基乙酸乙酯 | 24482-75-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 二氯硝基乙酸乙酯
• 英文名称: ethyl dichloronitroacetate
• 英文别名: Ethyl 2,2-Dichloro-2-nitroacetate
• CAS: 24482-75-5
• 化学式: C₄H₅Cl₂NO₄
• 分子量: 201.994
• InChiKey: BQNLRKAHUIBXDJ-UHFFFAOYSA-N

物化性质

• 沸点：
  72 °C(Press: 8 Torr)
• 密度：
  1.511±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  72.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  二氯硝基乙酸乙酯 在 盐酸 作用下， 反应 19.0h， 以15%的产率得到二氯硝基甲烷
  参考文献：
  名称：

  Synthesis of chloro- and dichloronitromethanes

  摘要：

  DOI：

  10.1007/bf00954250
• 作为产物：
  描述：

  (Z)-2-Chloro-1-ethoxy-2-nitro-ethenol; compound with ammonia 在 磺酰氯 作用下， 以 乙醚 为溶剂， 反应 0.25h， 以81%的产率得到二氯硝基乙酸乙酯
  参考文献：
  名称：

  Methods of preparation of halonitroacetic acid derivatives and study of the fungicidal activity of their amides and anilides on Sclerotinia sclerotiorum

  摘要：

  Anilides (II)-(XIII), (XV), (XVI), (XIX), and chloronitroacetamide (XVIII) were obtained in a yield of 38-90% by ammonolysis of the corresponding dichloro- (I) and chloronitroacetyl chlorides (XIV). Dichloronitroacetanilides (II), (V), ethyl (XX), propyl (XXI) esters and amide of dichloronitroacetic acid (XXII) were obtained by chlorination of anhydrous ammonium and sodium salts by sulfuryl chloride in absolute ether. Bromination of anhydrous salts of bromo- and chloronitroacetic acids proceeds readily in absolute alcohol. The yields of the bromination [(XXIII)-(XXVIII)] and chlorination products were 49-99%. Results are given of tests of some of the amides and anilides obtained for the inhibition of growth and development of the Sclerotinia sclerotiorum fungus.

  DOI：

  10.1007/bf00958561

文献信息

• Martynov, I. V.; Postnova, L. V.; Bikkineev, R. Kh., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, # 8, p. 1571 - 1573
  作者：Martynov, I. V.、Postnova, L. V.、Bikkineev, R. Kh.、Yurtanov, A. I.

  DOI：——

  日期：——
• Macbeth; Traill, Journal of the Chemical Society, 1925, vol. 127, p. 896
  作者：Macbeth、Traill

  DOI：——

  日期：——
• Dichloronitroacetic acid derivatives as acylating agents for primary amines, ammonia, and phenylhydrazine
  作者：A. I. Yurtanov、Z. M. Adkhamova、S. K. Baidildaeva

  DOI：10.1007/bf00864535

  日期：1992.5

  The corresponding carbamic acid derivatives were obtained (28-91% yields) as a result of the reaction of dichloronitroacetic acid derivatives, O2NCCl2COR, (1a-c, R = OEt, OCH2Ph, NH2) with ammonia, methylamine, benzylamine, glycine, phenylhydrazine, and aniline. The probable mechanism of the process and factors that affect the nature of the departing group were discussed.
• YURTANOV, A. I.;ANUFRIEV, V. I.;KULISH, E. V.;MIXAJLYUCHENKO, I. G.;SHULY+, IZV. AN CCCP. CEP. XIM.,(1991) N, S. 823-830
  作者：YURTANOV, A. I.、ANUFRIEV, V. I.、KULISH, E. V.、MIXAJLYUCHENKO, I. G.、SHULY+

  DOI：——

  日期：——
• MARTYNOV, I. V.;BIKKINEV, R. X.;UVAROV, V. I., IZV. AN CCCP. CEP. XIM., 1986, N 4, 941-942
  作者：MARTYNOV, I. V.、BIKKINEV, R. X.、UVAROV, V. I.

  DOI：——

  日期：——