linseed oil | 857213-89-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: linseed oil
• 英文别名: TG(18:1/18:2/18:3)；(2-Octadeca-9,12-dienoyloxy-3-octadeca-9,12,15-trienoyloxypropyl) octadec-9-enoate；(2-octadeca-9,12-dienoyloxy-3-octadeca-9,12,15-trienoyloxypropyl) octadec-9-enoate
• CAS: 857213-89-9
• 化学式: C₅₇H₉₈O₆
• 分子量: 879.402
• InChiKey: OTUIORVXGJUHBH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  20.3
• 重原子数：
  63
• 可旋转键数：
  50
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  linseed oil 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 6.0h， 生成 9,12,15-octadecatrien-1-ol 、 9,12-octadecadien-1-ol 、 油醇
  参考文献：
  名称：

  Synthesis of pH-sensitive micelles from linseed oil using atom transfer radical polymerisation (ATRP)

  摘要：

  This paper reports the synthesis of an amphiphilic copolymer from linseed oils and its successive auto-association in water into pH-sensitive micelles. An original ATRP lipoinitiator is first designed from linseed oil in two steps. tert-butyl acrylate (tBA) polymerization is consequently initiated from this original initiator and amphiphilic copolymers are obtained after subsequent acidolysis of the PtBA block into poly(acrylic acid) (PAA). The ability of a lipid-b-PAA copolymer to auto-associate in water is finally investigated through different techniques (Fluorescence, Surface Tension, QELS). This copolymer forms well-defined micelles in acidic media with a low critical micellar concentration (cmc) of 7.6 mg L-1 and dissociates when the pH is raised above 7. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2012.07.041

文献信息

• Synthesis of pH-sensitive micelles from linseed oil using atom transfer radical polymerisation (ATRP)
  作者：Louise Hespel、Elise Kaifas、Laurence Lecamp、Luc Picton、Gaëlle Morandi、Fabrice Burel

  DOI：10.1016/j.polymer.2012.07.041

  日期：2012.9

  This paper reports the synthesis of an amphiphilic copolymer from linseed oils and its successive auto-association in water into pH-sensitive micelles. An original ATRP lipoinitiator is first designed from linseed oil in two steps. tert-butyl acrylate (tBA) polymerization is consequently initiated from this original initiator and amphiphilic copolymers are obtained after subsequent acidolysis of the PtBA block into poly(acrylic acid) (PAA). The ability of a lipid-b-PAA copolymer to auto-associate in water is finally investigated through different techniques (Fluorescence, Surface Tension, QELS). This copolymer forms well-defined micelles in acidic media with a low critical micellar concentration (cmc) of 7.6 mg L-1 and dissociates when the pH is raised above 7. (C) 2012 Elsevier Ltd. All rights reserved.