Direct synthesis of imines by 9-azabicyclo-[3,3,1]nonan-N-oxyl/KOH-catalyzed aerobic oxidative coupling of alcohols and amines
作者:Yan Wan、Jia-Qi Ma、Chao Hong、Mei-Chao Li、Li-Qun Jin、Xin-Quan Hu、Bao-Xiang Hu、Wei-Min Mo、Nan Sun、Zhen-Lu Shen
DOI:10.1016/j.cclet.2017.10.006
日期:2018.8
Abstract A simple and efficient method for preparation of imines by the oxidative coupling of benzyl alcohols with aromatic amines or aliphatic amines was developed. The reaction was catalyzed by 9-azabicyclo[3.3.1]nonan-N-oxyl (ABNO)/KOH with air as the economic and green oxidant. Under the optimal reaction conditions, a variety of imines were obtained in 80%-96% isolated yields.
摘要提出了一种简单有效的方法,通过苯甲醇与芳族胺或脂肪族胺的氧化偶合来制备亚胺。该反应由9-氮杂双环[3.3.1]壬南-N-氧基(ABNO)/ KOH催化,空气为绿色经济氧化剂。在最佳反应条件下,以80%-96%的分离产率获得了各种亚胺。