Thiobenzoesaeure-S-<2-amino-ethylester> | 46053-57-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Thiobenzoesaeure-S-<2-amino-ethylester>
• 英文别名: S-<2-Amino-ethyl>-thiobenzoat；S-Benzoyl-cysteamin；Thiobenzoesaeure-S-(2-amino-ethylester)；S-Benzoylcysteamine；S-(2-aminoethyl) benzenecarbothioate
• CAS: 46053-57-0
• 化学式: C₉H₁₁NOS
• 分子量: 181.258
• InChiKey: RXAXEXYDIIGAFS-UHFFFAOYSA-N

物化性质

• 沸点：
  282.3±32.0 °C(Predicted)
• 密度：
  1.168±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  68.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  硫代苯甲酸 、 2-溴乙胺氢溴酸盐 生成 Thiobenzoesaeure-S-<2-amino-ethylester>
  参考文献：
  名称：

  Some S-Substituted Derivatives of 2-Aminoethanethiol²

  摘要：

  DOI：

  10.1021/jo01068a037

文献信息

• Antiradiation Compounds I
  作者：William O. Foye、Ronald N. Duvall、James Mickles

  DOI：10.1002/jps.2600510219

  日期：1962.2

  attempt to provide compounds having protective effects in animal cells against ionizing radiation and which are less toxic than MEA itself. In general, toxicity to animals was reduced and good protective ability against X-radiation was retained in some of the esters. The dithiocarbamic acid of MEA was also prepared, but attempts to acylate this compound, which showed good antiradiation effects in close

  已经制备了一系列β-巯基乙胺（MEA）的S-酰基衍生物，以试图提供在动物细胞中具有防止电离辐射的保护作用并且比MEA本身毒性小的化合物。通常，在某些酯类中，对动物的毒性降低，并且对X射线具有良好的防护能力。还制备了MEA的二硫代氨基甲酸，但是尝试酰化该化合物，该化合物在接近小鼠毒性剂量水平时显示出良好的抗辐射作用，产生了多种分解产物。
• PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOSITION
  申请人：FUJIFILM Corporation

  公开号：US20180108492A1

  公开（公告）日：2018-04-19

  Provided are a photoelectric conversion element, a solar cell using the photoelectric conversion element, and a composition. The photoelectric conversion element includes a first electrode including a photosensitive layer, which includes a light absorbing agent, on a conductive support. The light absorbing agent includes a compound having a perovskite-type crystal structure that includes organic cations represented by the following Formulae (1) and (2), a cation of a metal atom, and an anion. R 1 —N(R 1a ) 3 + Formula (1) R 2 —N(R 2a ) 3 + Formula (2) In Formulae (1) and (2), R 1 represents a specific group such as an alkyl group (including a specific substituent group in a case where the number of carbons is 1 or 2), and a cycloalkyl group. R 2 represents a methyl group, an ethyl group, and the like. R 1a and R 2a represent a specific group such as a hydrogen atom and an alkyl group.

  提供了一个光电转换元件、使用该光电转换元件的太阳能电池以及一种组合物。该光电转换元件包括第一电极，该第一电极包括一个光敏层，该光敏层包括一个吸光剂，该吸光剂包括具有钙钛矿型晶体结构的化合物，其中该晶体结构包括以下式(1)和(2)所表示的有机阳离子、金属原子的阳离子和阴离子。在式(1)和(2)中，R1代表一个特定基团，如烷基基团(在碳数为1或2时包括一个特定的取代基团)和环烷基基团。R2代表甲基基团、乙基基团等。R1a和R2a代表氢原子和烷基基团等特定基团。
• [EN] SUBSTITUTED AMINO-THIOL AND AMINO-DISULFIDE COMPOUNDS, AND USES THEREOF<br/>[FR] COMPOSÉS DE TYPE AMINO-THYOL ET AMINO-DISULFIDE SUBSTITUÉS ET LEURS UTILISATIONS
  申请人：THE REGENTS OF THE UNIV OFCALIFORNIA

  公开号：WO2020198529A1

  公开（公告）日：2020-10-01

  The disclosure provides for new substituted cysteamine and cystamine compounds, pharmaceutical compositions made thereof, and methods thereof including the treatment of any disease or disorder in a subject that can benefit from one or more of the bioprotective effects of the compounds, including but not limited to, binding of cystine, reducing oxidative stress, increasing adiponectin levels and/or increasing brain-derived neurotrophic factors. Examples of such disease and disorders, include but are not limited to, cystinosis, and fatty liver diseases.

  该披露提供了新的替代半胱氨酸和半胱醇化合物，制备其制药组合物以及包括治疗受益于该化合物的生物保护作用之一或多个的任何疾病或障碍的方法，包括但不限于，结合胱氨酸，减少氧化应激，增加脂联素水平和/或增加脑源性神经营养因子。这些疾病和障碍的例子包括但不限于囊性病和脂肪肝病。
• Acyl group carriers
  作者：V. M. Kopelevich、G. S. Evdokimova、A. F. Ryazantseva、E. S. Zhdanovich

  DOI：10.1007/bf00760193

  日期：1970.11
• MUNSON, H. R. ,, JR
  作者：MUNSON, H. R. ,, JR

  DOI：——

  日期：——