2-chloroethyl p-toluenesulfinate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-chloroethyl p-toluenesulfinate
• 英文别名: 2-Chloroethyl 4-methylbenzenesulfinate
• 化学式: C₉H₁₁ClO₂S
• 分子量: 218.704
• InChiKey: OSGHTHKORBZDAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  45.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对甲苯亚磺酸 在 氯化亚砜 、 silica gel 作用下， 反应 0.69h， 生成 2-chloroethyl p-toluenesulfinate
  参考文献：
  名称：

  ONE-POT AND SIMPLE REACTION FOR THE SYNTHESIS OF ALKYL p-TOLUENESULFINATE ESTERS UNDER SOLID-PHASE CONDITIONS

  摘要：

  A manipulatively one-pot and rapid method for the synthesis of alkyl p-toluenesulfinate esters 1 from p-toluenesulfinic acid, supported thionyl chloride on silica gel and aliphatic alcohols in solid phase conditions is described.

  DOI：

  10.1080/10426500008043672

文献信息

• Organic Reactions under Solid-State Conditions
  作者：Abdol R. Hajipour、Shadpour E. Mallakpour

  DOI：10.1080/10587250108023716

  日期：2001.2.1

  Manipulatively simple and rapid methods are described for the synthesis of: chiral sulfinate esters from sulfonyl chlorides and sufonic acids; aldehydes and ketones from oximes, alcohols, hydrozones; sulfoxides from sulfides; and disulfides from thiols. The chemical yields are good to excellent and diastereoselectivity is high.
• An efficient and novel method for the synthesis of sulfinate esters under solvent-free conditions
  作者：Abdol R. Hajipour、Ali R. Falahati、Arnold E. Ruoho

  DOI：10.1016/j.tetlet.2006.02.080

  日期：2006.4

  The present letter describes a reliable one-stage process for the preparation of sulfinate esters from the corresponding sulfinic acid and alcohols in the presence of N,N'-dicyclohexylcarbodiimide (DCC) under solvent-free conditions. (c) 2006 Elsevier Ltd. All rights reserved.
• ONE-POT AND SIMPLE REACTION FOR THE SYNTHESIS OF ALKYL <i>p</i>-TOLUENESULFINATE ESTERS UNDER SOLID-PHASE CONDITIONS
  作者：A. M. Hajipour、S. E. Mallakpour、A. Afrousheh

  DOI：10.1080/10426500008043672

  日期：2000.5.1

  A manipulatively one-pot and rapid method for the synthesis of alkyl p-toluenesulfinate esters 1 from p-toluenesulfinic acid, supported thionyl chloride on silica gel and aliphatic alcohols in solid phase conditions is described.