(3,4-Diacetoxy-phenyl)-acetic acid methyl ester | 35400-16-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: (3,4-Diacetoxy-phenyl)-acetic acid methyl ester
• 英文别名: Methyl 3,4-diacetoxyphenylacetate；methyl 2-(3,4-diacetyloxyphenyl)acetate
• CAS: 35400-16-9
• 化学式: C₁₃H₁₄O₆
• 分子量: 266.251
• InChiKey: AUDYUOBTVAKTHH-UHFFFAOYSA-N

物化性质

• 沸点：
  347.7±37.0 °C(Predicted)
• 密度：
  1.224±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (3,4-Diacetoxy-phenyl)-acetic acid methyl ester 在 lithium aluminium tetrahydride 作用下， 生成 羟基酪醇
  参考文献：
  名称：

  Antioxidative activities of Olea europaea leaves and related phenolic compounds

  摘要：

  Olea europaea leaves, oleuropein, hydroxytyrosol and tyrosol were compared with vitamin E and BHT, with regard to their antioxidative activities, by kinetic studies in model systems. The thermal initiated oxidation of methyl linoleate was performed in homogeneous solution at 60-degrees or 40-degrees with or without antioxidants. Olea europaea extracts, oleuropein and hydroxytyrosol were much more effective than BHT or vitamin E in extending the induction period. Assuming a stoichiometric factor f = 2 for BHT, this coefficient of inhibition reached 5 for hydroxytyrosol, 7 for oleuropein and 10 for O. europaea extracts. These extracts owe their antioxidative properties to their high oleuropein content (19% w/w) and also to a lesser amount of flavonoids (1.8% w/w with 0.8% of luteolin 7-glucoside). Tyrosol showed neither antioxidant nor prooxidant activity. No synergistic effect on the preservation of methyl linoleate was found when vitamin E was used together with tyrosol or O. europaea extracts.

  DOI：

  10.1016/0031-9422(92)80255-d
• 作为产物：
  描述：

  3,4-二羟基苯乙酸 生成 (3,4-Diacetoxy-phenyl)-acetic acid methyl ester
  参考文献：
  名称：

  Antioxidative activities of Olea europaea leaves and related phenolic compounds

  摘要：

  Olea europaea leaves, oleuropein, hydroxytyrosol and tyrosol were compared with vitamin E and BHT, with regard to their antioxidative activities, by kinetic studies in model systems. The thermal initiated oxidation of methyl linoleate was performed in homogeneous solution at 60-degrees or 40-degrees with or without antioxidants. Olea europaea extracts, oleuropein and hydroxytyrosol were much more effective than BHT or vitamin E in extending the induction period. Assuming a stoichiometric factor f = 2 for BHT, this coefficient of inhibition reached 5 for hydroxytyrosol, 7 for oleuropein and 10 for O. europaea extracts. These extracts owe their antioxidative properties to their high oleuropein content (19% w/w) and also to a lesser amount of flavonoids (1.8% w/w with 0.8% of luteolin 7-glucoside). Tyrosol showed neither antioxidant nor prooxidant activity. No synergistic effect on the preservation of methyl linoleate was found when vitamin E was used together with tyrosol or O. europaea extracts.

  DOI：

  10.1016/0031-9422(92)80255-d