4-dibenzylaminophenyl 4-methoxyphenyl ether

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-dibenzylaminophenyl 4-methoxyphenyl ether
• 英文别名: N,N-dibenzyl-4-(4-methoxyphenoxy)aniline
• 化学式: C₂₇H₂₅NO₂
• 分子量: 395.501
• InChiKey: CFWNWRANWLRFMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N,N-联苄基-4-溴苯胺 在 正丁基锂 、 naphthalene-1,8-diylbis(diphenylmethylium) diperchlorate 作用下， 以 四氢呋喃 、 正己烷 、 二氯甲烷 为溶剂， 反应 4.0h， 生成 4-dibenzylaminophenyl 4-methoxyphenyl ether
  参考文献：
  名称：

  Bis(triarylmethylium)-Mediated Diaryl Ether Synthesis:  Oxidative Arylation of Phenols with N,N-Dialkyl-4-phenylthioanilines

  摘要：

  Various aryl 4-dialkylaminophenyl ethers were readily synthesized without heating in good yield from phenols and N,N-dialkyl-4-phenylthioanilines. This oxidative arylation of phenols was successfully promoted by a bis(diphenylmethylium)naphthalenediyl dication via ipso-substitution of the phenylthio group in the anilines through a radical process.

  DOI：

  10.1021/ja051839n

文献信息

• Bis(triarylmethylium)-Mediated Diaryl Ether Synthesis:  Oxidative Arylation of Phenols with <i>N</i>,<i>N</i>-Dialkyl-4-phenylthioanilines
  作者：Terunobu Saitoh、Junji Ichikawa

  DOI：10.1021/ja051839n

  日期：2005.7.13

  Various aryl 4-dialkylaminophenyl ethers were readily synthesized without heating in good yield from phenols and N,N-dialkyl-4-phenylthioanilines. This oxidative arylation of phenols was successfully promoted by a bis(diphenylmethylium)naphthalenediyl dication via ipso-substitution of the phenylthio group in the anilines through a radical process.