N-hydroxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide | 323180-93-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-hydroxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide
• 英文别名: 4-trifluoromethylnicotinic acid-N-methyl-N-hydroxy-amide
• CAS: 323180-93-4
• 化学式: C₈H₇F₃N₂O₂
• 分子量: 220.151
• InChiKey: YTWXKRNHFVDPSG-UHFFFAOYSA-N

物化性质

• 沸点：
  333.5±52.0 °C(Predicted)
• 密度：
  1.444±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  53.4
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N-hydroxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide 、 氯化异氰盐酸盐 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 生成 [methyl-[4-(trifluoromethyl)pyridine-3-carbonyl]amino]pyridine-4-carboxylate
  参考文献：
  名称：

  [EN] TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES
  [FR] TRIFLUOROMÉTHYLPYRIDINE CARBOXAMIDES COMME PESTICIDES

  摘要：

  化合物的结构式 I（I），其中取代基如权利要求1所定义的那样，可用作杀虫剂。

  公开号：

  WO2014023531A1
• 作为产物：
  描述：

  4-三氟甲基烟酸 在 氯化亚砜 、 三乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 5.0h， 生成 N-hydroxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide
  参考文献：
  名称：

  [EN] TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES
  [FR] TRIFLUOROMÉTHYLPYRIDINE CARBOXAMIDES COMME PESTICIDES

  摘要：

  化合物的结构式 I（I），其中取代基如权利要求1所定义的那样，可用作杀虫剂。

  公开号：

  WO2014023531A1

文献信息

• Trifluoromethylpyri(mi)dine carboxamides
  申请人：Syngenta Crop Protection, Inc.

  公开号：US06566518B1

  公开（公告）日：2003-05-20

  Compounds of formula are described, along with a method of producing pesticidal compositions and the use of these compounds as pesticides.

  描述了具有该化学式的化合物，以及生产杀虫剂组合物的方法和将这些化合物用作杀虫剂的用途。
• TRIFLUOROMETHYLPYRI(MI)DINE CARBOXAMIDES
  申请人：Syngenta Participations AG

  公开号：EP1200413A1

  公开（公告）日：2002-05-02
• METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS
  申请人：Slater Russell

  公开号：US20130231334A1

  公开（公告）日：2013-09-05

  The invention relates to a method of controlling aphids that are resistant to neonicotinoid insecticides, using a trifluoromethylpyri(mi)dine derivative in free form or in agrochemically acceptable salt form as well as the use of compositions comprising said compound to control neonicontinoid resistant insects. In particular the methods relate to controlling neonicotinoid resistant insects in the Aphididae family, that are resistant to one or more neonicotinoid insecticides. Methods of the invention find particular use in controlling neonicotinoid resistant insects in crops of useful plants. Furthermore, the invention extends to methods of controlling plant viruses spread by neonicotinoid resistant insects.
• US6566518B1
  申请人：——

  公开号：US6566518B1

  公开（公告）日：2003-05-20
• [EN] TRIFLUOROMETHYLPYRI(MI)DINE CARBOXAMIDES<br/>[FR] TRIFLUOROMETHYLPYRI(MI)DINE CARBOXAMIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2001009104A1

  公开（公告）日：2001-02-08

  Compounds of formula (I) are described, wherein R1 and R2, independently of one another, are hydrogen or optionally substituted C1-C6-alkyl, C3-C8-cycloalkyl, C2-C20-alkenyl, C3-C20-alkinyl; or optionally substituted aryl or heterocyclyl; or-C(=O)-R3; R3 is hydrogen, OH, SH, C1-C6-alkyl, C3-C8-cycloalkyl, C1-C6-alkoxy, C1-C6-alkylthio, C2-C6-alkenyl, C3-C6-alkenyloxy, C3-C6-alkinyl, C3-C6-alkinyloxy, di-(C1-C4-alkyl)amine, aryl, heterocyclyl, aryloxy, benzyloxy or heterocyclyloxy; C1-C6-alkyl, C3-C8-cycloalkyl, C1-C6-alkoxy, C1-C6-alkylthio, C3-C6-alkenyl, C3-C6-alkenyloxy, C3-C6-alkinyl or C3-C6-alkinyloxy, which are substituted by one or more substituents selected from the group comprising halogen, nitro, cyano, -OH, -SH, C3-C8-cycloalkyl, halogen-C3-C8-cycloalkyl and di-(C1-C4-alkyl)amine; or aryl, heterocyclyl, aryloxy, benzyloxy or heterocyclyloxy, which are substituted by one to three substituents selected from the group comprising halogen, nitro, cyano, -OH, -SH, COOH, COH, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkylthio, halogen-C1-C6-alkyl, halogen-C1-C6-alkoxy, halogen-C1-C6-alkylthio, C3-C8-cycloalkyl, halogen-C3-C8-cycloalkyl and di-(C1-C4-alkyl)amine; m is 0 or 1; and X is CH or N; or salt thereof; a method of producing and the use of these compounds, pesticides whose active ingredient is selected from these compounds in free form or in agrochemically employable salt form, a method of producing and the use of these compositions, plant propagating material that has been treated with these compositions and a method of controlling pests.