(2-ethoxy-phenethyl)-methyl-amine | 21629-16-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2-ethoxy-phenethyl)-methyl-amine
• 英文别名: (2-Aethoxy-phenaethyl)-methyl-amin；[2-(2-Ethoxyphenyl)ethyl](methyl)amine；2-(2-ethoxyphenyl)-N-methylethanamine
• CAS: 21629-16-3
• 化学式: C₁₁H₁₇NO
• 分子量: 179.262
• InChiKey: ZMELXQLUNQEFML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  硝基脲 、 (2-ethoxy-phenethyl)-methyl-amine 生成 N-(2-ethoxy-phenethyl)-N-methyl-urea
  参考文献：
  名称：

  Pharmacologically Active Compounds from Alkoxy-β-phenylethylamines

  摘要：

  DOI：

  10.1021/ja01283a038
• 作为产物：
  描述：

  2-乙氧基苯乙胺 、 碘甲烷 在 苯甲醛 作用下， 生成 (2-ethoxy-phenethyl)-methyl-amine
  参考文献：
  名称：

  Pharmacologically Active Compounds from Alkoxy-β-phenylethylamines

  摘要：

  DOI：

  10.1021/ja01283a038

文献信息

• [EN] COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING BACTERIAL INFECTIONS<br/>[FR] COMPOSÉS, COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT, L'AMÉLIORATION OU LA PRÉVENTION DES INFECTIONS BACTÉRIENNES
  申请人：BAYLOR COLLEGE MEDICINE

  公开号：WO2020257734A1

  公开（公告）日：2020-12-24

  The disclosure relates, in certain aspects, to the discovery of compounds that can be used to inhibit β-lactamases, such as but not limited to OXA enzymes, such as but not limited to OXA-48. In certain embodiments, these compounds can be used to inhibit activity of β-lactamases in vitro and in vivo.

  该披露涉及在某些方面发现的化合物，可以用于抑制β-内酰胺酶，例如但不限于OXA酶，例如但不限于OXA-48。在某些实施例中，这些化合物可以用于体外和体内抑制β-内酰胺酶的活性。
• Preventives/remedies for urinary disturbance
  申请人：Ishihara Yuji

  公开号：US20050197362A1

  公开（公告）日：2005-09-08

  Preventives/remedies for voiding disturbance containing a compound having both of an acetylcholinesterase inhibitory action and an α1 antagonistic action which exhibits an excellent effect of improving the urinary function of the bladder (i.e., effects of improving urine flow rate and voiding efficiency) without affecting the urinary pressure or the blood pressure.

  具有乙酰胆碱酯酶抑制作用和α1拮抗作用的化合物的预防/治疗措施，可以显著改善膀胱的尿液功能（即改善尿流率和排尿效率的效果），而不影响尿压或血压。
• PREVENTIVES/REMEDIES FOR URINARY DISTURBANCE
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP1466625A1

  公开（公告）日：2004-10-13

  Preventives/remedies for voiding disturbance containing a compound having both of an acetylcholinesterase inhibitory action and an α1 antagonistic action which exhibits an excellent effect of improving the urinary function of the bladder (i.e., effects of improving urine flow rate and voiding efficiency) without affecting the urinary pressure or the blood pressure.

  预防/治疗排尿障碍的药物，其中含有一种同时具有乙酰胆碱酯酶抑制作用和α1拮抗作用的化合物，该化合物在不影响尿压或血压的情况下，对改善膀胱排尿功能（即改善尿流率和排尿效率）具有极佳的效果。
• Substituted 1,2-ethylenediamines, Methods for Preparing Them and Uses Thereof
  申请人：Eickmeier Christian

  公开号：US20090325940A1

  公开（公告）日：2009-12-31

  The present invention relates to substituted 1,2-ethylenediamines of general formula (I) wherein the groups R 1 to R 15 , A, B, L, i as well as X 1 -X 4 are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.
• METHOD FOR PRODUCING CYCLOPLATINIZED PLATINUM COMPLEXES, PLATINUM COMPLEXES PRODUCED BY SAID METHOD, AND THE USE THEREOF
  申请人：Englert Ullrich

  公开号：US20100267977A1

  公开（公告）日：2010-10-21

  The present invention relates to a process for preparing cycloplatinated platinum(II) complexes, platinum(II) complexes prepared by this process and the use thereof for the treatment of tumor diseases and/or hemo blastoses.