1-decyloxy-2-nitrobenzene | 98311-79-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-decyloxy-2-nitrobenzene
• 英文别名: decyl-(2-nitro-phenyl)-ether；Decyl-(2-nitro-phenyl)-aether；1-decoxy-2-nitrobenzene
• CAS: 98311-79-6
• 化学式: C₁₆H₂₅NO₃
• 分子量: 279.379
• InChiKey: CASBYSXOFBAEDS-UHFFFAOYSA-N

物化性质

• 沸点：
  388.8±15.0 °C(Predicted)
• 密度：
  1.020±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-decyloxy-2-nitrobenzene 在 palladium 10% on activated carbon 、 氢气 作用下， 以 乙醇 、 丙酮 为溶剂， 生成 2-[(2-Decoxyphenyl)carbamoyl]benzoic acid
  参考文献：
  名称：

  Synthesis and biological evaluation of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as PTP1B inhibitors

  摘要：

  Based on the fact that petroselinic acid showed good inhibitory activity (IC50 = 6.99 mu mol/L) against protein tyrosine phophatase 1B(PTP1B) in vitro, a series of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives were designed and synthesized. The results indicated that most of the derivatives showed more potent activities against PTP1B. Especially, compound 13 had obvious activity with an IC50 of 106 nmol/L in vitro. (C) 2010 Song Wu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2010.07.005
• 作为产物：
  描述：

  1-碘癸烷 、 硝苯酚 在 18-冠醚-6 、 potassium carbonate 作用下， 以 乙腈 为溶剂， 以79%的产率得到1-decyloxy-2-nitrobenzene
  参考文献：
  名称：

  通过pH介导的构象转换调节固液界面上的大面积自组装

  摘要：

  动态表面：在亚纳米级观察到了由pH值变化引发的2,6-双（1-芳基-1,2,3-三唑-4-基）吡啶（BTP）衍生物的构象转变固-液界面处的STM分辨率。加入三氟乙酸后，两个不同的BTP分子（各自形成一个高度有序的物理吸附单层）经历了从其“玫瑰红”到“四方”形式的显着构象变化，这反映在大面积超过数百个区域的2D自组装急剧变化纳米（见图）。

  DOI：

  10.1002/chem.200802566

文献信息

• Smectic liquid crystal compounds and liquid crystal compositions
  申请人：HITACHI, LTD.

  公开号：EP0110299A2

  公开（公告）日：1984-06-13

  The present invention is characterized by a smectic liquid crystal compound represented by the following formula: wherein R is selected from alkyl and alkoxy groups; m and n are natural numbers: and R* is an optically active group containing an asymmetric carbon atom, and a liquid crystal composition containing said compound as a component. This compound is excellent in optical stability and high-speed response.

  本发明的特征在于一种由下式表示的胶凝液晶化合物： 其中 R 选自烷基和烷氧基； m 和 n 是自然数： 和 R* 是含有不对称碳原子的光学活性基团，以及含有上述化合物的液晶组合物。这种化合物具有优异的光学稳定性和高速响应性。
• ION-SELECTIVE ELECTRODE AND ELECTROLYTE CONCENTRATION DETERMINATION DEVICE
  申请人：Hitachi High-Tech Corporation

  公开号：EP3954987A1

  公开（公告）日：2022-02-16

  The present invention addresses the problem of improving both ion-selective electrode stability and adhesion between a sensitive film and a casing. This ion-selective electrode is characterized by being provided with: a sensitive membrane containing an ion-selective substance, a substrate, and a plasticizer; and a casing that holds the sensitive membrane, and by the casing material containing a substance having a solubility parameter (SP value) of 19.5 to 21.5.

  本发明要解决的问题是提高离子选择电极的稳定性以及敏感膜与外壳之间的附着力。这种离子选择电极的特点是：具有含有离子选择物质的敏感膜、基板和增塑剂；以及固定敏感膜的外壳，外壳材料含有溶解度参数（SP 值）为 19.5 至 21.5 的物质。
• Nodzu et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1951, vol. 71, p. 713
  作者：Nodzu et al.

  DOI：——

  日期：——
• MAGNESIUM ION SELECTIVE PVC MEMBRANES
  申请人：Radiometer Medical ApS

  公开号：EP3818365A1

  公开（公告）日：2021-05-12
• IMPROVED MAGNESIUM ION SELECTIVE MEMBRANES
  申请人：Siemens Healthcare Diagnostics Inc.

  公开号：US20180024088A1

  公开（公告）日：2018-01-25

  The present invention is directed to membranes, sensors, systems and process for the detection of magnesium ions in protein-containing samples. The novel membranes, sensors, systems, and processes are based upon the discovery that the lipophilcity of the plasticizer (or blend of plasticizers) utilized in the formulation of magnesium ion selective membranes for clinical use is inversely proportional to the sensitivity of the plasticizer(s) and directly proportional to the use life thereof.