2-methyl-6,7-dihydro-1H-cyclopenta[gh]perimidine | 50339-36-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类 - 二氮杂萘
• 英文名称: 2-methyl-6,7-dihydro-1H-cyclopenta[gh]perimidine
• 英文别名: 2-methylaceperimidine；2-methyl-6,7-dihydro-1H-cyclopenta[gh]perimidine；2-Methylaceperimidin；6-methyl-5,7-diazatetracyclo[6.5.2.04,15.011,14]pentadeca-1,3,5,8(15),9,11(14)-hexaene
• CAS: 50339-36-1
• 化学式: C₁₄H₁₂N₂
• 分子量: 208.263
• InChiKey: JLIMFEARAGJTIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-methyl-6,7-dihydro-1H-cyclopenta[gh]perimidine 、 溶剂黄146 、 sodium nitrite 以25%的产率得到
  参考文献：
  名称：

  POZHARSKIJ A. F.; KOROLEVA V. N.; GREKOVA I. F.; KASHPAROV I. S., XIMIYA GETEROTSIKL. SOEDIN. , 1975, HO 4, 557-560

  摘要：

  DOI：
• 作为产物：
  描述：

  硝基乙烷 、 5,6-diaminoacenaphthene 在 polyphosphoric acids 作用下， 反应 3.0h， 以92%的产率得到2-methyl-6,7-dihydro-1H-cyclopenta[gh]perimidine
  参考文献：
  名称：

  Electrophilically activated nitroalkanes in the synthesis of 6,7-dihydro-1H-cyclopenta[g]perimidines

  摘要：

  A highly efficient synthetic route to 6,7-dihydro-1H-cyclopenta[gh]perimidines has been proposed on the basis of a novel reaction of nitroalkanes with 4,5-diaminoacenaphthene in the presence of polyphosphoric acid. The reaction involves phosphorylation of the aci-nitro compound, followed by intramolecular cyclization.

  DOI：

  10.1134/s107042801707020x

文献信息

• Electrophilically activated nitroalkanes in the synthesis of 6,7-dihydro-1H-cyclopenta[g]perimidines
  作者：A. V. Aksenov、N. A. Aksenov、D. S. Ovcharov、S. V. Shcherbakov、A. N. Smirnova、I. V. Aksenova、V. I. Goncharov、M. A. Rubin

  DOI：10.1134/s107042801707020x

  日期：2017.7

  A highly efficient synthetic route to 6,7-dihydro-1H-cyclopenta[gh]perimidines has been proposed on the basis of a novel reaction of nitroalkanes with 4,5-diaminoacenaphthene in the presence of polyphosphoric acid. The reaction involves phosphorylation of the aci-nitro compound, followed by intramolecular cyclization.
• POZHARSKIJ A. F.; KOROLEVA V. N.; GREKOVA I. F.; KASHPAROV I. S., XIMIYA GETEROTSIKL. SOEDIN. <KGSS-AQ>, 1975, HO 4, 557-560
  作者：POZHARSKIJ A. F.、 KOROLEVA V. N.、 GREKOVA I. F.、 KASHPAROV I. S.

  DOI：——

  日期：——