1,5,6-trimethyl-1,2,3,4-tetrahydro-pyridine | 101251-96-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1,5,6-trimethyl-1,2,3,4-tetrahydro-pyridine
• 英文别名: 1,5,6-Trimethyl-1,2,3,4-tetrahydro-pyridin；1,5,6-trimethyl-3,4-dihydro-2H-pyridine
• CAS: 101251-96-1
• 化学式: C₈H₁₅N
• 分子量: 125.214
• InChiKey: NBYIBMAPRBKANF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,5,6-trimethyl-1,2,3,4-tetrahydro-pyridine 在 高氯酸 、 乙醚 、 乙醇 作用下， 生成 1,5,6-trimethyl-2,3,4,5-tetrahydro-pyridinium; perchlorate
  参考文献：
  名称：

  Unsaturated Amines. X. The Mercuric Acetate Route to Substituted Piperidines, Δ²-Tetrahydropyridines and Δ²-Tetrahydroanabasines

  摘要：

  DOI：

  10.1021/ja01576a056
• 作为产物：
  描述：

  1,3-二甲基-2(1h)-吡啶酮 在 乙醚 、 溶剂黄146 、 铂 作用下， 生成 1,5,6-trimethyl-1,2,3,4-tetrahydro-pyridine
  参考文献：
  名称：

  Unsaturated Amines. X. The Mercuric Acetate Route to Substituted Piperidines, Δ²-Tetrahydropyridines and Δ²-Tetrahydroanabasines

  摘要：

  DOI：

  10.1021/ja01576a056

文献信息

• NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES
  申请人：BERTHON-CEDILLE Laurence

  公开号：US20090054643A1

  公开（公告）日：2009-02-26

  The invention relates to a method of preparation of fluoroquinolones of formula (I) from compounds of formula (II): in which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and X are as defined in Claim 1.

  该发明涉及一种从化合物（II）制备化合物（I）的氟喹诺酮的方法：其中R1、R2、R3、R4、R5、R6、R7和X的定义如权利要求1中所述。
• CHROMENE COMPOUND
  申请人：Takahashi Toshiaki

  公开号：US20120145974A1

  公开（公告）日：2012-06-14

  A chromene compound which contains a skeleton represented by the following formula (1) and has high color optical density at the time of exposure, double peak characteristic, little initial coloration, a practical fading speed and durability. (wherein R 1 is an electron donor group having a Hammett constant of less than 0, the ring including X is a hetero ring formed together with the 7-position and 8-position carbon atoms, and X is an oxygen atom, sulfur atom or group represented by ═NR 2 directly bonded to the 7-position carbon atom.)

  一种含有以下式子(1)所代表的骨架的香豆素化合物，在曝光时具有高色彩光密度、双峰特性、少量的初始着色、实用的褪色速度和耐久性。(其中，R1是具有小于0的Hammett常数的电子给体基团，包括X的环是与7位和8位碳原子一起形成的杂环，X是直接与7位碳原子键合的氧原子、硫原子或由═NR2表示的基团。)
• HISTONE DEMETHYLASE INHIBITORS
  申请人：Celgene Quanticel Research, Inc.

  公开号：US20160194323A1

  公开（公告）日：2016-07-07

  The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrido[3,4-d]pyrimidin-4-one derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer, melanoma, and the like.

  本发明涉及治疗癌症和肿瘤疾病的组合物和方法。本文提供了取代的吡啶并[3,4-d]嘧啶-4-酮衍生物化合物及包含该化合物的制药组合物。所述化合物和组合物对组蛋白去甲基化酶的抑制具有用途。此外，所述化合物和组合物对治疗癌症，如前列腺癌，乳腺癌，膀胱癌，肺癌，黑色素瘤等具有用途。
• THERMOPLASTIC RESIN COMPOSITION, THERMOPLASTIC RESIN COMPOSITION PRODUCTION METHOD, CELLULOSE-REINFORCED RESIN MOLDED PRODUCT, AND CELLULOSE-REINFORCED RESIN MOLDED PRODUCT MANUFACTURING METHOD
  申请人：Furukawa Electric Co., Ltd.

  公开号：EP3438186A1

  公开（公告）日：2019-02-06

  A method of producing a thermoplastic resin composition containing a thermoplastic synthetic resin and a cellulose, in which at least one type of the thermoplastic synthetic resin is a resin having a group containing a partial structure of an acid anhydride in the polymer molecule; a molded article of a cellulose-reinforced resin; and a method of producing a molded article of a cellulose-reinforced resin.

  一种生产含有热塑性合成树脂和纤维素的热塑性树脂组合物的方法，其中至少一种热塑性合成树脂是在聚合物分子中含有酸酐部分结构基团的树脂； 纤维素增强树脂的模制品；以及 一种生产纤维素增强树脂模制品的方法。
• Sachs, Chemische Berichte, 1899, vol. 32, p. 62
  作者：Sachs

  DOI：——

  日期：——