3β-acetoxy-11-oxo-23,24-dinor-5β-cholanoic acid-(22)-methyl ester | 115211-30-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3β-acetoxy-11-oxo-23,24-dinor-5β-cholanoic acid-(22)-methyl ester
• 英文别名: 3α-acetoxy-11-oxo-23,24-dinor-5β-cholanoic acid-(22)-methyl ester；3α-Acetoxy-11-oxo-20β_F-methyl-5β-pregnansaeure-(21)-methylester；3α-Acetoxy-11-oxo-23,24-dinor-5β-cholansaeure-(22)-methylester
• CAS: 115211-30-8
• 化学式: C₂₅H₃₈O₅
• 分子量: 418.574
• InChiKey: NEOBNUWJCYAWEV-JUFXXIBHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.57
• 重原子数：
  30.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  69.67
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  3β-acetoxy-11-oxo-23,24-dinor-5β-cholanoic acid-(22)-methyl ester 在 氢氧化钾 、 溶剂黄146 、 铂 作用下， 生成 3α,11α-dihydroxy-23,24-dinor-5β-cholanoic acid-(22)-methyl ester
  参考文献：
  名称：

  Double ileoileal intussusception caused by a giant polypoid mass of heterotopic pancreas in a child

  摘要：

  Heterotopic pancreatic tissue has been found in several abdominal and intrathoracic locations. In the ileum, it is a rare, usually asymptomatic, incidental finding.Conclusion A unique case of a recurrent ileoileal intussusception in an 11-year-old girl is presented caused by a giant polypoid mass composed of ectopic pancreatic tissue that remained undetected during several diagnostic tests during two previous admissions and laparoscopic abdominal exploration.

  DOI：

  10.1007/pl00008355
• 作为产物：
  描述：

  3α,12α-diacetoxy-23,24-dinor-5β-cholan-22-oic acid methyl ester 在 吡啶 、 chromium(VI) oxide 、 盐酸 、 氢氧化钾 、 水 、 sodium acetate 、 溶剂黄146 、 丙酮 、 铂 、 锌 、 苯 作用下， 330.0 ℃ 、1.47 kPa 条件下， 生成 3β-acetoxy-11-oxo-23,24-dinor-5β-cholanoic acid-(22)-methyl ester
  参考文献：
  名称：

  Double ileoileal intussusception caused by a giant polypoid mass of heterotopic pancreas in a child

  摘要：

  Heterotopic pancreatic tissue has been found in several abdominal and intrathoracic locations. In the ileum, it is a rare, usually asymptomatic, incidental finding.Conclusion A unique case of a recurrent ileoileal intussusception in an 11-year-old girl is presented caused by a giant polypoid mass composed of ectopic pancreatic tissue that remained undetected during several diagnostic tests during two previous admissions and laparoscopic abdominal exploration.

  DOI：

  10.1007/pl00008355

文献信息

• Sarett, Journal of Biological Chemistry, 1946, vol. 162, p. 601,6307
  作者：Sarett

  DOI：——

  日期：——