2,5-dichlorobenzene-1,4-dimethanol | 2800-99-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,5-dichlorobenzene-1,4-dimethanol
• 英文别名: 2,5-dichloro-1,4-benzenedimethanol；1,4-Bis-(hydroxymethyl)-2,5-dichlorbenzol；2,5-Dichlor-p-xylen-α,α'-diol；1,4-Bis--2,5-dichlor-benzol；2,5-dichloro-1,4-bis-hydroxymethylbenzene；[2,5-Dichloro-4-(hydroxymethyl)phenyl]methanol
• CAS: 2800-99-9
• 化学式: C₈H₈Cl₂O₂
• 分子量: 207.056
• InChiKey: ZNMPGVOXIIHFAP-UHFFFAOYSA-N

物化性质

• 熔点：
  201 °C(Solv: ethanol (64-17-5); benzene (71-43-2)(5:1))
• 沸点：
  353.0±37.0 °C(Predicted)
• 密度：
  1.468±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,5-dichlorobenzene-1,4-dimethanol 在 盐酸 、 氢氰酸 作用下， 以 二甲基亚砜 为溶剂， 生成 Dimethyl α,α,α',α'-Tetracyano-2,5-dichlor-p-phenylendiacetat
  参考文献：
  名称：

  Synthesis of substituted 7,7,8,8-tetracyanoquinodimethanes

  摘要：

  DOI：

  10.1021/jo00909a019
• 作为产物：
  描述：

  2,5-二氯对苯二甲酸 生成 2,5-dichlorobenzene-1,4-dimethanol
  参考文献：
  名称：

  Synthesis of substituted 7,7,8,8-tetracyanoquinodimethanes

  摘要：

  DOI：

  10.1021/jo00909a019

文献信息

• Convenient Synthesis of Some Functionalized Dewar Benzenes and Effect of Chlorine Substitution on the Rates of Their Aromatization
  作者：Takashi Tsuji、Harumi Watanabe、Jun Tanaka、Mari Inada、Shinya Nishida

  DOI：10.1246/cl.1990.1193

  日期：1990.7

  1,4-Bis(hydroxymethyl) Dewar benzenes were prepared in five steps from dimethyl acetylenedicarboxylate in ca. 10% overall yield and rates of their aromatization were measured: dichloro substitution at both the 2,5- and 2,6-positions led to substantial deceleration of the isomerization.

  以约10%的总收率，从二甲基乙炔二羧酸酯出发，通过五步骤合成了1,4-双（羟甲基）DeWar苯，并测定了其芳构化速率：在2,5-和2,6-位置上同时进行二氯取代，显著减缓了异构化过程。
• Hydroxylamine esters as polymerization initiators
  申请人：——

  公开号：US20030216494A1

  公开（公告）日：2003-11-20

  The invention relates to novel cyclic and open-chain hydroxylamine esters and polymerizable compositions comprising these hydroxylamine esters and an ethylenically unsaturated monomer or oligomer. The invention also relates to use as polymerization initiators and to the use of known hydroxylamine esters selected from the group consisting of HALS compounds and the novel hydroxylamine esters for the controlled degradation of polypropylene and for achieving a controlled increase in the molecular weight of polyethylene.

  该发明涉及新型环状和开链羟胺酯以及包括这些羟胺酯和乙烯基不饱和单体或寡聚物的可聚合组合物。该发明还涉及用作聚合引发剂以及用于控制聚丙烯降解和实现聚乙烯分子量控制增加的已知羟胺酯，所述羟胺酯来自HALS化合物和新颖羟胺酯的组合。
• Process for preparing benzylalcohols
  申请人：Dynamit Nobel AG

  公开号：US04283565A1

  公开（公告）日：1981-08-11

  There is described an essentially two step process for the preparation of benzylalcohols including those benzylalcohols having substituents on the benzyene ring by reaction of a substituted or unsubstituted benzyl halide with a formate typically an alkali or alkaline earth metal formate to form the corresponding substituted or unsubstituted benzyl formate. In the second step of the process the benzyl formate is contacted with an alcohol whereby the same is converted into the desired benzylalcohol. Both steps can be performed employing catalysts. Described in the specification is the realization of the desired product in exceptionally high yields in a short period of time whereby the process is characterized by high space-time yields.

  描述了一种基本上分为两个步骤的过程，用于制备苄醇，包括那些苄醇在苯环上有取代基的情况，通过将取代或未取代的苄卤与一种甲酸酯（通常是碱金属或碱土金属甲酸酯）反应，形成相应的取代或未取代的苄甲酸酯。在该过程的第二步中，苄甲酸酯与醇接触，从而转化为所需的苄醇。这两个步骤都可以使用催化剂进行。在说明书中描述了在短时间内以极高产率实现所需产品的情况，该过程以高空时产率为特征。
• METHOD FOR PRODUCING ALCOHOL COMPOUND
  申请人：Hagiya Koji

  公开号：US20120010417A1

  公开（公告）日：2012-01-12

  A method for producing an alcohol compound, wherein a carboxylic acid ester compound is reduced with hydrogen in the presence of a ruthenium complex which is obtained by reacting an imidazolium salt (A) having at least one optionally substituted amino group with a ruthenium compound (B) in the presence of a base (C).

  一种生产醇类化合物的方法，其中在存在一种铑配合物的情况下，通过将至少具有一个可选择取代氨基团的咪唑盐(A)与一种铑化合物(B)在碱(C)的存在下反应而获得的铑配合物，将羧酸酯化合物与氢气还原。
• METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR
  申请人：Aoyagi Yasutaka

  公开号：US20120029195A1

  公开（公告）日：2012-02-02

  A method for producing an alcohol compound, wherein a carboxylic acid ester compound is reduced with hydrogen in the presence of a ruthenium complex which is obtained by reacting a pyridine compound having at least one optionally substituted amino group with a ruthenium compound.

  一种制备醇化合物的方法，其中在存在一种铑配合物的条件下，将羧酸酯化合物与氢还原，所述铑配合物是通过将至少具有一个可选取代氨基团的吡啶化合物与铑化合物反应而得到的。