3-Pyridinecarbodithioic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-Pyridinecarbodithioic acid
• 英文别名: 3-Pyridinedithioic acid；Dithionicotinic acid；pyridine-3-carbodithioic acid
• 化学式: C₆H₅NS₂
• 分子量: 155.244
• InChiKey: AZASHAHJWGFIIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  46
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-Pyridinecarbodithioic acid 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of N-Functionalized/NH-Multisubstituted Indoles, Thienopyrroles, Pyrroloindoles, and Pyrazolopyrroles via Sequential One-Pot Base-Mediated and Copper-Catalyzed Inter- and Intramolecular Amination of 2-[2-Bromo(het)aryl]-3-(het)aryl-3-(methylthio)acrylonitriles

  摘要：

  A novel, efficient route to substituted 1-N-(het)aryl/NH-2-(het)aryl-3-cyanoindoles and related pyrrolo-fused heterocycles such as thienopyrroles, pyrroloindoles, and pyrazolopyrroles has been reported. The overall protocol involves sequential cycloamination of readily available 2-[2-bromo(het)aryl]-3-(het)aryl-3-(methylthio)acrylonitrile precursors with primary amines or amides via two key C-N bond-forming processes, one base-mediated intermolecular and the other Cu-catalyzed intramolecular arylamination leading to N(1)-C(2) and N(1)-C(7a) bond formation, respectively, in a two-step one-pot procedure.

  DOI：

  10.1021/jo501114a
• 作为产物：
  描述：

  劳森试剂 、 烟酸 在 六甲基磷酰三胺 作用下， 以 环己烷 、 乙酸乙酯 为溶剂， 以1.6 g (35%)的产率得到3-Pyridinecarbodithioic acid
  参考文献：
  名称：

  Substituted 2,6-substituted pyridine compounds

  摘要：

  公式为##STR1##的化合物被披露为除草剂。本文披露了在2-和/或6-位置用氟代甲基取代的吡啶3,5-羧酸的环酰胺。还披露了这些化合物的除草用途和含有它们的组合物。

  公开号：

  US04826532A1

文献信息

• Penta-substituted pyridine compounds, herbicidal compositions and
  申请人：Monsanto Company

  公开号：US04988384A1

  公开（公告）日：1991-01-29

  Disclosed herein are herbicidal pyridine compounds substituted at the 3- and/or 5-position with a carboxylic acid-derived heterocyclic moiety, as well as herbicidal compositions and use of these compounds.

  本文揭示了在3-和/或5-位上取代了羧酸衍生的杂环基团的除草吡啶化合物，以及这些化合物的除草组合物和用途。
• COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE
  申请人：Flagship Pioneering Innovations V, Inc.

  公开号：US20210289794A1

  公开（公告）日：2021-09-23

  The invention comprises methods for decreasing colonization by a bacterium of a gut of a stink bug, the method comprising providing a composition comprising vanillin or an analog thereof; and delivering said composition to an egg from which the stink bug will hatch, whereby colonization by the bacterium within the gut of the stink bug hatched from the egg treated with the composition is decreased relative to a stink bug hatched from an untreated egg. In some embodiments, the decrease in colonization by the bacterium decreases the fitness of the stink bug, e.g., decreases reproductive ability, survival, rate of development, number of eggs, number of hatched eggs, adult emergence rate, body length, body width, body mass, or cuticle thickness. In some embodiments of the methods herein, the bacterial colonization-disrupting agent is an inhibitor of bacterial metabolism. In some embodiments, the bacterial colonization-disrupting agent is a polyhydroxyalkanoate (PHA) synthesis inhibitor.
• US4826532A
  申请人：——

  公开号：US4826532A

  公开（公告）日：1989-05-02
• US4988384A
  申请人：——

  公开号：US4988384A

  公开（公告）日：1991-01-29
• US5100461A
  申请人：——

  公开号：US5100461A

  公开（公告）日：1992-03-31