U1TETA

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: U1TETA
• 英文别名: 1-[2-(2-Aminoethylamino)ethyl]imidazolidin-2-one
• 化学式: C₇H₁₆N₄O
• 分子量: 172.23
• InChiKey: KSWGKCLICMFFFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  70.4
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  U1TETA 在 水 、 sodium hydroxide 作用下， 220.0~250.0 ℃ 、3.0 MPa 条件下， 反应 8.5h， 生成 三乙烯四胺
  参考文献：
  名称：

  [EN] TWO-STEP PROCESS FOR CONVERTING CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES
  [FR] PROCÉDÉ EN DEUX ÉTAPES DE CONVERSION D'ALKYLÈNE-URÉES CYCLIQUES EN LEURS ALKYLÈNE-AMINES CORRESPONDANTES

  摘要：

  本发明涉及一种将环状烷基脲转化为相应的烷基胺的过程，包括以下步骤：第一步，在液相中通过与水反应并去除CO2将环状烷基脲转化为相应的烷基胺，以将进料中的5摩尔％至95摩尔％的烷基脲转化为相应的胺；第二步，加入无机碱并将第一步剩余的环状烷基脲与无机碱反应，部分或完全将其转化为相应的烷基胺。发现本发明的两步法使得仍然可以获得高度转化的环状烷基脲，同时使用的强碱明显较少。本发明的过程还表现出比现有技术更高的胺选择性。

  公开号：

  WO2019030193A1
• 作为产物：
  描述：

  1-(2-氨基乙基)-2-咪唑啉酮 、 1,2-二氯乙烷 在 ammonium hydroxide 作用下， 反应 4.0h， 以10%的产率得到U1TETA
  参考文献：
  名称：

  [EN] PROCESS FOR MANUFACTURING ALKYLENEAMINE COMPOUNDS
  [FR] PROCÉDÉ DE PRODUCTION DE COMPOSÉS D'ALKYLÈNEAMINE

  摘要：

  本发明涉及一种制造烷基亚胺化合物的过程，包括以下步骤：在反应介质中，将至少含有一个一级胺基、至少含有一个环状二级胺基或至少含有一个一级胺基和至少含有一个环状二级胺基的烷基脲化合物，以及至少含有一个式I的环状烷基脲基团，其中A选择自C2至C4烷基单元组，可以选择性地被一个或多个C1至C3烷基取代，与一种烷基卤化物反应，形成至少含有一个式I的环状烷基亚胺氢卤酸盐，所述烷基卤化物选择自具有2-6个卤素原子的卤代烷烃和卤代氨基烷，然后将所述烷基亚胺氢卤酸盐与碱反应，形成至少含有一个式I的环状烷基亚胺化合物。在一种实施方式中，反应在氨和额外的烷基亚胺化合物存在下进行。本发明的过程产生的环状和分支副产品较少，直链高烷基亚胺化合物较多，特别是选择自L-TETA，L-TEPA和L-PEHA的直链乙烯亚胺化合物。

  公开号：

  WO2020161146A1

文献信息

• [EN] PROCESS FOR MANUFACTURING A MIXTURE OF STRAIGHT-CHAIN AND NON-STRAIGHT-CHAIN ETHYLENEAMINES<br/>[FR] PROCÉDÉ DE FABRICATION D'UN MÉLANGE D'ÉTHYLÈNEAMINES À CHAÎNES LINÉAIRES ET À CHAÎNES NON LINÉAIRES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019011709A1

  公开（公告）日：2019-01-17

  The invention pertains to a process for manufacturing a mixture of straight-chain higher ethyleneamines and non-straight-chain higher ethyleneamines selected from branched higher ethyleneamines and cyclic higher ethyleneamines, or the urea derivatives thereof, comprising the step of reacting amine-functional compound with ethanolamine-functional compound in the presence of a carbon oxide delivering agent, wherein a) amine-functional compound comprising a combination of straight-chain amine- functional compound and non-straight-chain amine-functional compound is reacted with straight-chain ethanolamine-functional compound, or b) straight-chain amine-functional compound is reacted with ethanolamine-functional compound comprising a combination of straight-chain ethanolamine-functional compound and non-straight-chain ethanolamine-functional compound, or c) amine-functional compound comprising a combinationof straight-chain amine-functional compound and non-straight-chain amine-functional compound is reacted with ethanolamine-functional compound comprising a combination of straight-chain ethanolamine-functional compound and non-straight-chain ethanolamine-functional compound. It has been found that the process according to the invention makes it possible to prepare tailor-made mixtures of straight-chain and non-straight-chain higher ethyleneamines, or urea derivatives thereof.

  该发明涉及一种用于制造直链高乙烯胺和非直链高乙烯胺的混合物的工艺，所述非直链高乙烯胺选自支链高乙烯胺和环状高乙烯胺，或其尿素衍生物，包括以下步骤：在碳氧化物传递剂的存在下，将胺官能化合物与乙醇胺官能化合物反应，其中a）包括直链胺官能化合物和非直链胺官能化合物的组合的胺官能化合物与直链乙醇胺官能化合物发生反应，或b）直链胺官能化合物与包括直链乙醇胺官能化合物和非直链乙醇胺官能化合物组合的乙醇胺官能化合物发生反应，或c）包括直链胺官能化合物和非直链胺官能化合物组合的胺官能化合物与包括直链乙醇胺官能化合物和非直链乙醇胺官能化合物组合的乙醇胺官能化合物发生反应。据发现，根据本发明的工艺可以制备定制的直链和非直链高乙烯胺的混合物，或其尿素衍生物。
• [EN] PROCESS FOR PREPARING CYCLIC ALKYLENE UREAS<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ALKYLÈNE-URÉES CYCLIQUES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030195A1

  公开（公告）日：2019-02-14

  A process for producing a cyclic alkylene urea product of Formula I: in which a compound of Formula II and/or Formula III is contacted in a reaction zone with a compound of Formula IV and/or Formula V and in the presence of one or more carbonyl delivering compounds; in which; R1 is –[A−X−]qR3; R2 is on each occurrence independently selected from H and C1 to C6 alkyl groups which are optionally substituted by one or two groups selected from −OH and −NH2; R3 is on each occurrence independently selected from H and C1 to C6 alkyl groups which are optionally substituted by one or two groups selected from −OH and −NH2; A is on each occurrence independently selected from C1 to C3 alkylene units, optionally substituted by one or more C1 to C3 alkyl groups; X is on each occurrence independently selected from −O−, −NR2−, groups of Formula VI, and groups of Formula VII and p and q are each independently selected from a whole number in the range of from 0 to 8; wherein the compound of Formula II and/or the compound of Formula III are added to a reaction zone comprising compound of Formula IV and/or compound of Formula (V) continuously or semi-continuously over a period of time, or in two or more batches.

  一种生产公式I的环烷基脲产物的方法：在反应区中，将公式II和/或公式III的化合物与公式IV和/或公式V的化合物接触，并在一个或多个羰基供体化合物的存在下进行反应；其中，R1是- [A-X-] qR3; R2在每次出现时独立地选择H和C1到C6烷基，其可以被一个或两个从-OH和-NH2中选择的基团取代；R3在每次出现时独立地选择H和C1到C6烷基，其可以被一个或两个从-OH和-NH2中选择的基团取代；A在每次出现时独立地选择C1到C3烷基单元，其可以被一个或多个C1到C3烷基取代；X在每次出现时独立地选择-O-，-NR2-，公式VI的基团和公式VII的基团；p和q各自独立地选择从0到8的整数；其中，将公式II和/或公式III的化合物连续或半连续地在一段时间内加入包含公式IV和/或公式V的化合物的反应区中，或者分成两个或多个批次加入。
• [EN] PROCESS FOR MANUFACTURING A CYCLIC UREA ADDUCT OF AN ETHYLENEAMINE COMPOUND<br/>[FR] PROCÉDÉ DE FABRICATION DE PRODUIT D'ADDITION D'URÉE CYCLIQUE D'UN COMPOSÉ ÉTHYLÈNEAMINE
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030191A1

  公开（公告）日：2019-02-14

  The invention pertains to a process for manufacturing a cyclic urea adduct of an ethyleneamine compound, the ethyleneamine compound having a linear -NH-CH2-CH2-NH- group, the process comprising the steps of - in an absorption step contacting a liquid medium comprising an ethyleneamine compound having a linear -NH-CH2-CH2-NH- group with a CO2-containing gas stream at a pressure of 1 -20 bara, resulting in the formation of a liquid medium into which CO2 has been absorbed, - bringing the liquid medium to cyclic urea formation conditions, and in an urea formation step forming cyclic urea adduct of the ethyleneamine compound, urea formation conditions including a temperature of at least 120°C, wherein the total pressure at the end of the urea formation step is at most 20 bara, wherein the temperature in the absorption step is lower than the temperature in the urea formation step. It has been found that the process according to the invention makes it possible to obtain cyclic urea adducts in an efficient manner in the absence of metal-containing catalysts and to perform the process under relatively mild conditions, in particular relatively low pressure. More specifically, by separating the CO2 absorption step from the urea formation step, the CO2 absorption step can be carried out at relatively low temperatures and pressures. And because the CO2 is already present in the system at the beginning of the urea formation step, the pressure in the urea formation step does not need to be high.

  该发明涉及一种制造具有线性-NH-CH2-CH2-NH-基团的乙二胺化合物的环式脲加合物的工艺，该工艺包括以下步骤：-在吸收步骤中，将包含具有线性-NH-CH2-CH2-NH-基团的乙二胺化合物的液体介质与含CO2气流在1-20 bara的压力下接触，导致形成已吸收CO2的液体介质，-将液体介质带到环式脲形成条件，并在脲形成步骤中形成乙二胺化合物的环式脲加合物，脲形成条件包括至少120°C的温度，在脲形成步骤结束时的总压力最多为20 bara，在吸收步骤中的温度低于脲形成步骤中的温度。发现该发明的工艺使得在无金属催化剂的情况下以相对温和的条件，特别是相对低压下有效地获得环式脲加合物成为可能。更具体地，通过将CO2吸收步骤与脲形成步骤分离，CO2吸收步骤可以在相对低温和压力下进行。由于在脲形成步骤开始时系统中已经存在CO2，因此脲形成步骤中的压力不需要很高。
• [EN] PROCESS FOR MAKING HIGHER ETHYLENE AMINES<br/>[FR] PROCÉDÉ DE FABRICATION D'ÉTHYLÈNEAMINES SUPÉRIEURES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019011708A1

  公开（公告）日：2019-01-17

  The invention pertains to a process to prepare ethylene amines with n ethyleneunits and n+1 amine groups wherein n is at least 4, or urea derivatives of said ethylene amines, by reacting an ethanolamine-functional compound, an amine-functional compound, and a carbon oxide delivering agent, wherein the ethanolamine-functional compound is of the formula HO-(C2H4-NH-)qH, q is at least 1, the amine-functional compound is of the formula H2N-(C2H4-NH-)rH, r is at least 1, the sum q+r is at least 4 and wherein optionally one or more of the ethanol-amine functional compound or amine-functional compound are at least partly used as their cyclic carbamate derivative, or linear or cyclic urea derivative. The process provides TEPA and higher ethylene amines in high yield and high selectivity, without having to use expensive or hazardous startingmaterials. Various urea derivatives of TEPA and PEHA are also claimed.

  本发明涉及一种制备具有n个乙烯基单元和n+1个胺基的乙烯胺或其脲衍生物的方法，其中n至少为4，通过反应乙醇胺官能化合物、胺官能化合物和一种提供碳氧化物的试剂，其中乙醇胺官能化合物的化学式为HO-(C2H4-NH-)qH，q至少为1，胺官能化合物的化学式为H2N-(C2H4-NH-)rH，r至少为1，q+r的和至少为4，并且可选地，乙醇胺官能化合物或胺官能化合物中的一个或多个可部分用作它们的环状碳酸酯衍生物、线性或环状脲衍生物。该方法提供了高产率和高选择性的TEPA和更高级的乙烯胺，而无需使用昂贵或危险的起始材料。还声明了各种TEPA和PEHA的脲衍生物。
• [EN] PROCESS TO PREPARE ETHYLENE AMINES AND ETHYLENE AMINE DERIVATIVES<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ÉTHYLÈNEAMINES ET DÉRIVÉS D'ÉTHYLÈNEAMINE
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019011710A1

  公开（公告）日：2019-01-17

  The present invention relates to a process to prepare ethyleneamines of the formula NH2-(C2H4-NH-)PI-I wherein p is at least 3, or derivatives thereof wherein one or more units -NH-C2H4-NH- may be present as a cyclic ethylene urea unit or piperazine unit or between two units -NH-C2H4-NH- a carbonyl moiety is present, by reacting an ethanolamine-functional compound OH-(C2H4-NH-)qH wherein q is at least 2, an amine-functional compound NH2-(C2H4-NH-)rH wherein r is at least 1 in the presence of a carbon oxide delivering agent, wherein the molar ratio of ethanolamine-functional compound to amine-functional compound is between 0.05:1 and 0.7:1 and the molar ratio of carbon oxide delivering agent to amine-functional compound is higher than the molar ratio of ethanolamine-functional compound to amine-functional compound, provided that the process is not the process of reacting 3 moles ethylenediamine (EDA) and 1 mole AEEA (aminoethylethanolamine) in the presence of 1.65 moles of urea at 280 deg C for 2 hours.

  本发明涉及一种制备乙烯胺的方法，其化学式为NH2-(C2H4-NH-)PI-I，其中p至少为3，或其衍生物，其中一个或多个单位-NH-C2H4-NH-可以存在为环状乙烯脲基或哌嗪基，或者在两个单位-NH-C2H4-NH-之间存在一个羰基基团。该方法通过在碳氧化物供体的存在下，反应乙醇胺官能化合物OH-(C2H4-NH-)qH（其中q至少为2）和胺官能化合物NH2-(C2H4-NH-)rH（其中r至少为1），其中乙醇胺官能化合物与胺官能化合物的摩尔比在0.05:1至0.7:1之间，碳氧化物供体与胺官能化合物的摩尔比高于乙醇胺官能化合物与胺官能化合物的摩尔比。但该方法不包括在280摄氏度下，将3摩尔乙二胺（EDA）和1摩尔氨基乙醇胺（AEEA）在1.65摩尔脲的存在下反应2小时的方法。