ethyl 2-methylene-3-t-butylthiopropanoate | 92822-43-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethyl 2-methylene-3-t-butylthiopropanoate
• 英文别名: Ethyl 2-[(tert-butylsulfanyl)methyl]prop-2-enoate；ethyl 2-(tert-butylsulfanylmethyl)prop-2-enoate
• CAS: 92822-43-0
• 化学式: C₁₀H₁₈O₂S
• 分子量: 202.318
• InChiKey: PPODVRCBFOIRNZ-UHFFFAOYSA-N

物化性质

• 沸点：
  54 °C(Press: 0.3 Torr)
• 密度：
  0.982±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  ethyl 2-methylene-3-t-butylthiopropanoate 、 Te-(4-methoxyphenyl) benzenecarbotelluroate 反应 26.0h， 以52%的产率得到ethyl 2-methylene-4-oxo-4-phenylbutanoate
  参考文献：
  名称：

  The chemistry of acyl tellurides: generation and trapping of acyl radicals, including aryltellurium group transfer

  摘要：

  DOI：

  10.1021/ja00047a066
• 作为产物：
  描述：

  3-溴-2-(溴甲基)丙酸乙酯 、 叔丁基硫醇 生成 ethyl 2-methylene-3-t-butylthiopropanoate
  参考文献：
  名称：

  BARTON, D. H. R.;CRICH, D., TETRAHEDRON LETT., 1984, 25, N 26, 2787-2790

  摘要：

  DOI：

文献信息

• Synthesis of novel α-amino-acids and derivatives using radical chemistry: synthesis of - and -α-amino-adipic acids, -α
  作者：Derek H.R. Barton、Yolande Hervé、Pierre Potier、Josiane Thierry

  DOI：10.1016/s0040-4020(01)90305-9

  日期：1987.1

  Radicals generated by photolysis (W light) of suitably protected amino-acid derivatives of -hydroxy-2-thiopyridone add efficiently to activated olefins to afford satisfactory yields of adducts. Oxidation of the thiopyridyl residue to sulphoxide and thermal elimination afford excellent yields of the corresponding α, β-unsaturated derivatives. Lateral chain decarboxylation of suitably protected aspartic

  由适当保护的-羟基-2-硫代吡啶酮的氨基酸衍生物经光解（W光）产生的自由基可有效地添加到活化的烯烃中，以提供令人满意的加合物收率。硫代吡啶基残基被氧化成亚砜并进行热消除，可获得极好的产率的相应的α，β-不饱和衍生物。适当保护的天冬氨酸和谷氨酸的侧链脱羧提供了L-α-和D-α-氨基己二酸，-α-氨基庚二酸和-α-氨基-δ-脱氢庚二酸的方便的合成。
• Radical borylation of vinyl azides with NHC-boranes: divergent synthesis of α-boryl ketones and borylated triazoles
  作者：Yifei Zhang、Yangzhen Liao、Peijun Liu、Yu Ran、Xiaozu Liu

  DOI：10.1039/d2ob00076h

  日期：——

  A divergent radical borylation of vinyl azides with N-heterocyclic carbene (NHC) boranes in the presence of tBuSH is described. The protocol enables the divergent synthesis of α-boryl ketones and borylated triazoles with excellent functional group tolerance and a broad substrate scope. Remarkably, this work shows that vinyl azides can serve as unprecedented five-atom synthons for the construction of

  描述了在t BuSH存在下，乙烯基叠氮化物与 N-杂环卡宾 (NHC) 硼烷的发散自由基硼化反应。该协议能够实现α-硼基酮和硼化三唑的不同合成，具有优异的官能团耐受性和广泛的底物范围。值得注意的是，这项工作表明乙烯基叠氮化物可以作为前所未有的五原子合成子用于构建 1,2,3-三唑，而无需 N 2挤出。
• COPOLYMER AND USE THEREOF
  申请人：Shimanaka Hiroyuki

  公开号：US20100120974A1

  公开（公告）日：2010-05-13

  This invention relates a copolymer (D) containing (A) methacrylic polymer units each having, at an end thereof, at least one group represented by the below-described formula (1) and (B) units of an aromatic vinyl monomer, wherein a weight ratio (A:B) of the units (A) to the units (B) is A:B=5 to 95:95 to 5; and its use. The present invention can provide inter alia a copolymer useful as a pigment dispersant or the like capable of affording pigment dispersions useful for inkjet inks, colors for color filters, and other applications.

  本发明涉及一种共聚物（D），其包含（A）甲基丙烯酸聚合物单元，每个单元的末端至少具有下述式（1）所表示的一个基团，并且包含（B）芳香族乙烯单体单元，其中单元（A）和单元（B）的重量比（A：B）为5至95：95至5；以及其用途。本发明可以提供一种共聚物，用作颜料分散剂或类似物，能够提供用于喷墨墨水、彩色滤光片颜色和其他应用的颜料分散剂。
• Barton, Derek H. R.; Crich, David, Journal of the Chemical Society. Perkin transactions I, 1986, p. 1613 - 1620
  作者：Barton, Derek H. R.、Crich, David

  DOI：——

  日期：——
• Photoinduced Free Radical Chemistry of the Acyl Tellurides: Generation, Inter- and Intramolecular Trapping, and ESR Spectroscopic Identification of Acyl Radicals
  作者：David Crich、Chen Chen、Jae-Taeg Hwang、Hongwei Yuan、Aristotle Papadatos、Robert I. Walter

  DOI：10.1021/ja00099a011

  日期：1994.10

  Acyl tellurides are prepared in good to excellent yield by the reaction of sodium aryl tellurides with acyl chlorides, or mixed anhydrides, and are found to be moderately air-stable substances. In contrast to previous literature reports, acyl tellurides of aryl and vinyl carboxylic acids are found to be excellent sources of acyl radicals on photolysis with a simple white light source. The acyl radicals so generated may be trapped intermolecularly by dichalcogenides, or by TEMPO in excellent yield. Trapping by N-tert-butyl-alpha-phenyl nitrone produces a stable nitroxide radical which has been characterized by ESR spectroscopy. The very efficient trapping of acyl radicals by acyl tellurides themselves is demonstrated by a crossover experiment. Acyl tellurides are shown to participate in very efficient radical cyclization reactions onto alkenes with the formation of five-, six-, and eight-membered rings. The immediate products of the cyclizations onto alkenes are alpha-[(aryltelluro)methyl] ketones and the chemistry of these relatively unstable species is briefly described. Treatment with hydrogen peroxide affords alpha-methylene ketones in high yield. When elimination of the aryl telluro group is not possible the alpha-[(aryltelluro)methyl] ketones are stable species that may subsequently be employed in further radical chain reactions, for example with tributyltin hydride and methyl acrylate. Cyclization onto alkynes yields alpha-[(aryltelluro)methylene] ketones which are stable species and which take part in substitution reactions with higher order cuprates or with diphenyl diselenide.