isovaleryl-propionyl-amine | 101252-16-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: isovaleryl-propionyl-amine
• 英文别名: 3-methyl-N-propanoylbutanamide
• CAS: 101252-16-8
• 化学式: C₈H₁₅NO₂
• 分子量: 157.213
• InChiKey: WLJRRGYFXNWHSD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  异戊酰胺 、 丙酸酐 生成 isovaleryl-propionyl-amine
  参考文献：
  名称：

  合成一些二酰亚胺。

  摘要：

  DOI：

  10.1002/jps.3030450715

文献信息

• Tarbouriech, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1903, vol. 137, p. 326
  作者：Tarbouriech

  DOI：——

  日期：——
• Process for preparing poly(N-acylamides) and poly(N-acylamides) as obtained
  申请人：RHODIA OPERATIONS

  公开号：US20150087803A1

  公开（公告）日：2015-03-26

  The present invention relates to a process for preparing a poly(N-acylamide) by reaction between: —at least one compound of the following formula (I): X—R 1 —Y (I) and —at least one compound of the following formula (II): X′—R 2 —Y′ (II) in which: —R 1 and R 2 are, independently of one another, chosen from the group consisting of: a linear or branched alkylene group, comprising from 4 to 20 carbon atoms, an arylene group comprising from 5 to 30 carbon atoms, a heteroarylene group comprising from 5 to 30 atoms, a cycloalkylene group comprising from 5 to 30 carbon atoms, an arylalkylene group comprising from 5 to 30 carbon atoms.
• CRBN LIGANDS AND USES THEREOF
  申请人：Kymera Therapeutics, Inc.

  公开号：US20200347045A1

  公开（公告）日：2020-11-05

  The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CRBN, and the treatment of CRBN-mediated disorders.