4-Heptyloxyacetanilide | 55792-60-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Heptyloxyacetanilide
• 英文别名: 4-n-Heptyloxyacetanilid；4-Heptyloxy-acetanilid；Acetamide, N-[4-(heptyloxy)phenyl]-；N-(4-heptoxyphenyl)acetamide
• CAS: 55792-60-4
• 化学式: C₁₅H₂₃NO₂
• 分子量: 249.353
• InChiKey: VAGVVTDVWFJIGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Heptyloxyacetanilide 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 反应 24.0h， 生成 p-庚氧基苯胺
  参考文献：
  名称：

  Mesomorphic phase transition of a cyclotetraphosphazene containing Schiff base moieties: comparison with the corresponding cyclotriphosphazene

  摘要：

  新制备的八{4-[N-(4′-庚氧基苯基)亚氨基甲基]苯氧基}环四磷腈，由环四磷腈环主链和席夫碱侧链基团组成，被发现可生成一种对映性黏土A相；这是介形环四磷腈的首个实例。

  DOI：

  10.1039/b000497i
• 作为产物：
  描述：

  1-溴代庚烷 、 对乙酰氨基酚 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 生成 4-Heptyloxyacetanilide
  参考文献：
  名称：

  末端杂环对同源系列介晶性质的作用*

  摘要：

  以对羟基苯乙酮和含有肉桂酸酯-偶氮甲碱为中心键的烷氧基苯胺衍生的以硫和氧为杂原子的杂环合成了两个新的同源系列化合物。即。4(furalacryloxy) α-methyl benzylidine-4'-alkoxy aniline 和 4(thianylacryloxy) α-methyl benzylidine-4'-alkoxy aniline。这两个系列的化合物均已通过元素分析、FT-IR、1H-NMR和质谱法表征。已经通过光学偏光显微镜和差示扫描量热法 (DSC) 研究研究了它们的液晶特性。所有衍生物本质上都是介晶的，显示出向列相。

  DOI：

  10.1080/15421400903290501

文献信息

• Substituted pyrazoles as p38 kinase inhibitors
  申请人：Naraian S. Ashok

  公开号：US20070078146A1

  公开（公告）日：2007-04-05

  A class of pyrazole derivatives is described for use in treating p38 kinase medicated disorders. Compounds of particular interest are defined by Formula IA wherein R 1 , R 2 , R 3 and R 4 are as described in the specification.

  描述了一类吡唑衍生物，用于治疗p38激酶介导的疾病。特别感兴趣的化合物由公式IA定义，其中R1、R2、R3和R4如规范中所述。
• Azobenzene-decorated cellulose nanocrystals as photo-switchable chiral solutes in nematic liquid crystals
  作者：Barış Sezgin、Torsten Hegmann

  DOI：10.1039/d2tc04444g

  日期：——

  validate that cellulose nanocrystals (CNCs), surface-functionalized with pro-mesogenic azobenzene pendants, can act as photoswitchable chiral solutes in a nematic liquid crystal (N-LC). Upon UV illumination, the helical pitch and thus the helical twisting power (βw) can be altered based on the trans–cis photoisomerization of the azobenzene pendants. This approach shows that CNCs—biorenewable chiral additives

  在这项工作中，我们验证了用前介晶偶氮苯悬垂物表面功能化的纤维素纳米晶体 (CNC) 可以作为向列液晶 (N-LC) 中的光开关手性溶质。在紫外线照射下，螺距和螺旋扭转力 ( βw ) 可以根据偶氮苯悬垂体的反式-顺式光异构化而改变。这种方法表明，CNCs——具有与 N-LC 分子相称的棒状形状的生物可再生手性添加剂——可以像普通小分子有机手性溶质一样在 LC 相中基于简单的表面修饰进行调整。
• Mesogenicity of Organophosphazenes: The Effect of Phosphazene Rings and Side Groups on the Phase Transition
  作者：Keiichi Moriya、Toshihiro Yamane、Toshiya Suzuki、Tsuyoshi Masuda、Hiroshi Mizusaki、Shinichi Yano、Meisetsu Kajiwara

  DOI：10.1080/10426500212223

  日期：2002.6.1

  Cyclotriphosphazene and cyclotetraphosphazene derivatives with mesogenic 4-N-(4-alkoxyphenyl)iminomethyl)phenoxy and 4-(4'-alkoxy) biphenoxy moieties were synthesized. Schiff base moiety has higher mesomorphic stability than that in biphenyl moiety both in cyclotriphosphazene and cyclotetraphosphazene. Cyclotriphosphazenes possess higher thermal stability in the mesomorphic phase than the cyclotetraphosphazenes, suggesting the difference in the molecular structure.
• Studies of Calamitic Liquid Crystalline Compounds Involving Ester-Azo Central Linkages with a Biphenyl Moiety
  作者：B. T. Thaker、Y. T. Dhimmar、B. S. Patel、D. B. Solanki、N. B. Patel、N. J. Chothani、J. B. Kanojiya

  DOI：10.1080/15421406.2011.591677

  日期：2011.10.14

  Two mesogenic homologous series involving ester-azo central linkages with a biphenyl moiety have been synthesized, such as 4 '-[(4-n-alkoxyphenyl)diazenyl]biphenyl-4-ol (series I) and 4 '-[(4-n-alkoxyphenyl) diazenyl]-4-butoxy phenyl biphenyl-4-carboxylate (series II). Azobiphenyl of series I having a free hydroxyl group with strong hydrogen bonding exhibits a high-temperature enantiotropic smectic phase. Whereas in series II, compounds containing C-1-C-8 carbon atoms exhibit only a monotropic smectic phase and compounds with C-10, C-12, C-14, and C-16 atoms show an enantiotropic smectic phase. These compounds were characterized by elemental analysis, FT-IR, H-1-NMR, and mass spectral studies. The phase transition and mesogenicity of these substances were studied by polarizing optical microscopic and differential scanning calorimetric techniques. Their thermal stabilities and other characteristics are discussed.
• Synthesis and mesomorphic properties of 2,4-bis(4′-n-pentyloxybenzoyloxy)- benzylidine-4″- n-alkoxyaniline
  作者：Wali M. Hamad、Hashim J. Azeez、Ammar H. Al-Dujaili

  DOI：10.1080/15421406.2017.1357426

  日期：2017.7.24

  The synthesis andmesomorphic properties of a new series of 2,4-bis(4'-n-pentyloxybenzoyloxy)- benzylidine-4 ''-n-alkoxyaniline (DC5An) are reported. The molecular structure of compounds was confirmed by FTIR, H-1-NMR, C-13-NMR, mass spectroscopy and elemental analysis. The mesomorphic properties were studied by differential scanning calorimetry (DSC) and polarizing optical microscopy (POM) measurements. All compounds of the series exhibit nematic (N) and smectic C (SmC) phases. The first four homologues (DC5A1-DC5A4) display a N mesophase, whereas the highest homologues (DC5A5-DC5A10) exhibit an enantiotropic dimorphism N and SmC phases. The mesomorphic properties of the present series are compared and discussed with other structurally related series.