zinc (II) trichloroacetate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: zinc (II) trichloroacetate
• 英文别名: zinc(II) trichloroacetate；zinc trichloroacetate；zinc di-(trichloroacetate)；zinc;2,2,2-trichloroacetate
• 化学式: 2C₂Cl₃O₂*Zn
• 分子量: 390.15
• InChiKey: HWNPYGGZWKCKBS-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  8.0
• 可旋转键数：
  0.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.13
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  zinc (II) trichloroacetate 以 acetonitrile 为溶剂， 生成 zinc(II) chloride
  参考文献：
  名称：

  Electrocarboxylation of CCI4 in MeCN during electrolysis with the sacrificial Zn anode

  摘要：

  研究了在带有牺牲性锌阳极的不分流电池中，在 Alk4NBr/MeCN 中对 CCl4 进行静电电羰基化的规律性。电解的主要产物是三氯乙酸锌，它是阴极生成的 CCl3- 阴离子与 CO2 反应的结果。阴极钝化防止了三氯乙酸锌的进一步还原。因此，由于三氯乙酸锌与 Zn0 的化学还原作用，而不是阴极还原作用，会形成少量的二氯乙酸锌和一氯乙酸锌。由于 ZnBr2 在 MeCN 中的溶解度较低，当 Zn2+ 离子在阴极表面放电时会形成少量零价锌。在 MeOH 中用 H2SO4 处理 (Cl3CCOO)2Zn 可得到 Cl3CCO2Me，收率为 11%（以 CCl4 为起始物计算）。

  DOI：

  10.1007/s11172-010-0005-7
• 作为产物：
  描述：

  三氯乙酸 在 zinc(II) oxide 作用下， 以 水 为溶剂， 生成 zinc (II) trichloroacetate
  参考文献：
  名称：

  Salts of zinc and aliphatic haloid carboxylic acids for therapy of skin neoplasms and visible mucous coats

  摘要：

  该发明涉及医学，更具体地说是皮肤病学，即锌和脂肪族卤代羧酸的新盐，可用于治疗良性皮肤病变和可见的粘膜。提议以下锌和脂肪族卤代羧酸盐的化学式 其中在化学式中，氟（F）、氯（Cl）、溴（Br）或碘（I）可以是卤素原子。获得的技术结果是创造一种独特的制剂，用于治疗良性皮肤病变和可见的粘膜。该制剂低毒、作用迅速，具有明显的治疗效果和良好的耐受性。在治疗过程中不会引起并发症，并确保愈合时不形成疤痕组织。所创造的制剂允许扩展治疗类似疾病的药物种类。

  公开号：

  EP1746082A1

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ni: Org.Verb.2, 2.3.1.13, page 313 - 315
  作者：

  DOI：——

  日期：——
• Two novel Zn(II) helical chain polymers containing both bridging and terminal carboxylato groups
  作者：Chirantan Roy Choudhury、Amitabha Datta、Volker Gramlich、G.M. Golzar Hossain、K.M. Abdul Malik、Samiran Mitra

  DOI：10.1016/s1387-7003(03)00108-4

  日期：2003.6

  Two novel carboxylato-bridged Zn(II) polymeric complexes [Zn(L)(CCl3COO)](n) and [Zn(L)(CF3COO)](n), where [L = 2-N-(2'-pyridylimine)benzoic acid] have been synthesized and structurally characterized. The structures of the two complexes are similar with the Zn(L)(Cl3CCO2) or Zn(L)(F3CCO2) units being repeated to form infinite helical chains. In each structure, the neighbouring Zn atoms are bridged sequentially by syn-anti carboxylate groups of the Schiff base. (C) 2003 Elsevier. Science B.V. All rights reserved.
• Zavadovskaya, E.N.; Chernenko, G. M.; Beilin, S. I., Doklady Akademii nauk SSSR, 1973, vol. 209, p. 175 - 177
  作者：Zavadovskaya, E.N.、Chernenko, G. M.、Beilin, S. I.、Sharaev, O. K.、Tinyakova, E. I.、Dolgoplosk, B. A.

  DOI：——

  日期：——
• Synthesis, and crystal and molecular structures of the triflato and trifluoroacetato complexes of zinc, Zn(O3SCF3)2(DME)2 and [Zn(O2CCF3)2(DME)]n
  作者：Daniela Belli Dell'Amico、Daniele Boschi、Fausto Calderazzo、Luca Labella、Fabio Marchetti

  DOI：10.1016/s0020-1693(01)00739-3

  日期：2002.3

  Anhydrous Zn(O3SCF3)(2) and Zn(O2CCX3)(2) X = F, Cl, Br were obtained in substantially quantitative yields from ZnO (or ZnEt2 in the case of the bromide derivative) and a mixture of the corresponding acid and anhydride in heptane as medium. The reactions are rapid and moderately exothermic. Recrystallization of the triflate and trifluoroacetate complexes from dimethoxyethane (DME) produced single crystals of Zn(O3SCF3)(2)(DME)(2) (1) and [Zn(O2CCF3)(2)(DME)](n), (2) suitable for X-ray diffraction studies. In both compounds zinc is hexacoordinated with a pseudo-octahedral geometry. Compound 1 is constituted by mononuclear molecules with terminal monodentate O3SCF3, ligands in trans position. A polynuclear chain structure was found for 2 with zinc atoms joined alternatively by triple and single carboxylato bridges, and with bidentate terminal DME. (C) 2002 Elsevier Science B.V. All rights reserved.
• Thermal investigation and stereochemical studies of some cyclic diamine complexes of nickel(II), zinc(II) and cadmium(II) in the solid state. Part V
  作者：Samiran Mitra、Langonjam Kanhai Singh

  DOI：10.1016/0040-6031(91)80288-t

  日期：1991.3

  Nickel(II), zinc(II) and cadmium(II) complexes of piperazine (pipz), and 1,4-diazacycloheptane (dach) with the composition [Ni(pipz)(TCA)2(H2O)2], [M(dach)2(TAC)2] (M = Ni or Cd), [Zn(pipz)2(TCA)2].H2O, [Zn(dach)2(TCA)2].2H2O and [Cd(pipz)2(TCA)2].2H2O (where TCA represents trichloroacetate ion) have been synthesised. Attempts to prepare N-methylpiperazine and N,N'-dimethylpiperazine complexes of all the metal ions failed. Some intermediate complexes were isolated by pyrolysis. Configurational and conformational changes have been studied by elemental analyses, IR spectra, magnetic moment measurements and thermal analyses. All the complexes and the intermediates appear to be octahedral. Activation energies (E(a)*), enthalpy (DELTA-H) and entropy changes (DELTA-S) for the dehydration and decomposition reactions of the complexes have been evaluated. The order of stability of the complexes (with respect to E(a)*) follows the trend pipz > dach. A linear correlation has been found between E(a)* and DELTA-S for the decomposition of the complexes.