2-{[(5-chlorobenzophenon-2-yl)imino]methyl}-phenol | 109881-51-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-{[(5-chlorobenzophenon-2-yl)imino]methyl}-phenol
• 英文别名: 2-salicylaldimino-5-chlorobenzophenone；5-Chloro-2-(2-hydroxybenzylideneamino)benzophenone；[5-chloro-2-[(2-hydroxyphenyl)methylideneamino]phenyl]-phenylmethanone
• CAS: 109881-51-8
• 化学式: C₂₀H₁₄ClNO₂
• mdl: MFCD00029686
• 分子量: 335.79
• InChiKey: OWKKOKBURZUIED-UHFFFAOYSA-N

物化性质

• 沸点：
  566.7±50.0 °C(Predicted)
• 密度：
  1.20±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  三氯化铬 、 2-{[(5-chlorobenzophenon-2-yl)imino]methyl}-phenol 在 NaOH 作用下， 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Khan, I. U.; Srivastava, S. K.; Srivastava, S. C., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1987, vol. 26, # 3, p. 238 - 240

  摘要：

  DOI：
• 作为产物：
  描述：

  邻甲基苄醇 、 2-氨基-5-氯二苯甲酮 反应 0.05h， 以89%的产率得到2-{[(5-chlorobenzophenon-2-yl)imino]methyl}-phenol
  参考文献：
  名称：

  SOLVENT-FREE SYNTHESES OF SALICYLALDIMINES ASSISTED BY MICROWAVE IRRADIATION

  摘要：

  A microwave-assisted condensation of salicylaldehyde and aryl amines without solvent were efficiently performed to form a series of salicylaldimines in high yields, which were confirmed by IR, H-1 NMR, C-13 NMR and elemental analyses. The microwave-assisted condensation provided a convenient environmental-friendship methodology for syntheses of Schiff-base in organic syntheses.

  DOI：

  10.1081/scc-120006012

文献信息

• Singh, M. S.; Tripathi, U. N.; Raju, M. David, Phosphorus, Sulfur and Silicon and the Related Elements, 1997, vol. 130, p. 147 - 154
  作者：Singh, M. S.、Tripathi, U. N.、Raju, M. David

  DOI：——

  日期：——
• SOLVENT-FREE SYNTHESES OF SALICYLALDIMINES ASSISTED BY MICROWAVE IRRADIATION
  作者：Haijian Yang、Wen-Hua Sun、Zilong Li、Leyong Wang

  DOI：10.1081/scc-120006012

  日期：2002.1

  A microwave-assisted condensation of salicylaldehyde and aryl amines without solvent were efficiently performed to form a series of salicylaldimines in high yields, which were confirmed by IR, H-1 NMR, C-13 NMR and elemental analyses. The microwave-assisted condensation provided a convenient environmental-friendship methodology for syntheses of Schiff-base in organic syntheses.
• Khan, I. U.; Srivastava, S. K.; Srivastava, S. C., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1987, vol. 26, # 3, p. 238 - 240
  作者：Khan, I. U.、Srivastava, S. K.、Srivastava, S. C.

  DOI：——

  日期：——