3,5-dimethyl-4-hydroxy-4'-nitrobenzophenone

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,5-dimethyl-4-hydroxy-4'-nitrobenzophenone
• 英文别名: (4-Hydroxy-3,5-dimethylphenyl)(4-nitrophenyl)methanone；(4-hydroxy-3,5-dimethylphenyl)-(4-nitrophenyl)methanone
• 化学式: C₁₅H₁₃NO₄
• 分子量: 271.273
• InChiKey: PRXNFCOJKASGOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  83.1
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3,5-dimethyl-4-hydroxy-4'-nitrobenzophenone 生成 3,5-dimethyl-4-methoxy-4'-nitrobenzophenone
  参考文献：
  名称：

  HINSHAW, JERALD C.;TONER, JOHN L.;REYNOLDS, GEORGE A.

  摘要：

  DOI：
• 作为产物：
  描述：

  4-硝基苯甲酰氯 、 2,6-二甲基苯酚 以33%的产率得到
  参考文献：
  名称：

  HINSHAW, JERALD C.;TONER, JOHN L.;REYNOLDS, GEORGE A.

  摘要：

  DOI：

文献信息

• Phenolic fluorescent labels
  申请人：Eastman Kodak Company

  公开号：US04670572A1

  公开（公告）日：1987-06-02

  There are described stable fluorescent labels comprising a complex of lanthanide metal and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of said lanthanide metal and at least two heteroatom-containing groups which form coordinate complexes with lanthanide metals and a third heteroatom-containing group or heteratom in or appended to the triplet sensitizer. Labeled physiologically active materials useful in specific binding assays such as labeled antigens, heptens, antibodies, hormones and the like comprising the stable fluorescent labels having physiologically active materials adsorbed or bonded thereto are also described.

  描述了稳定的荧光标记，包括镧系金属和螯合剂的复合物，该螯合剂包括一个三重态敏化剂的核，其三重态能量大于所述镧系金属，并且至少有两个含杂原子的基团，其与镧系金属形成配位络合物，并且第三个含杂原子的基团或杂原子附加到三重态敏化剂中或附加到其上。还描述了标记的生理活性材料，如标记的抗原、肝素、抗体、激素等，其中包括吸附或与稳定的荧光标记结合的生理活性材料，用于特定的结合测定。
• Coumarin chelates
  申请人：Eastman Kodak Company

  公开号：US04801722A1

  公开（公告）日：1989-01-31

  There are described stable fluorescent labels comprising a complex of lanthanide metal and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of said lanthanide metal and at least two heteroatom-containing groups which form coordinate complexes with lanthanide metals and a third heteroatom-containing group or heteratom in or appended to the triplet sensitizer. Labeled physiologically active materials useful in specific binding assays such as labeled antigens, heptens, antibodies, hormones and the like comprising the stable fluorescent labels having physiologically active materials adsorbed or bonded thereto are also described.

  本文描述了稳定的荧光标记物，包括一种镧系金属和螯合剂的复合物，该螯合剂包括一个三重态敏化剂的核，其三重态能量大于所述镧系金属，并且至少有两个含杂原子的基团，这些基团与镧系金属形成配位络合物，并且第三个含杂原子的基团或杂原子附加到三重态敏化剂中或附加到其上。本文还描述了标记的生理活性材料，用于特定结合测定，如标记的抗原、肝素、抗体、激素等，其中包括吸附或与其结合的具有生理活性材料的稳定荧光标记物。
• Fluorescent chelates
  申请人：Eastman Kodak Company

  公开号：US04794191A1

  公开（公告）日：1988-12-27

  There are described stable fluorescent labels comprising a complex of lanthanide metal and a chelating agent comprising a nucleus which is a triplet sensitizer having a triple energy greater than that of said lanthanide metal and at least two heteroatom-containing groups which form coordinate complexes with lanthanide metals and a third heteroatom-containing group or heteratom in or appended to the triplet sensitizer. Labeled physiologically active materials useful in specific binding assays such as labeled antigens, heptens, antibodies, hormones and the like comprising the stable fluorescent labels having physiologically active materials adsorbed or bonded thereto are also described.

  本文描述了稳定的荧光标记物，其中包括镧系金属和螯合剂的复合物，该螯合剂包括一个三重能量大于所述镧系金属的三重敏化剂核心和至少两个含杂原子的基团，这些基团与镧系金属形成配合物，并且第三个含杂原子的基团或者杂原子附加在三重敏化剂上。本文还描述了用于特定结合测定的标记生理活性物质，例如标记抗原、肝素、抗体、激素等，这些生理活性物质吸附或与稳定的荧光标记物结合。
• Fluorescent labels for immunoassay
  申请人：Eastman Kodak Company

  公开号：US04637988A1

  公开（公告）日：1987-01-20

  There are described stable fluorescent labels comprising a complex of lanthanide metal and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of said lanthanide metal and at least two heteroatom-containing groups which form coordinate complexes with lanthanide metals and a third heteroatom-containing group or heteratom in or appended to the triplet sensitizer. Labeled physiologically active materials useful in specific binding assays such as labeled antigens, heptens, antibodies, hormones and the like comprising the stable fluorescent labels having physiologically active materials adsorbed or bonded thereto are also described.

  本文描述了一种稳定的荧光标记，其中包括镧系金属和螯合剂的复合物，螯合剂包括一个三重态敏化剂的核心，其三重态能量大于所述镧系金属，并且至少有两个含杂原子的基团与镧系金属形成配位络合物，第三个含杂原子的基团或杂原子附加到三重态敏化剂上。本文还描述了标记的生理活性材料，例如标记的抗原、肝素、抗体、激素等，这些材料包括吸附或结合到稳定荧光标记上的生理活性材料。
• HINSHAW, JERALD C.;TONER, JOHN L.;REYNOLDS, GEORGE A.
  作者：HINSHAW, JERALD C.、TONER, JOHN L.、REYNOLDS, GEORGE A.

  DOI：——

  日期：——