(E)-2-[2-(2,5-dimethylphenoxymethyl)-phenyl]-2-methoxyiminoacetamide | 156489-54-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-2-[2-(2,5-dimethylphenoxymethyl)-phenyl]-2-methoxyiminoacetamide
• 英文别名: (2E)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyiminoacetamide
• CAS: 156489-54-2
• 化学式: C₁₈H₂₀N₂O₃
• 分子量: 312.368
• InChiKey: RAVZLEBNRHEGFV-LVZFUZTISA-N

物化性质

• 沸点：
  473.3±47.0 °C(predicted)
• 密度：
  1.13±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  73.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (E)-2-[2-(2,5-dimethylphenoxymethyl)-phenyl]-2-methoxyiminoacetamide 、 氯甲烷 在 氢氧化钾 作用下， 以 水 、 甲苯 为溶剂， 生成 醚菌胺
  参考文献：
  名称：

  Process for producing (E)-alkoxyimino or hydroxyimino-acetamide

  摘要：

  本发明涉及一种生产(E)-烷氧基亚胺乙酰胺化合物的工艺，该化合物可用作农业杀菌剂，并涉及一种生产(E)-羟基亚胺乙酰胺化合物的工艺，该化合物可用作生产它们的中间体。本发明还涉及一种生产(E)-甲氧基亚胺乙酰胺化合物的工业过程，该化合物可用作农业杀菌剂。这个工艺在成本、安全性等方面具有优势。

  公开号：

  US05442063A1
• 作为产物：
  描述：

  甲苯 、 盐酸 、 2-[2-(2,5-Dimethylphenoxymethyl)phenyl]-2-methoxyiminoacetamide 在 甲苯 、 magnesium sulfate 、 ethyl acetate n-hexane 作用下， 以 水 为溶剂， 反应 2.0h， 以to give (E)-2-[2-(2,5-dimethylphenoxymethyl)phenyl]-2-methoxyiminoacetamide (1.02 g, Yield: 81.6%) as colorless crystals的产率得到(E)-2-[2-(2,5-dimethylphenoxymethyl)-phenyl]-2-methoxyiminoacetamide
  参考文献：
  名称：

  Process for producing (E)-alkoxyimino or hydroxyimino-acetamide

  摘要：

  本发明涉及一种用作农业杀菌剂的(E)-烷氧基亚胺基乙酰胺化合物的生产过程，以及用作生产它们的中间体的(E)-羟基亚胺基乙酰胺化合物的生产过程。本发明还涉及一种用作农业杀菌剂的(E)-甲氧基亚胺基乙酰胺化合物的工业生产过程。该过程在成本、安全等方面具有优势。

  公开号：

  US05442063A1

文献信息

• Salicylic acid derivatives, processes for their preparation, compositions comprising them, their use
  申请人：——

  公开号：US20020032178A1

  公开（公告）日：2002-03-14

  Salicylic acid derivatives of the formula I, 1 where the index and the substituents have the following meanings: X is halogen, NO 2 , cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being possible for the substituents X to be different from each other if n is greater than 1; A is OH, alkoxy, NH 2 , NHCH 3 or N(CH 3 ) 2 ; R 1 is phenyl, naphthyl, cycloalkyl, 5-membered or 6-membered hetaryl or 5-membered or 6-membered heterocyclyl, comprising one to three N atoms and/or one O or S atom or one or two O and/or S atoms, the ring systems being unsubstituted or substituted; R 2 is hydrogen, cyano, alkyl, alkenyl, alkynyl, haloalkyl, alkoxy or alkylthio, processes for the preparation of these compounds, compositions comprising them, and their use for controlling harmful fungi.

  公式I中的水杨酸衍生物，其中指数和取代基具有以下含义：X是卤素，NO2，氰基，烷基或烷氧基；m为0、1、2或3，如果n大于1，则取代基X可以不同；A是OH，烷氧基，NH2，NHCH3或N（CH3）2；R1是苯基，萘基，环烷基，5元或6元杂芳基或5元或6元杂环烷基，包括一个到三个N原子和/或一个O或S原子或一个或两个O和/或S原子，环系统未取代或取代；R2是氢，氰基，烷基，烯基，炔基，卤代烷基，烷氧基或烷基硫代基，制备这些化合物的方法，包含它们的组合物以及它们用于控制有害真菌的用途。
• Process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds
  申请人：Shionogi & Co., Ltd.

  公开号：US05627284A1

  公开（公告）日：1997-05-06

  The present invention relates to a process for producing (E)-alkoxyiminoacetamide compounds useful as agricultural fungicides and a process for producing (E)-hydroxyiminoacetamide compounds useful as intermediates for producing them. The present invention also relates to an industrial process for producing (E)-methoxyiminoacetamide compounds useful as agricultural fungicides. This process is advantageous in terms of the cost, safety and the like.

  本发明涉及一种生产(E)-烷氧基亚胺基乙酰胺化合物的工艺，该化合物可用作农业杀菌剂，以及一种生产(E)-羟基亚胺基乙酰胺化合物的工艺，该化合物可用作生产农业杀菌剂的中间体。本发明还涉及一种工业生产(E)-甲氧基亚胺基乙酰胺化合物的工艺，该工艺在成本、安全等方面具有优越性。
• Salicylohydrazide derivatives, processes and intermediates for their preparation, compositions comprising them, and their use
  申请人：——

  公开号：US20020019374A1

  公开（公告）日：2002-02-14

  Salicylohydrazide derivatives of the formula I 1 in which the index and the substituents have the following meanings: X is halogen, NO 2 , cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being possible for the substituents X to differ from each other if n is greater than 1; R 1 is NO 2 , NH 2 or NH—CO—A; A is hydrogen, alkyl, alkoxy, NH 2 , NHCH 3 or N(CH 3 ) 2 ; R 2 is hydrogen, cyano, alkyl, alkenyl, alkynyl, haloalkyl, alkoxy or alkylthio; it being possible for the hydrocarbon radicals to be unsubstituted or substituted, R 3 is phenyl, naphthyl, cycloalkyl, 5-membered or 6-membered hetaryl or 5-membered or 6-membered heterocyclyl containing one to three N atoms and/or one O or S atom or one or two O and/or S atoms, the ring systems being unsubstituted or substituted; the preparation of these compounds, compositions comprising them, and their use for controlling harmful fungi.

  化合物I1的苯甲酰肼衍生物，其中指数和取代基具有以下含义：X为卤素，NO2，氰基，烷基或烷氧基；m为0，1，2或3，如果n大于1，则取代基X可以不同；R1为NO2，NH2或NH-CO-A；A为氢，烷基，烷氧基，NH2，NHCH3或N(CH3)2；R2为氢，氰基，烷基，烯基，炔基，卤代烷基，烷氧基或烷硫基；碳氢基团可以是未取代或取代的；R3为苯基，萘基，环戊基，含有1至3个N原子和/或1个O或S原子或1或2个O和/或S原子的5元或6元杂环基或5元或6元杂环基，其环系统可以是未取代或取代的；这些化合物的制备，包括它们的组合物，以及它们用于控制有害真菌的用途。
• Phenethylacrylamide, methods for the production thereof and agents containing the same
  申请人：Grammenos Wassilios

  公开号：US20050181948A1

  公开（公告）日：2005-08-18

  The present invention relates to novel phenethylacrylamides of the formula I in which the substituents R 1 , R 2 , R 3 and R 4 have the following meanings: R 1 is hydrogen, halogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 3 -C 8 -cycloalkyl, C 1 -C 4 -haloalkoxy or C 1 -C 4 -haloalkyl; R 2 is hydrogen, halogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 3 -C 10 -cycloalkyl, C 1 -C 4 -haloalkoxy or C 1 -C 4 -haloalkyl; R 3 is C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, propargyl, C 3 -C 4 -alkenyl or a radical of the formula —H 2 C—C≡C—C(R a , R a )—R c , wherein R a , R b independently of one another are hydrogen or methyl and R c is hydrogen or C 1 -C 4 -alkyl; R 4 is methyl or C 1 -haloalkyl; and Het is a 5- or 6-membered heteroaromatic ring, to processes for their preparation, and to the use of phenethylacrylamides of the formula I for controlling phytopathogenic harmful fungi.

  本发明涉及公式I的新型苯乙基丙烯酰胺，其中取代基R1、R2、R3和R4的含义如下：R1为氢、卤素、C1-C4烷基、C1-C4烷氧基、C3-C8环烷基、C1-C4卤代烷氧基或C1-C4卤代烷基；R2为氢、卤素、C1-C4烷基、C1-C4烷氧基、C3-C10环烷基、C1-C4卤代烷氧基或C1-C4卤代烷基；R3为C1-C4烷基、C1-C4卤代烷基、丙炔基、C3-C4烯基或式—H2C—C≡C—C(Ra, Ra)—Rc的基团，其中Ra、Rb各自独立地为氢或甲基，Rc为氢或C1-C4烷基；R4为甲基或C1卤代烷基；Het为5-或6-成员的杂芳环，本发明还涉及制备这些苯乙基丙烯酰胺的过程，以及利用公式I的苯乙基丙烯酰胺控制植物病原真菌的用途。
• 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi
  申请人：Grote Thomas

  公开号：US20070088026A1

  公开（公告）日：2007-04-19

  5-Phenylpyrimidines of the formula I, in which the substituents have the following meanings: R 1 is a five- to ten-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle comprising one to four hetero atoms selected from the group consisting of O, N or S, which heterocycle can be substituted as defined in the description, R 2 is hydrogen, halogen, cyano, alkyl, haloalkyl or alkoxy; R 3 , R 4 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, R 3 and R 4 together with the nitrogen atom to which they are bonded may also form a five- or six-membered ring which can be interrupted by a hetero atom and have attached to it one or more substituents; R 5 , R 6 are hydrogen, halogen, alkyl, haloalkyl or alkoxy; R 7 , R 8 are hydrogen, halogen, alkyl or haloalkyl; R 9 is hydrogen, halogen, alkyl, alkoxy, cycloalkoxy, haloalkoxy or alkoxycarbonyl, Processes and intermediates for the preparation of these compounds, and their use for controlling harmful fungi.

  式I中的5-苯基嘧啶，其中取代基具有以下含义：R1是一个含有1-4个杂原子（选自O、N或S）的五至十元饱和、部分不饱和或芳香单环或双环杂环，该杂环可以被定义描述中所述地取代；R2是氢、卤素、氰基、烷基、卤代烷基或烷氧基；R3、R4是氢、烷基、卤代烷基、环烷基、卤代环烷基、烯基、卤代烯基、环烯基、炔基、卤代炔基或环炔基，R3和R4与它们连接的氮原子一起也可以形成一个由杂原子打断并附有一个或多个取代基的五元或六元环；R5、R6是氢、卤素、烷基、卤代烷基或烷氧基；R7、R8是氢、卤素、烷基或卤代烷基；R9是氢、卤素、烷基、烷氧基、环烷氧基、卤代烷氧基或烷氧羰基。制备这些化合物的方法和中间体，以及它们用于控制有害真菌的用途。