(3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-5-((2-(trimethylsilyl)ethoxy)methyl)-3a,3b,4,5,7,8,9,9a,9b,10,11,11a-dodecahydro-3H-cyclopenta[i]phenanthridin-1-yl trifluoromethanesulfonate 、
二乙基(3-吡啶基)-硼烷 在
bis-triphenylphosphine-palladium(II) chloride sodium carbonate 作用下,
以
四氢呋喃 、
水 为溶剂,
生成 (3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-1-(pyridin-3-yl)-5-((2-(trimethylsilyl)ethoxy)methyl)-3b,4,5,8,9,9a,9b,10,11,11a-decahydro-3H-cyclopenta[i]phenanthridin-7(3aH)-one