颜料蓝60 | 81-77-6

• 物质功能分类: 染料及颜料 - 染料 - 还原染料
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 中文名称: 颜料蓝60
• 中文别名: 阴丹酮；还原蓝RD；6,15-二氢二蒽并哒嗪-5,9,14,18-四酮；颜料蓝GR；还原蓝RS；阴丹士林蓝；蒽醌蓝；还原蓝4；颜料蓝 6；颜料蓝 60；C.I.颜料蓝60；克劳莫夫塔尔蓝A3R；还原蓝 4；颜料蓝 GR；还原蓝RSN；士林蓝RSN；阴丹士林蓝RSN；C.I.还原蓝4；还原蓝4#；还原兰RSN
• 英文名称: 6,15-dihydroanthrazine-5,9,14,18-tetrone
• 英文别名: vat blue 4；Indanthrene；2,17-diazaheptacyclo[16.12.0.03,16.04,13.06,11.019,28.021,26]triaconta-1(18),3(16),4(13),6,8,10,14,19(28),21,23,25,29-dodecaene-5,12,20,27-tetrone
• CAS: 81-77-6
• 化学式: C₂₈H₁₄N₂O₄
• 分子量: 442.43
• InChiKey: UHOKSCJSTAHBSO-UHFFFAOYSA-N

物化性质

• 熔点：
  470-500°C
• 沸点：
  553.06°C (rough estimate)
• 密度：
  1.3228 (rough estimate)
• LogP：
  1.78 at 20℃
• 物理描述：
  Vat blue 4 appears as blue needles with a metallic luster or fine fluffy deep blue powder. (NTP, 1992)
• 颜色/状态：
  BLUE POWDER
• 溶解度：
  less than 1 mg/mL at 70° F (NTP, 1992)
• 稳定性/保质期：
  EXCELLENT DURABILITY & LIGHT-FASTNESS, NOT DECOMPOSED BY HEATING TO 250 °C

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  34
• 可旋转键数：
  0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  92.3
• 氢给体数：
  2
• 氢受体数：
  6

ADMET

毒理性

• 副作用

职业性肝毒素 - 第二性肝毒素：在职业环境中的毒性效应潜力是基于人类摄入或动物实验的中毒案例。

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

安全信息

• 安全说明：
  S22,S36/37/39
• 危险类别码：
  R20/21/22
• 危险品标志：
  Xi
• 危险品运输编号：
  CB8761100
• RTECS号：
  CB8761100
• 海关编码：
  3204170000
• 危险性防范说明：
  P264,P270,P301+P312+P330,P501
• 危险性描述：
  H302
• 储存条件：
  密封于阴凉处保存。

SDS

---

Section I.Chemical Product and Company Identification
Chemical Name Indanthrone
Portland OR
Synonym C.I. Pigment Blue 60, Cl. 69800
Chemical Formula C28H14N2O4
CAS Number 81-77-6

---

Section II. Composition and Information on Ingredients
Chemical Name CAS Number Percent (%) TLV/PEL Toxicology Data
Indanthrone 81-77-6 --------- Not available. Rat LD50 (oral) 2000mg/kg

---

Section III. Hazards Identification
Acute Health Effects No specific information is available in our data base regarding the toxic effects of this material for humans. However,
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling
this compound.
CARCINOGENIC EFFECTS : Not available.
Chronic Health Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
Toxicity to the reproductive system: Not available.
There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is
not known to aggravate existing medical conditions.

---

Section IV. First Aid Measures
Eye Contact Check for and remove any contact lenses. DO NOT use an eye ointment. Flush eyes with running water for a minimum
of 15 minutes, occasionally lifting the upper and lower eyelids. Seek medical attention. Treat symptomatically and
supportively.
Skin Contact
If the chemical gets spilled on a clothed portion of the body, remove the contaminated clothes as quickly as possible,
protecting your own hands and body. Place the victim under a deluge shower. If the chemical touches the victim's
exposed skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive
soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. Seek
medical attention. Treat symptomatically and supportively. Wash any contaminated clothing before reusing.
Inhalation If the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If
breathing is difficult, oxygen can be administered. Seek medical attention. Treat symptomatically and supportively.
Ingestion Remove dentures if any. Have conscious person drink several glasses of water or milk. INDUCE VOMITING by sticking
finger in throat. Lower the head so that the vomit will not reenter the mouth and throat. NEVER give an unconscious
person anything to ingest. Seek medical attention. Treat symptomatically and supportively.

---

Section V. Fire and Explosion Data
Not available.
Flammability Combustible. Auto-Ignition
Flammable Limits
Flash Points Not available.
Not available.
Combustion Products These products are toxic carbon oxides (CO, CO 2), nitrogen oxides (NO, NO2).
Fire Hazards
No specific information is available regarding the flammability of this compound in the presence of various materials.
Explosion Hazards Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
No additional information is available regarding the risks of explosion.
Fire Fighting Media
SMALL FIRE: Use DRY chemicals, CO 2, water spray or foam.
and Instructions LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Continued on Next Page
Indanthrone

---

Section VI. Accidental Release Measures
Spill Cleanup In case of a spill and/or a leak, always shut off any sources of ignition, ventilate the area, and exercise caution. Use a
Instructions shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any
contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on
disposal.
DSD/Pictogra Handling and Storage
Handling and Storage Keep away from heat and sources of ignition. Mechanical exhaust required. When not in use, tightly seal the container
and store in a dry, cool place. Avoid excessive heat and light. DO NOT breathe dust. In case of insufficient ventilation,
Information
wear suitable respiratory equipment. If you feel unwell, seek medical attention and show the label when possible. Treat
symptomatically and supportively. Avoid contact with skin and eyes.
Always store away from incompatible compounds such as oxidizing agents.

---

Section VIII. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling
this product.
Exposure Limits Not available.

---

Section IX. Physical and Chemical Properties
Solubility
Physical state @ 20°C Powder. Insoluble in cold water, hot water,
methanol, diethyl ether, acetone.
Not available.
Specific Gravity
Molecular Weight 442.43 Partition Coefficient Not available.
Boiling Point Not available. Vapor Pressure Not available.
Melting Point Not available. Vapor Density Not available.
Not available. Volatility Not available.
Refractive Index
Critical Temperature Odor Not available.
Not available.
Viscosity Not available. Taste Not available.

---

Section X. Stability and Reactivity Data
Stability

---

This material is stable if stored under proper conditions. (See Section VII for instructions)
Conditions of Instability
Avoid excessive heat and light.
Incompatibilities
Reactive with strong oxidizing agents.

---

Section XI. Toxicological Information
RTECS Number CB8761100
Routes of Exposure Eye contact. Ingestion. Inhalation.
Rat LD50 (oral) 2000mg/kg
Toxicity Data
Chronic Toxic Effects CARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
Toxicity to the reproductive system: Not available.
There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is not
known to aggravate existing medical conditions.
Acute Toxic Effects No specific information is available in our data base regarding the toxic effects of this material for humans. However,
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling
this compound.
Continued on Next Page
Indanthrone

---

Section XII. Ecological Information
Ecotoxicity Not available.
Environmental Fate Not available.

---

Section XIII. Disposal Considerations
Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with
Waste Disposal
a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state, and local regulations when disposing of this substance.

---

Section XIV. Transport Information
DOT Classification Not a DOT controlled material (United States).
PIN Number Not available.
Proper Shipping Name
Not available.
Packing Group (PG) Not available.
DOT Pictograms

---

Section XV. Other Regulatory Information and Pictograms
TSCA Chemical Inventory This product is ON the EPA Toxic substances control act (TSCA) inventory.
(EPA)
WHMIS Classification
Not controlled under WHMIS (Canada).
(Canada)
EINECS Number (EEC) Not available.
EEC Risk Statements Not available.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

化学性质
深蓝色粉末，不溶于水、乙酸、乙醇、吡啶和二甲苯及甲苯，微溶于氯仿（热）、邻氯苯酚以及喹啉。在浓硫酸中呈棕色，在稀释后会产生蓝色沉淀。于保险粉碱性溶液中呈蓝色，并且在酸性液中呈现红光蓝色。

用途
还原蓝 RSN 主要用于棉纤维染色及棉布印花，也适用于维棉、涤棉织物的两浴套染。对黏胶纤维着色较浅，可与还原蓝、棕、橄榄等拼接成多种颜色，如深灰色等。此外，还应用于制造油墨用颜料。

用途
用于棉纤维的染色以及直接印花，还可加工成颜料。

用途
适用于棉织物的染色。

用途
可用于替代酞菁蓝与永固紫RL配制红光蓝色油漆。

生产方法
方法 1：熔融法。以2-氨基蒽醌为原料，经与温合碱碱熔后用保险粉溶液精制得产物；或以2-氨基蒽醌为原料，二甲亚砜为溶剂，与氢氧化钾进行碱熔反应，再经保险粉溶液精制后得产物。

具体步骤如下：

1. 在缩合锅中加入无水混合碱595kg（氢氧化钾占68%），加热至熔融。然后加入乙酸钠131kg、油酸1.5kg，关闭缩合锅，在氮气保护下于185-190℃条件下反应30min内加入263kg 2-氨基蒽醌，保温1h后加入亚硝酸钠25kg，继续搅拌至完成碱熔反应。
2. 在精制锅中放入5000L水通氮气驱除空气后，放置碱熔物料并搅拌2小时。降温至约51℃左右加入保险粉110kg，在45℃时结晶析出，过滤洗涤滤饼。用含液碱、保险粉和温水的溶液进行洗涤，并用温水洗至微蓝色。
3. 在打浆机中加入染料隐色体湿料及适量水打浆后于60℃氧化6小时，再加入扩散剂NNO150kg进行砂磨。喷雾干燥即得成品。

方法 2：溶剂法。
在缩合锅中加入15L二甲亚砜和6.802kg 2-氨基蒽醌，在约1h内升温至132℃使其基本溶解，继续加热至130-150℃维持30min使其完全溶解，然后通入空气降温至128℃。于10分钟内加入4.4L氢氧化钾溶液（39.8%），再通气保温反应4小时后加水过滤、用热水洗涤滤饼抽干。

在精制锅中加入380L水和滤饼，打浆1小时并加入碱27kg（43%氢氧化钠）。升温至56-57℃加入保险粉5.44kg，在保持温度20分钟后降温结晶析出。过滤洗涤滤饼后用特定溶液再洗一次。

在酸化锅中加水100L，将精制滤饼打浆2小时并调体积至200L，加入硫酸调节pH值（约需10kg 12.34%的硫酸）。搅拌20分钟后过滤用水洗涤至中性吹干。进行砂磨即得成品。

反应信息

• 作为反应物：
  描述：

  颜料蓝60 在 硫酸 、 氨 、 硝酸 作用下， 生成 8-amino-6,15-dihydro-dinaphtho[2,3-a;2',3'-h]phenazine-5,9,14,18-tetraone
  参考文献：
  名称：

  Scholl, Chemische Berichte, 1903, vol. 36, p. 3416

  摘要：

  DOI：
• 作为产物：
  描述：

  1'-amino-1,2'-imino-di-anthraquinone 在 氢氧化钾 、 苯酚 作用下， 生成 颜料蓝60
  参考文献：
  名称：

  DE239211

  摘要：

  公开号：

文献信息

• [EN] METALOXYPHTHALOCYANINE COMPOUNDS<br/>[FR] COMPOSES DE METALOXYPHTALOCYANINE
  申请人：AVECIA LTD

  公开号：WO2004020529A1

  公开（公告）日：2004-03-11

  A phthalocyanine compound of Formula (I) wherein M is an oxymetal group, methods and uses involving these compounds.

  一种配方（I）的邻苯二甲酸酞菁化合物，其中M是一个氧化金属基团，涉及这些化合物的方法和用途。
• Cosmetic compositions
  申请人：Symrise AG

  公开号：EP2745878A1

  公开（公告）日：2014-06-25

  Suggested is a cosmetic compositions comprising (a) a crosspolymer obtained from copolymerisation of at least two different polyols and at least one dicarboxylic acid and (b) at least one fragrance.

  建议的是一种化妆品组合物，包括 (a) 由至少两种不同的多元醇和至少一种二羧酸共聚得到的交联聚合物，以及 (b) 至少一种香料。
• [EN] SULFONIUM SULFATES, THEIR PREPARATION AND USE<br/>[FR] SULFATES DE SULFONIUM, LEUR PRÉPARATION ET UTILISATION
  申请人：BASF SE

  公开号：WO2012113829A1

  公开（公告）日：2012-08-30

  The present invention relates to a heat-curable composition comprising (a) at least one compound which is capable of undergoing cationic polymerization; and (b) at least one sulfonium sulfate selected from compounds of the formulae Ia and Ib where Yn- is a monovalent or divalent anion selected from (1) where n, M, R1 to R10 are as defined in claim 1 and in the description. The present invention also relates to novel sulfonium sulfates of the formulae Ia and Ib, to a process for curing cationically polymerizable material and to the cured material obtained by said process.

  本发明涉及一种热固化组合物，包括（a）至少一种能够进行阳离子聚合的化合物；和（b）选择自式Ia和Ib的至少一种砜酸盐，其中Yn-是从（1）中选择的一价或二价阴离子，其中n、M、R1至R10如权利要求1和描述中所定义。本发明还涉及式Ia和Ib的新型砜酸盐，以及用于固化阳离子聚合材料的工艺和通过该工艺获得的固化材料。
• ALPHA-AMINO ACID DERIVATIVES FOR IMPROVING SOLUBILITY
  申请人：Rudolph Thomas

  公开号：US20110039924A1

  公开（公告）日：2011-02-17

  The invention relates to the use of α-amino acid derivatives for improving the solubility of poorly soluble substances in water or aqueous solutions and to mixtures and preferred preparations.

  这项发明涉及使用α-氨基酸衍生物来提高水或水溶液中难溶物质的溶解度，以及混合物和优选制剂。
• USE OF FLAVONOIDS
  申请人：Rudolph Thomas

  公开号：US20090317342A1

  公开（公告）日：2009-12-24

  The present invention relates to the use of at least one flavonoid for odour improvement and/or odour stabilisation, and to corresponding compositions and the preparation thereof.

  本发明涉及至少一种黄酮类化合物用于改善气味和/或稳定气味，以及相应的组合物及其制备方法。