1-(trimethylsilyl)propyl thioacetate | 17053-46-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: 1-(trimethylsilyl)propyl thioacetate
• 英文别名: Trimethyl-<3-acetylmercapto-propyl>-silan；3-(Trimethylsilyl)propyl-thioacetat；S-3-(trimethylsilyl)propyl ethanethioate；thioacetic acid S-(3-trimethylsilanyl-propyl ester)；Thioessigsaeure-S-(3-trimethylsilyl-propylester)；(3-Acetylmercapto-propyl)-trimethyl-silan；S-3-(trimethylsilyl)propyl ethane-thioate；S-(3-trimethylsilylpropyl) ethanethioate
• CAS: 17053-46-2
• 化学式: C₈H₁₈OSSi
• 分子量: 190.382
• InChiKey: QRGRZPIFTHDQSV-UHFFFAOYSA-N

物化性质

• 沸点：
  92 °C(Press: 12 Torr)
• 密度：
  0.9198 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.99
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(trimethylsilyl)propyl thioacetate 以 苯 为溶剂， 生成 三甲基-丙基硅烷
  参考文献：
  名称：

  Effect of a neighboring trimethylsilyl group on the photochemical and mass spectral fragmentation pathways of S-alkyl thioacetates

  摘要：

  DOI：

  10.1021/jo00925a021
• 作为产物：
  描述：

  (3-氯丙基)三甲基硅烷 在 正丁基锂 、 硫脲 作用下， 以 乙醇 为溶剂， 反应 48.0h， 生成 1-(trimethylsilyl)propyl thioacetate
  参考文献：
  名称：

  The chemistry of sulfines. 13. 2-Thiabicyclo[2.2.1]hept-5-ene and its S-oxides and 3-alkyl derivatives: sulfine and sulfene cyclopentadiene Diels-Alder adducts. Conversion of the cyclopentadiene-sulfine adducts into 2-oxa-3-thiabicyclo[3.3.0]oct-7-enes, novel bicyclic sultenes

  摘要：

  DOI：

  10.1021/jo00381a020

文献信息

• Petrow et al., Zhurnal Obshchei Khimii, 1957, vol. 27, p. 1535,1537,1538; engl.Ausg.S.1609,1611,1612
  作者：Petrow et al.

  DOI：——

  日期：——
• Mironov,V.F. et al., Journal of general chemistry of the USSR, 1967, vol. 37, p. 1588 - 1591
  作者：Mironov,V.F. et al.

  DOI：——

  日期：——
• Acyl iodides in organic synthesis. Reaction of acetyl iodide with thiols
  作者：M. G. Voronkov、O. Yu. Grigor’eva、N. N. Vlasova

  DOI：10.1134/s1070428011120013

  日期：2011.12

  The direction of reactions of acetyl iodide with aliphatic, aromatic, and heterocyclic thiols is determined by the thiol acidity and steric factors. Acetyl iodide reacted with aliphatic thiols, including trialkylsilyl-substituted derivatives R(CH2)(n)SH (R = Me, n = 3; R = Me3Si, n = 3; R = Et3Si, n = 2), to give the corresponding ethanethioates R(CH2)(n)SCOMe. Benzenethiol was oxidized with acetyl iodide to diphenyl disulfide. The reaction of acetyl iodide with 2-sulfanylethanol afforded 2-(2-iodoethyldisulfanyl)ethyl acetate as a result of three consecutive-parallel processes: acylation, iodination, and oxidation of the initial compound. 1,3-Benzothiazole-2-thiol reacted with acetyl iodide only at the nitrogen atom to give quaternary salt, whereas the SH group remained intact.
• Mironow; Pogonkina, Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1959, p. 85,88;engl.Ausg.S.76,78
  作者：Mironow、Pogonkina

  DOI：——

  日期：——
• Synthesis and mass spectra of .omega.-(trimethylsilyl)alkyl methyl sulfides and sulfones
  作者：Thomas Isami Ito、William P. Weber

  DOI：10.1021/jo00925a022

  日期：1974.6