n-Butyl 2,4-dinitrophenyl ether | 13417-44-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: n-Butyl 2,4-dinitrophenyl ether
• 英文别名: butyl-(2,4-dinitro-phenyl)-ether；Butyl-(2,4-dinitro-phenyl)-aether；2.4-Dinitro-1-butyloxy-benzol；2,4-Dinitro-phenol-butylether；O-Butyl-2,4-dinitro-phenol；1-Butoxy-2,4-dinitrobenzene
• CAS: 13417-44-2
• 化学式: C₁₀H₁₂N₂O₅
• 分子量: 240.216
• InChiKey: ZNVRUPHZQXEVSJ-UHFFFAOYSA-N

物化性质

• 熔点：
  99-100 °C
• 沸点：
  379.6±22.0 °C(Predicted)
• 密度：
  1.287±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  101
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  n-Butyl 2,4-dinitrophenyl ether 在 氢氧化钾 作用下， 以 水 、 二甲基亚砜 为溶剂， 生成 2,4-二硝基酚
  参考文献：
  名称：

  Hydrolysis of ethers of 2,4-dinitrophenol. No evidence for a single electron transfer mechanism

  摘要：

  The reactions of 3-butenyl 2,4-dinitrophenyl ether (1), allyl 2,4-dinitrophenyl ether (5), and n-butyl 2,4-dinitrophenyl ether (6) with KOH in two DMSO-water mixtures (50% v/v and 70% v/v) were studied. In all cases, no evidence was found for a single electron transfer mechanism; 2,4-dinitrophenol was the only product formed. The reaction follows the classical S(N)Ar mechanism. The order of reactivity is 5 > 1 > 6 in both solvents, although the reactivities differ only by factors of 1.4 and 2 in 50 and 70% DMSO, respectively.

  DOI：

  10.1021/jo00078a012
• 作为产物：
  描述：

  2,4-二硝基苯乙醚 在 氢氧化钾 、 苯 作用下， 生成 n-Butyl 2,4-dinitrophenyl ether
  参考文献：
  名称：

  Gitis et al., Zhurnal Obshchei Khimii, 1958, vol. 28, p. 2262; engl. Ausg. S. 2299

  摘要：

  DOI：

文献信息

• [EN] ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF<br/>[FR] DÉRIVÉS D'ANHYDRIDE ISATOÏQUE ET LEURS APPLICATIONS
  申请人：UNIV NORTH CAROLINA

  公开号：WO2015163952A1

  公开（公告）日：2015-10-29

  Isatoic anhydride derivatives having an N-substituent which includes a quaternary ammonium group are useful for labeling and/or functionalizing a target material and/or for coupling materials together. The isatoic anhydride derivatives of the present disclosure can be advantageously water soluble, easily prepared and purified. Isatoic anhydride derivatives useful in the present disclosure preferably have at least one chemically reactive group or at least one binding group or at least one detectable label. Anthranilate derivatives made from the isatoic anhydrides derivatives or otherwise and kits including the isatoic anhydride derivatives are also disclosed.

  异烟酰亚胺衍生物具有包括季铵基团的N-取代基，可用于标记和/或功能化目标材料和/或将材料耦合在一起。本公开的异烟酰亚胺衍生物可以具有优势的水溶性，易于制备和纯化。本公开中有用的异烟酰亚胺衍生物最好至少具有一个化学反应性基团或至少一个结合基团或至少一个可检测标记。从异烟酰亚胺衍生物制备的邻氨基苯甲酸酯衍生物或其他衍生物以及包括异烟酰亚胺衍生物的试剂盒也被公开。
• Formation of nitrophenyl ethers from polyols and nitroanisoles
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0335274A2

  公开（公告）日：1989-10-04

  Disclosed is a novel process for effecting an ether interchange reaction by heating together in the presence of a basic catalyst, a nitroaromatic ether or thioether and an organic compound containing at least one hydroxyl or mercapto group. The novelty resides particularly in carrying out the interchange in an inert solvent while sparging the heated reactants thereby to remove at least a portion of solvent along with an evolving alcohol or thiol. The process is particularly adapted to the capping of organic polyols with nitroaromatic ether groups. The capped products are useful as inter­mediates for the preparation of high molecular weight polyamines which in turn find utility in various polymer applications.

  本发明公开了一种新工艺，在碱性催化剂存在下，将硝基芳香族醚或硫醚和含有至少一个羟基或巯基的有机化合物一起加热，从而进行醚互换反应。新颖之处尤其在于在惰性溶剂中进行交换反应，同时对加热的反应物进行喷射，以除去至少一部分溶剂和挥发的醇或硫醇。 该工艺特别适用于有机多元醇与硝基芳香族醚基团的封端。封端的产品可用作制备高分子量多胺的中间体，而高分子量多胺又可用于各种聚合物应用。
• Isatoic anhydride derivatives and applications thereof
  申请人：The University of North Carolina at Charlotte

  公开号：US10179175B2

  公开（公告）日：2019-01-15

  Isatoic anhydride derivatives having an N-substituent which includes a quaternary ammonium group are useful for labeling and/or functionalizing a target material and/or for coupling materials together. The isatoic anhydride derivatives of the present disclosure can be advantageously water soluble, easily prepared and purified. Isatoic anhydride derivatives useful in the present disclosure preferably have at least one chemically reactive group or at least one binding group or at least one detectable label. Anthranilate derivatives made from the isatoic anhydrides derivatives or otherwise and kits including the isatoic anhydride derivatives are also disclosed.

  具有包括季铵基团的 N 取代基的异酸酐衍生物可用于标记和/或官能化目标材料和/或将材料耦合在一起。本公开的异酸酐衍生物可溶于水，易于制备和纯化。本公开中有用的异酸酐衍生物最好具有至少一个化学反应基团或至少一个结合基团或至少一个可检测标签。此外，还公开了由异酸酐衍生物或其他衍生物制成的蒽酸衍生物以及包括异酸酐衍生物的试剂盒。
• Synthesis of substituted acetylenes, aryl–alkyl ethers, 2-alkene-4-ynoates and nitriles using heterogeneous mesoporous Pd-MCM-48 as reusable catalyst
  作者：Subhash Banerjee、Hari Khatri、Vagulejan Balasanthiran、Ranjit T. Koodali、Grigoriy Sereda

  DOI：10.1016/j.tet.2011.05.132

  日期：2011.8

  Pd-MCM-48 has been employed as a heterogeneous catalyst for the synthesis of substituted acetylenes via Sonogashira reactions under copper and amine-free reaction conditions. In addition, the catalyst exhibited excellent regioselectivity for primary alcohols towards C-O coupling leading to formation of alkyl aryl ethers in high yields. A green procedure for the stereoselective synthesis of 2-alkene-4-ynoates and nitriles from the reactions of vic-(E)-diiodoalkenes with activated alkenes has also been demonstrated using Pd-MCM-48 catalyst. The catalyst was easily recovered from the reaction mixture by filtration and reused for at least six times with minimal loss of activity. (C) 2011 Elsevier Ltd. All rights reserved.
• Verkade; van Dijk; Meerburg, Recueil des Travaux Chimiques des Pays-Bas, 1946, vol. 65, p. 346,350, 357
  作者：Verkade、van Dijk、Meerburg

  DOI：——

  日期：——